참고문헌 (61)

1. Bae H. Kim R. Kim Y. Lee E. Jin Kim H. Pyo Jang Y. . ( 2012 ). Effects of Schisandra chinensis Baillon (Schizandraceae) on lipopolysaccharide induced lung inflammation in mice . J. Ethnopharmacol. 142 , 41 – 47 . 10.1016/j.jep.2012.04.009 22543173 

   상세보기

2. Barr A. N. Fischer J. H. Koller W. C. Spunt A. L. Singhal A. ( 1988 ). Serum haloperidol concentration and choreiform movements in Huntington's disease . Neurology 38 , 84 – 88 . 10.1212/WNL.38.1.84 2962009 

   상세보기

3. Brouillet E. ( 2014 ). The 3-NP Model of Striatal Neurodegeneration . Curr. Protoc. Neurosci. 67, 9 48 41 – 14 . 10.1002/0471142301.ns0948s67 24723322 

   상세보기

4. Chen N. Chiu P. Y. Ko K. M. ( 2008 ). Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats . Biol. Pharm. Bull. 31 , 1387 – 1391 . 10.1248/bpb.31.1387 18591780 

   상세보기

5. Chen P. Pang S. Yang N. Meng H. Liu J. Zhou N. . ( 2013 ). Beneficial effects of schisandrin B on the cardiac function in mice model of myocardial infarction . PLoS ONE 8 : e79418 . 10.1371/journal.pone.0079418 24260217 

   상세보기

6. Choi J. H. Lee M. J. Jang M. Kim E. J. Shim I. Kim H. J. . ( 2015 ). An Oriental Medicine, Hyungbangpaedok-San Attenuates Motor Paralysis in an Experimental Model of Multiple Sclerosis by Regulating the T Cell Response . PLoS ONE 10 : e0138592 . 10.1371/journal.pone.0138592 26444423 

   상세보기

7. Ci X. Ren R. Xu K. Li H. Yu Q. Song Y. . ( 2010 ). Schisantherin A exhibits anti-inflammatory properties by down-regulating NF-κB and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells . Inflammation 33 , 126 – 136 . 10.1007/s10753-009-9166-7 20238486 

   상세보기

8. Copple I. M. ( 2012 ). The Keap1-Nrf2 cell defense pathway–a promising therapeutic target? Adv. Pharmacol . 63 , 43 – 79 . 10.1016/B978-0-12-398339-8.00002-1 22776639 

   

9. Damiano M. Galvan L. Deglon N. Brouillet E. ( 2010 ). Mitochondria in Huntington's disease . Biochim. Biophys. Acta 1802 , 52 – 61 . 10.1016/j.bbadis.2009.07.012 19682570 

   상세보기

10. Dedeoglu A. Ferrante R. J. Andreassen O. A. Dillmann W. H. Beal M. F. ( 2002 ). Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid . Exp. Neurol. 176 , 262 – 265 . 10.1006/exnr.2002.7933 12093104 

    상세보기

11. Ferger A. I. Campanelli L. Reimer V. Muth K. N. Merdian I. Ludolph A. C. . ( 2010 ). Effects of mitochondrial dysfunction on the immunological properties of microglia . J. Neuroinflammation 7 : 45 . 10.1186/1742-2094-7-45 20701773 

    상세보기

12. Fernagut P. O. Diguet E. Stefanova N. Biran M. Wenning G. K. Canioni P. . ( 2002 ). Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation . Neuroscience 114 , 1005 – 1017 . 10.1016/S0306-4522(02)00205-1 12379255 

    상세보기

13. Franklin K. B. J. Paxinos G. ( 2008 ). The Mouse Brain in Stereotaxic Coordinates . San Iego, CA : Elsevier Academic Press . 

14. Fu M. Sun Z. H. Zong M. He X. P. Zuo H. C. Xie Z. P. ( 2008 ). Deoxyschisandrin modulates synchronized Ca 2+ oscillations and spontaneous synaptic transmission of cultured hippocampal neurons . Acta Pharmacol. Sin. 29 , 891 – 898 . 10.1111/j.1745-7254.2008.00821.x 18664321 

    상세보기

15. Giridharan V. V. Thandavarayan R. A. Arumugam S. Mizuno M. Nawa H. Suzuki K. . ( 2015 ). Schisandrin B Ameliorates ICV-infused amyloid beta induced oxidative stress and neuronal dysfunction through inhibiting RAGE/NF-kappaB/MAPK and Up-Regulating HSP/Beclin expression . PLoS ONE 10 : e0142483 . 10.1371/journal.pone.0142483 26556721 

    상세보기

16. Harper S. J. Wilkie N. ( 2003 ). MAPKs: new targets for neurodegeneration . Expert Opin. Ther. Targets 7 , 187 – 200 . 10.1517/14728222.7.2.187 12667097 

    상세보기

17. He J. L. Zhou Z. W. Yin J. J. He C. Q. Zhou S. F. Yu Y. ( 2014 ). Schisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathway . Drug Des. Devel. Ther. 9 , 127 – 146 . 10.2147/DDDT.S68501 25552902 

    상세보기

18. Huang Q. Y. Wei C. Yu L. Coelho J. E. Shen H. Y. Kalda A. ( 2006 ). Adenosine A2A receptors in bone marrow-derived cells but not in forebrain neurons are important contributors to 3-nitropropionic acid-induced striatal damage as revealed by cell-type-selective inactivation . J. Neurosci. 26 , 11371 – 11378 . 10.1523/JNEUROSCI.1907-06.2006 17079665 

    상세보기

19. Huh ( 1613 ). Donguibogam: Naeuiwon. Hanyang : Naeuiwon . 

20. Huntington Study Group ( 2006 ). Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial . Neurology 66 , 366 – 372 . 10.1212/01.wnl.0000198586.85250.13 16476934 

    상세보기

21. Jang M. Cho I. H. ( 2016 ). Sulforaphane Ameliorates 3-Nitropropionic Acid-Induced Striatal Toxicity by Activating the Keap1-Nrf2-ARE Pathway and Inhibiting the MAPKs and NF-kappaB Pathways . Mol. Neurobiol. 53 , 2619 – 2635 . 10.1007/s12035-015-9230-2 26096705 

    상세보기

22. Jang M. Lee M. J. Cho I. H. ( 2014 ). Ethyl pyruvate ameliorates 3-nitropropionic acid-induced striatal toxicity through anti-neuronal cell death and anti-inflammatory mechanisms . Brain Behav. Immun. 38 , 151 – 165 . 10.1016/j.bbi.2014.01.015 24576481 

    상세보기

23. Jang M. Lee M. J. Kim C. S. Cho I. H. ( 2013 ). Korean red ginseng extract attenuates 3-Nitropropionic Acid-Induced Huntington's-Like Symptoms . Evid. Based Complement. Alternat. Med. , 2013 : 237207 . 10.1155/2013/237207 23431333 

    상세보기

24. Jiang E. P. Wang S. Q. Wang Z. Yu C. R. Chen J. G. Yu C. Y. ( 2014 ). Effect of Schisandra chinensis lignans on neuronal apoptosis and p-AKT expression of rats in cerebral ischemia injury model . Zhongguo Zhong Yao Za Zhi , 39 , 1680 – 1684 . 25095384 

25. Joshi G. Johnson J. A. ( 2012 ). The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases . Recent Pat. CNS Drug Discov. 7 , 218 – 229 . 10.2174/157488912803252023 22742419 

    상세보기

26. Juge N. Mithen R. F. Traka M. ( 2007 ). Molecular basis for chemoprevention by sulforaphane: a comprehensive review . Cell. Mol. Life Sci. 64 , 1105 – 1127 . 10.1007/s00018-007-6484-5 17396224 

    상세보기

27. Khoshnan A. Ko J. Watkin E. E. Paige L. A. Reinhart P. H. Patterson P. H. ( 2004 ). Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity . J. Neurosci. 24 , 7999 – 8008 . 10.1523/JNEUROSCI.2675-04.2004 15371500 

    상세보기

28. Kim M. H. Choi Y. Y. Han J. M. Lee H. S. Hong S. B. Lee S. G. . ( 2014 ). Ameliorative effects of Schizandra chinensis on osteoporosis via activation of estrogen receptor (ER)-α/-β . Food Funct. 5 , 1594 – 1601 . 10.1039/C4FO00133H 24881676 

    상세보기

29. Kumar P. Kumar A. ( 2009 ). Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain . Prog. Neuropsychopharmacol. Biol. Psychiatry 33 , 100 – 108 . 10.1016/j.pnpbp.2008.10.013 19022325 

    상세보기

30. Lam P. Y. Yan C. W. Chiu P. Y. Leung H. Y. Ko K. M. ( 2011 ). Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue . Fitoterapia 82 , 393 – 400 . 10.1016/j.fitote.2010.11.018 21111034 

    상세보기

31. Landis S. C. Amara S. G. Asadullah K. Austin C. P. Blumenstein R. Bradley E. W. . ( 2012 ). A call for transparent reporting to optimize the predictive value of preclinical research . Nature 490 , 187 – 191 . 10.1038/nature11556 23060188 

    상세보기

32. Liu W. Liu Y. Wang Z. Yu T. Lu Q. Chen H. ( 2015 ). Suppression of MAPK and NF-kappa B pathways by schisandrin B contributes to attenuation of DSS-induced mice model of inflammatory bowel disease . Pharmazie 70 , 598 – 603 . 10.1691/ph.2015.5561 26492645 

    

33. Lobsiger C. S. Cleveland D. W. ( 2007 ). Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease . Nat. Neurosci. 10 , 1355 – 1360 . 10.1038/nn1988 17965655 

    상세보기

34. Lu Y. Chen D. F. ( 2009 ). Analysis of Schisandra chinensis and Schisandra sphenanthera . J. Chromatogr. A 1216 , 1980 – 1990 . 10.1016/j.chroma.2008.09.070 18849034 

    상세보기

35. Mahdy H. M. Tadros M. G. Mohamed M. R. Karim A. M. Khalifa A. E. ( 2011 ). The effect of Ginkgo biloba extract on 3-nitropropionic acid-induced neurotoxicity in rats . Neurochem. Int. 59 , 770 – 778 . 10.1016/j.neuint.2011.07.012 21827809 

    상세보기

36. Mao X. Liao Z. Guo L. Xu X. Wu B. Xu M. ( 2015 ). Schisandrin C ameliorates learning and memory deficits by abeta -induced oxidative stress and neurotoxicity in mice . Phytother. Res. 29 , 1373 – 1380 . 10.1002/ptr.5390 

    상세보기

37. Mehrotra A. Sandhir R. ( 2014 ). Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation . Behav. Brain Res. 261 , 345 – 355 . 10.1016/j.bbr.2013.12.035 24393741 

    상세보기

38. Memet S. ( 2006 ). NF-κB functions in the nervous system: from development to disease . Biochem. Pharmacol. 72 , 1180 – 1195 . 10.1016/j.bcp.2006.09.003 16997282 

    상세보기

39. Oh S. Y. Kim Y. H. Bae D. S. Um B. H. Pan C. H. Kim C. Y. . ( 2010 ). Anti-inflammatory effects of gomisin N, gomisin J, and schisandrin C isolated from the fruit of Schisandra chinensis . Biosci. Biotechnol. Biochem. 74 , 285 – 291 . 10.1271/bbb.90597 20139628 

    상세보기

40. Panossian A. Wikman G. ( 2008 ). Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine . J. Ethnopharmacol. 118 , 183 – 212 . 10.1016/j.jep.2008.04.020 18515024 

    상세보기

41. Park S. Y. Park S. J. Park T. G. Rajasekar S. Lee S. J. Choi Y. W. ( 2013 ). Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microglia . Int. Immunopharmacol. 17 , 415 – 426 . 10.1016/j.intimp.2013.06.032 23859871 

    상세보기

42. Pavese N. Gerhard A. Tai Y. F. Ho A. K. Turkheimer F. Barker R. A. . ( 2006 ). Microglial activation correlates with severity in Huntington disease: a clinical and PET study . Neurology 66 , 1638 – 1643 . 10.1212/01.wnl.0000222734.56412.17 16769933 

    상세보기

43. Reagan-Shaw S. Nihal M. Ahmad N. ( 2008 ). Dose translation from animal to human studies revisited . FASEB J. 22 , 659 – 661 . 10.1096/fj.07-9574LSF 17942826 

    상세보기

44. Ross C. A. Tabrizi S. J. ( 2011 ). Huntington's disease: from molecular pathogenesis to clinical treatment . Lancet Neurol. 10 , 83 – 98 . 10.1016/S1474-4422(10)70245-3 21163446 

    상세보기

45. Sandberg M. Patil J. D'Angelo B. Weber S. G. Mallard C. ( 2014 ). NRF2-regulation in brain health and disease: implication of cerebral inflammation . Neuropharmacology 79 , 298 – 306 . 10.1016/j.neuropharm.2013.11.004 24262633 

    상세보기

46. Shi Y. M. Li X. Y. Li X. N. Luo X. Xue Y. B. Liang C. Q. . ( 2011 ). Schicagenins A-C: three cagelike nortriterpenoids from leaves and stems of Schisandra chinensis . Org. Lett. 13 , 3848 – 3851 . 10.1021/ol201366d 21714531 

    상세보기

47. Song Q. Y. Jiang K. Zhao Q. Q. Gao K. Jin X. J. Yao X. J. ( 2013 ). Eleven new highly oxygenated triterpenoids from the leaves and stems of Schisandra chinensis . Org. Biomol. Chem. 11 , 1251 – 1258 . 10.1039/c2ob27115j 23318468 

    상세보기

48. Sugino T. Nozaki K. Hashimoto N. ( 2000 ). Activation of mitogen-activated protein kinases in gerbil hippocampus with ischemic tolerance induced by 3-nitropropionic acid . Neurosci. Lett. 278 , 101 – 104 . 10.1016/S0304-3940(99)00906-4 10643811 

    상세보기

49. Suzuki T. Motohashi H. Yamamoto M. ( 2013 ). Toward clinical application of the Keap1-Nrf2 pathway . Trends Pharmacol. Sci. 34 , 340 – 346 . 10.1016/j.tips.2013.04.005 23664668 

    상세보기

50. Tarozzi A. Angeloni C. Malaguti M. Morroni F. Hrelia S. Hrelia P. ( 2013 ). Sulforaphane as a potential protective phytochemical against neurodegenerative diseases . Oxid. Med. Cell. Longev. 2013 : 415078 . 10.1155/2013/415078 23983898 

    상세보기

51. Thandavarayan R. A. Giridharan V. V. Arumugam S. Suzuki K. Ko K. M. Krishnamurthy P. . ( 2015 ). Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling . PLoS ONE 10 : e0119214 . 10.1371/journal.pone.0119214 25742619 

    상세보기

52. Tunez I. Tasset I. Perez-De La Cruz V. Santamaria A. ( 2010 ). 3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: past, present and future . Molecules 15 , 878 – 916 . 10.3390/molecules15020878 20335954 

    상세보기

53. Wang K. P. Bai Y. Wang J. Zhang J. Z. ( 2014 ). Inhibitory effects of Schisandra chinensis on acetaminophen-induced hepatotoxicity . Mol. Med. Rep. 9 , 1813 – 1819 . 10.3892/mmr.2014.2004 24604262 

    상세보기

54. Wang X. Hu D. Zhang L. Lian G. Zhao S. Wang C. . ( 2014 ). Gomisin A inhibits lipopolysaccharide-induced inflammatory responses in N9 microglia via blocking the NF-kappaB/MAPKs pathway . Food Chem. Toxicol. 63 , 119 – 127 . 10.1016/j.fct.2013.10.048 24211520 

    상세보기

55. Wild E. J. Tabrizi S. J. ( 2014 ). Targets for future clinical trials in Huntington's disease: what's in the pipeline? Mov. Disord. 29 , 1434 – 1445 . 10.1002/mds.26007 25155142 

    상세보기

56. Young Park J. Wook Yun J. Whan Choi Y. Ung Bae J. Won Seo K. Jin Lee S. . ( 2012 ). Antihypertensive effect of gomisin A from Schisandra chinensis on angiotensin II-induced hypertension via preservation of nitric oxide bioavailability . Hypertens. Res. 35 , 928 – 934 . 10.1038/hr.2012.50 22534517 

    상세보기

57. Zeng K. W. Zhang T. Fu H. Liu G. X. Wang X. M. ( 2012 ). Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-kappaB signaling pathway in lipopolysaccharide-induced microglia . Eur. J. Pharmacol. 692 , 29 – 37 . 10.1016/j.ejphar.2012.05.030 22698579 

    상세보기

58. Zhang L. Q. Sa F. Chong C. M. Wang Y. Zhou Z. Y. Chang R. C. . ( 2015 ). Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3beta pathways . J. Ethnopharmacol. 170 , 8 – 15 . 10.1016/j.jep.2015.04.040 25934514 

    상세보기

59. Zheng L. S. Du S. S. Cai Q. ( 2014 ). Study on chemical constituents from Schisandra chinensis stem . Zhong Yao Cai 37 , 1803 – 1806 . 25895389 

    상세보기

60. Zhou E. Li Y. Wei Z. Fu Y. Lei H. Zhang N. . ( 2014 ). Schisantherin A protects lipopolysaccharide-induced acute respiratory distress syndrome in mice through inhibiting NF-kappaB and MAPKs signaling pathways . Int. Immunopharmacol. 22 , 133 – 140 . 10.1016/j.intimp.2014.06.004 24975658 

    상세보기

61. Zhu L. Li B. Liu X. Huang G. Meng X. ( 2015 ). Purification of six lignans from the stems of Schisandra chinensis by using high-speed counter-current chromatography combined with preparative high-performance liquid chromatography . Food Chem. 186 , 146 – 152 . 10.1016/j.foodchem.2014.09.008 25976804 

    상세보기