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NTIS 바로가기mBio, v.9 no.4, 2018년, pp.e00948-18 -
Hardwick, J. Marie (Department of Molecular Microbiology and Immunology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA)
ABSTRACTThis question of whether fungi undergo apoptosis-like programmed cell death can be separated into two questions. One question is about applying the term "apoptosis" to fungi, and the other is a more challenging question of whether fungi have evolved mechanisms that inflict self-injury. The a...
1. Ameisen JC 2002 On the origin, evolution, and nature of programmed cell death: a timeline of four billion years . Cell Death Differ 9 : 367 – 393 . doi: 10.1038/sj/cdd/4400950 . 11965491
2. Green DR , Fitzgerald P 2016 Just so stories about the evolution of apoptosis . Curr Biol 26 : R620 – R627 . doi: 10.1016/j.cub.2016.05.023 . 27404257
3. Pounds JA , Bustamante MR , Coloma LA , Consuegra JA , Fogden MP , Foster PN , La Marca E , Masters KL , Merino-Viteri A , Puschendorf R , Ron SR , Sánchez-Azofeifa GA , Still CJ , Young BE 2006 Widespread amphibian extinctions from epidemic disease driven by global warming . Nature 439 : 161 – 167 . doi: 10.1038/nature04246 . 16407945
4. Loo JA 2009 Ecological impacts of non-indigenous invasive fungi as forest pathogens . Biol Invasions 11 : 81 – 96 . doi: 10.1007/s10530-008-9321-3 .
5. Boa E 2004 Wild edible fungi, a global overview of their use and importance to people . Non-wood forest products 17. Food and Agriculture Organization of the United Nations , Rome, Italy http://www.fao.org/docrep/007/y5489e/y5489e00.htm#Contents .
6. Heilmann-Clausen J , Barron ES , Boddy L , Dahlberg A , Griffith GW , Nordén J , Ovaskainen O , Perini C , Senn-Irlet B , Halme P 2015 A fungal perspective on conservation biology . Conserv Biol 29 : 61 – 68 . doi: 10.1111/cobi.12388 . 25185751
7. Bagchi R , Gallery RE , Gripenberg S , Gurr SJ , Narayan L , Addis CE , Freckleton RP , Lewis OT 2014 Pathogens and insect herbivores drive rainforest plant diversity and composition . Nature 506 : 85 – 88 . doi: 10.1038/nature12911 . 24463522
8. Clarke PG , Clarke S 1996 Nineteenth century research on naturally occurring cell death and related phenomena . Anat Embryol 193 : 81 – 99 . doi: 10.1007/BF00214700 . 8742050
9. Appelmans F , Wattiaux R , De Duve C 1955 Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver . Biochem J 59 : 438 – 445 . doi: 10.1042/bj0590438 . 14363114
10. Saunders JW Jr. 1966 Death in embryonic systems . Science 154 : 604 – 612 . doi: 10.1126/science.154.3749.604 . 5332319
11. Petersen NH , Olsen OD , Groth-Pedersen L , Ellegaard AM , Bilgin M , Redmer S , Ostenfeld MS , Ulanet D , Dovmark TH , Lønborg A , Vindeløv SD , Hanahan D , Arenz C , Ejsing CS , Kirkegaard T , Rohde M , Nylandsted J , Jäättelä M 2013 Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase . Cancer Cell 24 : 379 – 393 . doi: 10.1016/j.ccr.2013.08.003 . 24029234
12. Kim A , Cunningham KW 2015 A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress . Mol Biol Cell 26 : 4631 – 4645 . doi: 10.1091/mbc.E15-08-0581 . 26510498
13. Lockshin RA , Williams CM 1964 Programmed cell death–II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths . J Insect Physiol 10 : 643 – 649 . doi: 10.1016/0022-1910(64)90034-4 .
14. Lockshin RA , Williams CM 1965 Programmed cell death–I. Cytology of degeneration in the intersegmental muscles of the Pernyi silkmoth . J Insect Physiol 11 : 123 – 133 . doi: 10.1016/0022-1910(65)90099-5 . 14287218
15. Lockshin RA , William CM 1965 Programmed cell death–III. Neural control of the breakdown of the intersegmental muscles of silkmoths . J Insect Physiol 11 : 601 – 610 . doi: 10.1016/0022-1910(65)90142-3 . 14288380
16. Lockshin RA , Williams CM 1965 Programmed cell death–IV. The influence of drugs on the breakdown of the intersegmental muscles of silkmoths . J Insect Physiol 11 : 803 – 809 . doi: 10.1016/0022-1910(65)90159-9 . 5827539
17. Lockshin RA , Williams CM 1965 Programmed cell death–V. Cytolytic enzymes in relation to the breakdown of the intersegmental muscles of silkmoths . J Insect Physiol 11 : 831 – 844 . doi: 10.1016/0022-1910(65)90186-1 . 5828992
18. Lockshin RA 2016 Programmed cell death 50 (and beyond) . Cell Death Differ 23 : 10 – 17 . doi: 10.1038/cdd.2015.126 . 26564398
19. Ellis HM , Horvitz HR 1986 Genetic control of programmed cell death in the nematode C. elegans . Cell 44 : 817 – 829 . doi: 10.1016/0092-8674(86)90004-8 . 3955651
20. Graninger WB , Seto M , Boutain B , Goldman P , Korsmeyer SJ 1987 Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells . J Clin Invest 80 : 1512 – 1515 . doi: 10.1172/JCI113235 . 3500184
21. White E , Grodzicker T , Stillman BW 1984 Mutations in the gene encoding the adenovirus early region 1B 19,000-molecular-weight tumor antigen cause the degradation of chromosomal DNA . J Virol 52 : 410 – 419 . 6492256
22. Clem RJ , Fechheimer M , Miller LK 1991 Prevention of apoptosis by a baculovirus gene during infection of insect cells . Science 254 : 1388 – 1390 . doi: 10.1126/science.1962198 . 1962198
23. Levine B , Huang Q , Isaacs JT , Reed JC , Griffin DE , Hardwick JM 1993 Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene . Nature 361 : 739 – 742 . doi: 10.1038/361739a0 . 8441470
24. Newmeyer DD , Farschon DM , Reed JC 1994 Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria . Cell 79 : 353 – 364 . doi: 10.1016/0092-8674(94)90203-8 . 7954801
25. Lazebnik YA , Kaufmann SH , Desnoyers S , Poirier GG , Earnshaw WC 1994 Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE . Nature 371 : 346 – 347 . doi: 10.1038/371346a0 . 8090205
26. Minn AJ , Vélez P , Schendel SL , Liang H , Muchmore SW , Fesik SW , Fill M , Thompson CB 1997 Bcl-x(L) forms an ion channel in synthetic lipid membranes . Nature 385 : 353 – 357 . doi: 10.1038/385353a0 . 9002522
27. Yuan J , Shaham S , Ledoux S , Ellis HM , Horvitz HR 1993 The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme . Cell 75 : 641 – 652 . doi: 10.1016/0092-8674(93)90485-9 . 8242740
28. Miura M , Zhu H , Rotello R , Hartwieg EA , Yuan J 1993 Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3 . Cell 75 : 653 – 660 . doi: 10.1016/0092-8674(93)90486-A . 8242741
29. Fernandes-Alnemri T , Litwack G , Alnemri ES 1994 CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme . J Biol Chem 269 : 30761 – 30764 . 7983002
30. Hengartner MO , Ellis RE , Horvitz HR 1992 Caenorhabditis elegans gene ced-9 protects cells from programmed cell death . Nature 356 : 494 – 499 . doi: 10.1038/356494a0 . 1560823
31. Tsujimoto Y , Finger LR , Yunis J , Nowell PC , Croce CM 1984 Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation . Science 226 : 1097 – 1099 . doi: 10.1126/science.6093263 . 6093263
32. Tsujimoto Y , Cossman J , Jaffe E , Croce CM 1985 Involvement of the bcl-2 gene in human follicular lymphoma . Science 228 : 1440 – 1443 . doi: 10.1126/science.3874430 . 3874430
33. Cleary ML , Smith SD , Sklar J 1986 Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation . Cell 47 : 19 – 28 . doi: 10.1016/0092-8674(86)90362-4 . 2875799
34. Vaux DL , Cory S , Adams JM 1988 Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells . Nature 335 : 440 – 442 . doi: 10.1038/335440a0 . 3262202
35. Roberts AW , Davids MS , Pagel JM , Kahl BS , Puvvada SD , Gerecitano JF , Kipps TJ , Anderson MA , Brown JR , Gressick L , Wong S , Dunbar M , Zhu M , Desai MB , Cerri E , Heitner Enschede S , Humerickhouse RA , Wierda WG , Seymour JF 2016 Targeting BCL2 with Venetoclax in relapsed chronic lymphocytic leukemia . N Engl J Med 374 : 311 – 322 . doi: 10.1056/NEJMoa1513257 . 26639348
36. Côrte-Real M 2004 The second international meeting on yeast apoptosis (IMYA 2), Smolenice, Slovak Republic, 17–20 September 2003 . FEMS Yeast Res 4 : 887 – 888 . doi: 10.1016/j.femsyr.2004.04.001 . 15457616
37. Giannattasio S , Mazzoni C 2017 12th international meeting on yeast apoptosis (IMYA) https://imya12.azuleon.org/ . Accessed 5 2018 .
38. Lockshin RA , Zakeri Z 2007 Cell death in health and disease . J Cell Mol Med 11 : 1214 – 1224 . doi: 10.1111/j.1582-4934.2007.00150.x . 18031301
39. Galluzzi L , Vitale I , Aaronson SA , Abrams JM , Adam D , Agostinis P , Alnemri ES , Altucci L , Amelio I , Andrews DW , Annicchiarico-Petruzzelli M , Antonov AV , Arama E , Baehrecke EH , Barlev NA , Bazan NG , Bernassola F , Bertrand MJM , Bianchi K , Blagosklonny MV , Blomgren K , Borner C , Boya P , Brenner C , Campanella M , Candi E , Carmona-Gutierrez D , Cecconi F , Chan FK , Chandel NS , Cheng EH , Chipuk JE , Cidlowski JA , Ciechanover A , Cohen GM , Conrad M , Cubillos-Ruiz JR , Czabotar PE , D’Angiolella V , Dawson TM , Dawson VL , De Laurenzi V , De Mar
40. Carmona-Gutierrez D , Bauer MA , Zimmermann A , Aguilera A , Austriaco N , Ayscough K , Balzan R , Bar-Nun S , Barrientos A , Belenky P , Blondel M , Braun RJ , Breitenbach M , Burhans WC , Büttner S , Cavalieri D , Chang M , Cooper KF , Côrte-Real M , Costa V , Cullin C , Dawes I , Dengjel J , Dickman MB , Eisenberg T , Fahrenkrog B , Fasel N , Fröhlich KU , Gargouri A , Giannattasio S , Goffrini P , Gourlay CW , Grant CM , Greenwood MT , Guaragnella N , Heger T , Heinisch J , Herker E , Herrmann JM , Hofer S , Jiménez-Ruiz A , Jungwirth H ,
41. Skulachev VP 1999 Phenoptosis: programmed death of an organism . Biochemistry (Mosc) 64 : 1418 – 1426 . 10648966
42. Sukhanova EI , Rogov AG , Severin FF , Zvyagilskaya RA 2012 Phenoptosis in yeasts . Biochemistry 77 : 761 – 775 . doi: 10.1134/S0006297912070097 . 22817540
43. Voskoboinik I , Whisstock JC , Trapani JA 2015 Perforin and granzymes: function, dysfunction and human pathology . Nat Rev Immunol 15 : 388 – 400 . doi: 10.1038/nri3839 . 25998963
44. Fabrizio P , Battistella L , Vardavas R , Gattazzo C , Liou LL , Diaspro A , Dossen JW , Gralla EB , Longo VD 2004 Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae . J Cell Biol 166 : 1055 – 1067 . doi: 10.1083/jcb.200404002 . 15452146
45. Severin FF , Hyman AA 2002 Pheromone induces programmed cell death in S. cerevisiae . Curr Biol 12 : R233 – R235 . doi: 10.1016/S0960-9822(02)00776-5 . 11937036
46. Váchová L , Palková Z 2005 Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia . J Cell Biol 169 : 711 – 717 . doi: 10.1083/jcb.200410064 . 15939758
47. Ivanovska I , Hardwick JM 2005 Viruses activate a genetically conserved cell death pathway in a unicellular organism . J Cell Biol 170 : 391 – 399 . doi: 10.1083/jcb.200503069 . 16061692
48. Eastwood MD , Cheung SW , Lee KY , Moffat J , Meneghini MD 2012 Developmentally programmed nuclear destruction during yeast gametogenesis . Dev Cell 23 : 35 – 44 . doi: 10.1016/j.devcel.2012.05.005 . 22727375
49. Weinberger M , Mesquita A , Caroll T , Marks L , Yang H , Zhang Z , Ludovico P , Burhans WC 2010 Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence . Aging (Albany, NY) 2 : 709 – 726 . doi: 10.18632/aging.100215 . 21076178
50. Cáp M , Stěpánek L , Harant K , Váchová L , Palková Z 2012 Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism . Mol Cell 46 : 436 – 448 . doi: 10.1016/j.molcel.2012.04.001 . 22560924
51. Sťovíček V , Váchová L , Palková Z 2012 Yeast biofilm colony as an orchestrated multicellular organism . Commun Integr Biol 5 : 203 – 205 . doi: 10.4161/cib.18912 . 22808334
52. Madeo F , Herker E , Maldener C , Wissing S , Lächelt S , Herlan M , Fehr M , Lauber K , Sigrist SJ , Wesselborg S , Fröhlich KU 2002 A caspase-related protease regulates apoptosis in yeast . Mol Cell 9 : 911 – 917 . doi: 10.1016/S1097-2765(02)00501-4 . 11983181
53. Fannjiang Y , Cheng WC , Lee SJ , Qi B , Pevsner J , McCaffery JM , Hill RB , Basañez G , Hardwick JM 2004 Mitochondrial fission proteins regulate programmed cell death in yeast . Genes Dev 18 : 2785 – 2797 . doi: 10.1101/gad.1247904 . 15520274
54. Lee JE , Westrate LM , Wu H , Page C , Voeltz GK 2016 Multiple dynamin family members collaborate to drive mitochondrial division . Nature 540 : 139 – 143 . doi: 10.1038/nature20555 . 27798601
55. Kowaltowski AJ , Fiskum G 2005 Redox mechanisms of cytoprotection by Bcl-2 . Antioxid Redox Signal 7 : 508 – 514 . doi: 10.1089/ars.2005.7.508 . 15706098
56. Teng X , Dayhoff-Brannigan M , Cheng WC , Gilbert CE , Sing CN , Diny NL , Wheelan SJ , Dunham MJ , Boeke JD , Pineda FJ , Hardwick JM 2013 Genome-wide consequences of deleting any single gene . Mol Cell 52 : 485 – 494 . doi: 10.1016/j.molcel.2013.09.026 . 24211263
57. Chen YB , Aon MA , Hsu YT , Soane L , Teng X , McCaffery JM , Cheng WC , Qi B , Li H , Alavian KN , Dayhoff-Brannigan M , Zou S , Pineda FJ , O’Rourke B , Ko YH , Pedersen PL , Kaczmarek LK , Jonas EA , Hardwick JM 2011 Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential . J Cell Biol 195 : 263 – 276 . doi: 10.1083/jcb.201108059 . 21987637
58. Yi CH , Pan H , Seebacher J , Jang IH , Hyberts SG , Heffron GJ , Vander Heiden MG , Yang R , Li F , Locasale JW , Sharfi H , Zhai B , Rodriguez-Mias R , Luithardt H , Cantley LC , Daley GQ , Asara JM , Gygi SP , Wagner G , Liu CF , Yuan J 2011 Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival . Cell 146 : 607 – 620 . doi: 10.1016/j.cell.2011.06.050 . 21854985
59. Ofengeim D , Chen YB , Miyawaki T , Li H , Sacchetti S , Flannery RJ , Alavian KN , Pontarelli F , Roelofs BA , Hickman JA , Hardwick JM , Zukin RS , Jonas EA 2012 N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death . Nat Neurosci 15 : 574 – 580 . doi: 10.1038/nn.3054 . 22366758
60. Lewis J , Oyler GA , Ueno K , Fannjiang YR , Chau BN , Vornov J , Korsmeyer SJ , Zou S , Hardwick JM 1999 Inhibition of virus-induced neuronal apoptosis by Bax . Nat Med 5 : 832 – 835 . doi: 10.1038/10556 . 10395331
61. Fannjiang Y , Kim CH , Huganir RL , Zou S , Lindsten T , Thompson CB , Mito T , Traystman RJ , Larsen T , Griffin DE , Mandir AS , Dawson TM , Dike S , Sappington AL , Kerr DA , Jonas EA , Kaczmarek LK , Hardwick JM 2003 BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development . Dev Cell 4 : 575 – 585 . doi: 10.1016/S1534-5807(03)00091-1 . 12689595
62. Tang HL , Tang HM , Fung MC , Hardwick JM 2015 In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity . Sci Rep 5 : 9015 . doi: 10.1038/srep09015 . 25757939
63. Berman SB , Chen YB , Qi B , McCaffery JM , Rucker EB III , Goebbels S , Nave KA , Arnold BA , Jonas EA , Pineda FJ , Hardwick JM 2009 Bcl-xL increases mitochondrial fission, fusion, and biomass in neurons . J Cell Biol 184 : 707 – 719 . doi: 10.1083/jcb.200809060 . 19255249
64. Podholová K , Plocek V , Rešetárová S , Kučerová H , Hlaváček O , Váchová L , Palková Z 2016 Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies . Oncotarget 7 : 15299 – 15314 . doi: 10.18632/oncotarget.8084 . 26992228
65. Kim H , Kim A , Cunningham KW 2012 Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeast . J Biol Chem 287 : 19029 – 19039 . doi: 10.1074/jbc.M112.363390 . 22511765
66. Váchová L , Palková Z 2007 Caspases in yeast apoptosis-like death: facts and artefacts . FEMS Yeast Res 7 : 12 – 21 . doi: 10.1111/j.1567-1364.2006.00137.x . 17311581
67. Aouacheria A , Rech de Laval V , Combet C , Hardwick JM 2013 Evolution of Bcl-2 homology motifs: homology versus homoplasy . Trends Cell Biol 23 : 103 – 111 . doi: 10.1016/j.tcb.2012.10.010 . 23199982
68. Shlezinger N , Irmer H , Dhingra S , Beattie SR , Cramer RA , Braus GH , Sharon A , Hohl TM 2017 Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death . Science 357 : 1037 – 1041 . doi: 10.1126/science.aan0365 . 28883073
69. Gonçalves AP , Heller J , Daskalov A , Videira A , Glass NL 2017 Regulated forms of cell death in fungi . Front Microbiol 8 : 1837 . doi: 10.3389/fmicb.2017.01837 . 28983298
70. Hill SM , Nyström T 2015 The dual role of a yeast metacaspase: what doesn’t kill you makes you stronger . Bioessays 37 : 525 – 531 . doi: 10.1002/bies.201400208 . 25677381
71. Lee RE , Brunette S , Puente LG , Megeney LA 2010 Metacaspase Yca1 is required for clearance of insoluble protein aggregates . Proc Natl Acad Sci U S A 107 : 13348 – 13353 . doi: 10.1073/pnas.1006610107 . 20624963
72. Minina EA , Coll NS , Tuominen H , Bozhkov PV 2017 Metacaspases versus caspases in development and cell fate regulation . Cell Death Differ 24 : 1314 – 1325 . doi: 10.1038/cdd.2017.18 . 28234356
73. Aouacheria A , Cunningham KW , Hardwick JM , Palková Z , Powers T , Severin FF , Váchová L 2018 Comment on “Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death” . Science 360 : eaar6910 . doi: 10.1126/science.aar6910 . 29930109
74. Poreba M , Groborz K , Navarro M , Snipas SJ , Drag M , Salvesen GS 2018 Caspase selective reagents for diagnosing apoptotic mechanisms . Cell Death Differ doi: 10.1038/s41418-018-0110-y .
75. Kerr JF , Wyllie AH , Currie AR 1972 Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics . Br J Cancer 26 : 239 – 257 . doi: 10.1038/bjc.1972.33 . 4561027
76. 1972 Apoptosis . Lancet 300 : 1011 – 1012 . doi: 10.1016/S0140-6736(72)92414-2 .
77. Enari M , Sakahira H , Yokoyama H , Okawa K , Iwamatsu A , Nagata S 1998 A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD . Nature 391 : 43 – 50 . doi: 10.1038/34112 . 9422506
78. Sahara S , Aoto M , Eguchi Y , Imamoto N , Yoneda Y , Tsujimoto Y 1999 Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation . Nature 401 : 168 – 173 . doi: 10.1038/43678 . 10490026
79. Coleman ML , Sahai EA , Yeo M , Bosch M , Dewar A , Olson MF 2001 Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I . Nat Cell Biol 3 : 339 – 345 . doi: 10.1038/35070009 . 11283606
80. Segawa K , Kurata S , Yanagihashi Y , Brummelkamp TR , Matsuda F , Nagata S 2014 Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure . Science 344 : 1164 – 1168 . doi: 10.1126/science.1252809 . 24904167
81. Shan B , Pan H , Najafov A , Yuan J 2018 Necroptosis in development and diseases . Genes Dev 32 : 327 – 340 . doi: 10.1101/gad.312561.118 . 29593066
82. Daskalov A , Habenstein B , Sabaté R , Berbon M , Martinez D , Chaignepain S , Coulary-Salin B , Hofmann K , Loquet A , Saupe SJ 2016 Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis . Proc Natl Acad Sci U S A 113 : 2720 – 2725 . doi: 10.1073/pnas.1522361113 . 26903619
83. Daskalov A , Heller J , Herzog S , Fleissner A , Glass NL 2017 Molecular mechanisms regulating cell fusion and heterokaryon formation in filamentous fungi . Microbiol Spectr 5 . doi: 10.1128/microbiolspec.FUNK-0015-2016 .
84. Veneault-Fourrey C , Barooah M , Egan M , Wakley G , Talbot NJ 2006 Autophagic fungal cell death is necessary for infection by the rice blast fungus . Science 312 : 580 – 583 . doi: 10.1126/science.1124550 . 16645096
85. Kershaw MJ , Talbot NJ 2009 Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease . Proc Natl Acad Sci U S A 106 : 15967 – 15972 . doi: 10.1073/pnas.0901477106 . 19717456
86. Xu T , Nicolson S , Denton D , Kumar S 2015 Distinct requirements of autophagy-related genes in programmed cell death . Cell Death Differ 22 : 1792 – 1802 . doi: 10.1038/cdd.2015.28 . 25882046
87. Zhang H , Baehrecke EH 2015 Eaten alive: novel insights into autophagy from multicellular model systems . Trends Cell Biol 25 : 376 – 387 . doi: 10.1016/j.tcb.2015.03.001 . 25862458
88. Skouta R , Dixon SJ , Wang J , Dunn DE , Orman M , Shimada K , Rosenberg PA , Lo DC , Weinberg JM , Linkermann A , Stockwell BR 2014 Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models . J Am Chem Soc 136 : 4551 – 4556 . doi: 10.1021/ja411006a . 24592866
89. Clem RJ 2015 Viral IAPs, then and now . Semin Cell Dev Biol 39 : 72 – 79 . doi: 10.1016/j.semcdb.2015.01.011 . 25652775
90. Shlezinger N , Minz A , Gur Y , Hatam I , Dagdas YF , Talbot NJ , Sharon A 2011 Anti-apoptotic machinery protects the necrotrophic fungus Botrytis cinerea from host-induced apoptotic-like cell death during plant infection . PLoS Pathog 7 : e1002185 . doi: 10.1371/journal.ppat.1002185 . 21876671
91. Byers NM , Vandergaast RL , Friesen PD 2016 Baculovirus inhibitor-of-apoptosis op-IAP3 blocks apoptosis by interaction with and stabilization of a host insect cellular IAP . J Virol 90 : 533 – 544 . doi: 10.1128/JVI.02320-15 . 26491164
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