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Dendropanoxide Induces Autophagy through ERK1/2 Activation in MG-63 Human Osteosarcoma Cells and Autophagy Inhibition Enhances Dendropanoxide-Induced Apoptosis 원문보기

PloS one, v.8 no.12, 2013년, pp.e83611 -   

Lee, Ji-Won (College of Natural Resources and Life Science, Dong-A University, Busan, South Korea) ,  Kim, Kyoung-Sook (College of Natural Resources and Life Science, Dong-A University, Busan, South Korea) ,  An, Hyun-Kyu (College of Natural Resources and Life Science, Dong-A University, Busan, South Korea) ,  Kim, Cheorl-Ho (Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Kyunggi-Do, South Korea) ,  Moon, Hyung-In (College of Natural Resources and Life Science, Dong-A University, Busan, South Korea) ,  Lee, Young-Choon (College of Natural Resources and Life Science, Dong-A University, Busan, South Korea)

Abstract AI-Helper 아이콘AI-Helper

Anticancer effects of dendropanoxide (DP) newly isolated from leaves and stem of Dendropanax morbifera Leveille were firstly investigated in this study. DP inhibited cell proliferation and induced apoptosis in dose- and time-dependent manner in MG-63 human osteosarcoma cells, which was dependent on ...

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