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NTIS 바로가기Yonsei medical journal, v.59 no.4, 2018년, pp.463 - 469
Yoon, Joo-Heon (Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea .) , Ryu, Junsun (Department of Otolaryngology-Head and Neck Surgery, Center for Thyroid Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea .) , Baek, Seung Joon (Laboratory of Signal Transduction, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea .)
Moonlighting proteins exhibit multiple activities in different cellular compartments, and their abnormal regulation could play an important role in many diseases. To date, many proteins have been identified with moonlighting activity, and more such proteins are being gradually identified. Among the ...
1 Smith LM Kelleher NL Consortium for Top Down Proteomics Proteoform: a single term describing protein complexity Nat Methods 2013 10 186 187 23443629
2 Muñoz J Heck AJ From the human genome to the human proteome Angew Chem Int Ed Engl 2014 53 10864 10866 25079383
3 Jeffery CJ Moonlighting proteins--an update Mol Biosyst 2009 5 345 350 19396370
4 Copley SD Moonlighting is mainstream: paradigm adjustment required Bioessays 2012 34 578 588 22696112
5 Henderson B Martin A Bacterial virulence in the moonlight: multitasking bacterial moonlighting proteins are virulence determinants in infectious disease Infect Immun 2011 79 3476 3491 21646455
6 Kainulainen V Korhonen TK Dancing to another tune-adhesive moonlighting proteins in bacteria Biology (Basel) 2014 3 178 204 24833341
7 Min KW Lee SH Baek SJ Moonlighting proteins in cancer Cancer Lett 2016 370 108 116 26499805
8 Shacter E Weitzman SA Chronic inflammation and cancer Oncology (Williston Park) 2002 16 217 226 11866137
9 Akiyama H Barger S Barnum S Bradt B Bauer J Cole GM Inflammation and Alzheimer's disease Neurobiol Aging 2000 21 383 421 10858586
10 Kuzan A Thymosin β as an actin-binding protein with a variety of functions Adv Clin Exp Med 2016 25 1331 1336 28028989
11 Jain AK Moore SM Yamaguchi K Eling TE Baek SJ Selective nonsteroidal anti-inflammatory drugs induce thymosin beta-4 and alter actin cytoskeletal organization in human colorectal cancer cells J Pharmacol Exp Ther 2004 311 885 891 15292456
12 Lee SI Yi JK Bae WJ Lee S Cha HJ Kim EC Thymosin beta-4 suppresses osteoclastic differentiation and inflammatory responses in human periodontal ligament cells PLoS One 2016 11 e0146708 26789270
13 Conte E Genovese T Gili E Esposito E Iemmolo M Fruciano M Protective effects of thymosin β4 in a mouse model of lung fibrosis Ann N Y Acad Sci 2012 1269 69 73 23045972
14 Bao W Ballard VL Needle S Hoang B Lenhard SC Tunstead JR Cardioprotection by systemic dosing of thymosin beta four following ischemic myocardial injury Front Pharmacol 2013 4 149 24348421
15 Bock-Marquette I Saxena A White MD Dimaio JM Srivastava D Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair Nature 2004 432 466 472 15565145
16 Goldstein AL Kleinman HK Advances in the basic and clinical applications of thymosin β4 Expert Opin Biol Ther 2015 15 Suppl 1 S139 S145 26096726
17 Piludu M Piras M Pichiri G Coni P Orrù G Cabras T Thymosin beta 4 may translocate from the cytoplasm in to the nucleus in HepG2 cells following serum starvation. An ultrastructural study PLoS One 2015 10 e0119642 25835495
18 Huff T Rosorius O Otto AM Müller CS Ballweber E Hannappel E Nuclear localisation of the G-actin sequestering peptide thymosin beta4 J Cell Sci 2004 117 Pt 22 5333 5341 15466884
19 Santra M Zhang ZG Yang J Santra S Chopp M Thymosin β4 up-regulation of microRNA-146a promotes oligodendrocyte differentiation and suppression of the Toll-like proin flammatory pathway J Biol Chem 2014 289 19508 19518 24828499
20 Shen XZ Bernstein KE The peptide network regulated by angiotensin converting enzyme (ACE) in hematopoiesis Cell Cycle 2011 10 1363 1369 21441775
22 Chrysovergis K Wang X Kosak J Lee SH Kim JS Foley JF NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism Int J Obes (Lond) 2014 38 1555 1564 24531647
23 Bootcov MR Bauskin AR Valenzuela SM Moore AG Bansal M He XY MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily Proc Natl Acad Sci U S A 1997 94 11514 11519 9326641
24 Detmer K Steele TA Shoop MA Dannawi H Lineage-restricted expression of bone morphogenetic protein genes in human hematopoietic cell lines Blood Cells Mol Dis 1999 25 310 323 10660478
25 Baek SJ Kim JS Moore SM Lee SH Martinez J Eling TE Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein Mol Pharmacol 2005 67 356 364 15509713
26 Baek SJ Kim KS Nixon JB Wilson LC Eling TE Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities Mol Pharmacol 2001 59 901 908 11259636
27 Baek SJ Wilson LC Eling TE Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53 Carcinogenesis 2002 23 425 434 11895857
28 Li PX Wong J Ayed A Ngo D Brade AM Arrowsmith C Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression J Biol Chem 2000 275 20127 20135 10777512
29 Tan M Wang Y Guan K Sun Y PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway Proc Natl Acad Sci U S A 2000 97 109 114 10618379
30 Cekanova M Lee SH Donnell RL Sukhthankar M Eling TE Fischer SM Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice Cancer Prev Res (Phila) 2009 2 450 458 19401523
31 Kim JM Kosak JP Kim JK Kissling G Germolec DR Zeldin DC NAG-1/GDF15 transgenic mouse has less white adipose tissue and a reduced inflammatory response Mediators Inflamm 2013 2013 641851 23737651
32 Min KW Liggett JL Silva G Wu WW Wang R Shen RF NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway Oncogene 2016 35 377 388 25893289
33 Emmerson PJ Wang F Du Y Liu Q Pickard RT Gonciarz MD The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL Nat Med 2017 23 1215 1219 28846098
34 Hsu JY Crawley S Chen M Ayupova DA Lindhout DA Higbee J Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15 Nature 2017 550 255 259 28953886
35 Mullican SE Lin-Schmidt X Chin CN Chavez JA Furman JL Armstrong AA GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates Nat Med 2017 23 1150 1157 28846097
36 Yang L Chang CC Sun Z Madsen D Zhu H Padkjær SB GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand Nat Med 2017 23 1158 1166 28846099
37 D'Cunha J Knight E Jr Haas AL Truitt RL Borden EC Immunoregulatory properties of ISG15, an interferon-induced cytokine Proc Natl Acad Sci U S A 1996 93 211 215 8552607
38 Speer SD Li Z Buta S Payelle-Brogard B Qian L Vigant F ISG15 deficiency and increased viral resistance in humans but not mice Nat Commun 2016 7 11496 27193971
39 Dos Santos PF Van Weyenbergh J Delgobo M Oliveira Patricio D Ferguson BJ Guabiraba R ISG15-induced IL-10 is a novel anti-inflammatory myeloid axis disrupted during active tuberculosis J Immunol 2018 200 1434 1442 29311364
40 Jeon YJ Yoo HM Chung CH ISG15 and immune diseases Biochim Biophys Acta 2010 1802 485 496 20153823
41 Malakhova OA Zhang DE ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral response J Biol Chem 2008 283 8783 8787 18287095
42 González-Sanz R Mata M Bermejo-Martín J álvarez A Cortijo J Melero JA ISG15 is upregulated in respiratory syncytial virus infection and reduces virus growth through protein ISGylation J Virol 2016 90 3428 3438 26763998
43 Zhang X Bogunovic D Payelle-Brogard B Francois-Newton V Speer SD Yuan C Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation Nature 2015 517 89 93 25307056
44 Shapiro SD Kobayashi DK Ley TJ Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages J Biol Chem 1993 268 23824 23829 8226919
45 Liu SL Bae YH Yu C Monslow J Hawthorne EA Castagnino P Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening Sci Rep 2015 5 17189 26608672
46 Molet S Belleguic C Lena H Germain N Bertrand CP Shapiro SD Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease Inflamm Res 2005 54 31 36 15723202
47 Niu H Li Y Li H Chi Y Zhuang M Zhang T Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity Sci Rep 2016 6 20171 26822129
48 Nénan S Boichot E Lagente V Bertrand CP Macrophage elastase (MMP-12): a pro-inflammatory mediator? Mem Inst Oswaldo Cruz 2005 100 Suppl 1 167 172 15962117
49 Wang X Liang J Koike T Sun H Ichikawa T Kitajima S Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits Am J Pathol 2004 165 1375 1383 15466401
50 Marchant DJ Bellac CL Moraes TJ Wadsworth SJ Dufour A Butler GS A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity Nat Med 2014 20 493 502 24784232
51 Zittermann SI Issekutz AC Basic fibroblast growth factor (bFGF, FGF-2) potentiates leukocyte recruitment to inflammation by enhancing endothelial adhesion molecule expression Am J Pathol 2006 168 835 846 16507899
52 Kanazawa S Tsunoda T Onuma E Majima T Kagiyama M Kikuchi K VEGF, basic-FGF, and TGF-beta in Crohn’s disease and ulcerative colitis: a novel mechanism of chronic intestinal inflammation Am J Gastroenterol 2001 96 822 828 11280558
53 Shao X Chen S Yang D Cao M Yao Y Wu Z FGF2 cooperates with IL-17 to promote autoimmune inflammation Sci Rep 2017 7 7024 28765647
54 Arese M Chen Y Florkiewicz RZ Gualandris A Shen B Rifkin DB Nuclear activities of basic fibroblast growth factor: potentiation of low-serum growth mediated by natural or chimeric nuclear localization signals Mol Biol Cell 1999 10 1429 1444 10233154
55 Ader I Muller C Bonnet J Favre G Cohen-Jonathan E Salles B The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit Oncogene 2002 21 6471 6479 12226750
56 Li S Payne S Wang F Claus P Su Z Groth J Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance Breast Cancer Res 2015 17 91 26141457
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