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Biatractylolide Modulates PI3K-Akt-GSK3 β -Dependent Pathways to Protect against Glutamate-Induced Cell Damage in PC12 and SH-SY5Y Cells 원문보기

Evidence-based Complementary and Alternative Medicine : eCAM, v.2017, 2017년, pp.1291458 -   

Zhu, Li (Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, China) ,  Ning, Ning (The First Affiliated Hospital, Hunan Normal University, 61 West Jiefang Road, Changsha, Hunan 410005, China) ,  Li, Yu (Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, China) ,  Zhang, Qiu-Fang (Department of Pharmacology, Hubei University of Medicine, Shiyan 442000, China) ,  Xie, Yong-Chao (Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, China) ,  Irshad, Maida (Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, China) ,  Feng, Xing (Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, China) ,  Tao, Xiao-Jun (Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, China)

Abstract AI-Helper 아이콘AI-Helper

Biatractylolide, isolated from the ethyl acetate extract of Atractylodes macrocephala, has shown various pharmacological activities such as antitumor and antioxidant activities. In this work, we aim to study the protective effect of biatractylolide on glutamate-induced rat adrenal pheochromocytoma c...

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