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p62/ SQSTM 1 as an oncotarget mediates cisplatin resistance through activating RIP 1‐ NF ‐κB pathway in human ovarian cancer cells 원문보기

Cancer Science, v.108 no.7, 2017년, pp.1405 - 1413  

Yan, Xiao‐Yu (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Zhang, Yu (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Zhang, Juan‐Juan (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Zhang, Li‐Chao (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Liu, Ya‐Nan (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Wu, Yao (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Xue, Ya‐Nan (Department of Pathophysiology College of Basic Medical Sciences Jilin University Changchun Jilin China) ,  Lu, Sheng‐Yao (Department of Pathophysiology College of Basic Medical Sciences Jilin University Ch) ,  Su, Jing ,  Sun, Lian‐Kun

Abstract AI-Helper 아이콘AI-Helper

Platinum‐based therapeutic strategies have been widely used in ovarian cancer treatment. However, drug resistance has greatly limited therapeutic efficacy. Recently, tolerance to cisplatin has been attributed to other factors unrelated to DNA. p62 (also known as SQSTM1) functions as a multifu...

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