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Scoparone prevents IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through the PI3K/Akt/NF-κB pathway

Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie, v.106, 2018년, pp.1169 - 1174  

Lu, Chao (Department of Joint Surgery, Xi’an Hong Hui Hospital, Xi’an Jiaotong University Health Science Center) ,  Li, Yanqi (Department of Respiratory, Xi’an Children’s Hospital) ,  Hu, Shouye (Department of Joint Surgery, Xi’an Hong Hui Hospital, Xi’an Jiaotong University Health Science Center) ,  Cai, Yuanzhen (Department of Joint Surgery, Xi’an Hong Hui Hospital, Xi’an Jiaotong University Health Science Center) ,  Yang, Zhi (Department of Joint Surgery, Xi’an Hong Hui Hospital, Xi’an Jiaotong University Health Science Center) ,  Peng, Kan (Department of Joint Surgery, Xi’an Hong Hui Hospital, Xi’an Jiaotong University Health Science Center)

Abstract AI-Helper 아이콘AI-Helper

Abstract Osteoarthritis (OA) is a degenerative joint disease that is commonly accompanied by inflammation. Scoparone is a biologically active constituent isolated from Artemisia capillaris and possesses anti-inflammatory activity. However, the effect of scoparone on inflammatory response in OA has ...

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