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Silicon dioxide nanoparticles induce COX-2 expression through activation of STAT3 signaling pathway in HaCaT cells

Toxicology in vitro : an international journal published in association with BIBRA, v.52, 2018년, pp.235 - 242  

Kundu, Juthika (College of Pharmacy, Keimyung University, Daegu 42601, South Korea) ,  Kim, Do-Hee (College of Pharmacy, Seoul National University, Seoul 08826, South Korea) ,  Chae, In Gyeong (College of Pharmacy, Keimyung University, Daegu 42601, South Korea) ,  Lee, Jong Kwon (Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong 28159, South Korea) ,  Lee, Sooyeun (College of Pharmacy, Keimyung University, Daegu 42601, South Korea) ,  Jeong, Chul-Ho (College of Pharmacy, Keimyung University, Daegu 42601, South Korea) ,  Chun, Kyung-Soo (College of Pharmacy, Keimyung University, Daegu 42601, South Korea)

Abstract AI-Helper 아이콘AI-Helper

Silicon dioxide nanoparticles (SiO2-NPs) are widely used in biomedicines and consumer products, such as sunscreens and cosmetics. However, SiO2-NPs can cause adverse effects on human health, depending on the size and concentration of nanoparticles. The present study was aimed at investigating the mo...

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