[논문]Impact of left ventricular hypertrophy on long-term clinical outcomes in hypertensive patients who underwent successful percutaneous coronary intervention with drug-eluting stents

Kim, Yong Hoon; Her, Ae-Young; Choi, Byoung Geol; Choi, Se Yeon; Byun, Jae Kyeong; Baek, Man Jong; Ryu, Yang Gi; Park, Yoonjee; Mashaly, Ahmed; Jang, Won Young; Kim, Woohyeun; Choi, Jah Yeon; Park, Eun Jin; Na, Jin Oh; Choi, Cheol Ung; Lim, Hong Euy; Kim, Eung Ju; Park, Chang Gyu; Seo, Hong Seog; Rha, Seung-Woon

doi:10.1097/MD.0000000000012067

Impact of left ventricular hypertrophy on long-term clinical outcomes in hypertensive patients who underwent successful percutaneous coronary intervention with drug-eluting stents 원문보기

Medicine, v.97 no.35, 2018년, pp.e12067 -

Kim, Yong Hoon (Division of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon) , Her, Ae-Young (Division of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon) , Choi, Byoung Geol (Department of Medicine, Korea University Graduate School) , Choi, Se Yeon (Department of Medicine, Korea University Graduate School) , Byun, Jae Kyeong (Department of Medicine, Korea University Graduate School) , Baek, Man Jong (Department of Thoracic and Cardiovascular Surgery) , Ryu, Yang Gi (Department of Thoracic and Cardiovascular Surgery) , Park, Yoonjee (Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.) , Mashaly, Ahmed (Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.) , Jang, Won Young (Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.) , Kim, Woohyeun (Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.) , Choi, Jah Yeon (Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.) , Park, Eun Jin (Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.) , Na, Jin Oh (Cardiovascular Center,) , Choi, Cheol Ung , Lim, Hong Euy , Kim, Eung Ju , Park, Chang Gyu , Seo, Hong Seog , Rha, Seung-Woon

Abstract ▼ AI-Helper

AbstractLeft ventricular hypertrophy (LVH) is associated with increased risk for vascular events and mortality. This study investigated 8-year clinical outcomes of hypertensive patients with LVH who underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DES) compared with hypertensive patients without LVH.A total of 1704 consecutive hypertensive patients who underwent PCI from 2004 to 2014 were enrolled. We classified them into either the LVH group (n = 406) or the control group (without LVH, n = 1298). LVH was defined by LV mass index > 115 g/m2 in men and > 95 g/m2 in women. After propensity score matched (PSM) analysis, 2 PSM groups (366 pairs, n = 732, c-statistic = 0.629) were generated.For up to 8 years, the LVH group showed a higher incidence of cardiac death (4.4% vs 1.2%, log-rank P = .023, hazard ratio: 3.371, 95% confidence interval: 1.109–10.25; P = .032) compared with the control group. However, there were no significant differences between the 2 groups in the incidence of total death, myocardial infarction, revascularization, and major adverse cardiac events up to 8 years.LVH in hypertensive patients who underwent successful PCI with DES was associated with higher incidence of cardiac death up to 8 years of follow-up. More careful managements and clinical follow-up are needed and treatment strategies should specifically focus to target prevention and reversal of LVH in hypertensive patients.

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참고문헌 (25)

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Impact of left ventricular hypertrophy on long-term clinical outcomes in hypertensive patients who underwent successful percutaneous coronary intervention with drug-eluting stents 원문보기

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Impact of left ventricular hypertrophy on long-term clinical outcomes in hypertensive patients who underwent successful percutaneous coronary intervention with drug-eluting stents 원문보기

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