[논문]Gait Complexity and Regularity Are Differently Modulated by Treadmill Walking in Parkinson's Disease and Healthy Population

Warlop, Thibault; Detrembleur, Christine; Stoquart, Gaë; tan; Lejeune, Thierry; Jeanjean, Anne

doi:10.3389/fphys.2018.00068

Gait Complexity and Regularity Are Differently Modulated by Treadmill Walking in Parkinson's Disease and Healthy Population 원문보기

Frontiers in physiology, v.9, 2018년, pp.68 -

Warlop, Thibault (Physical and Rehabilitation Medicine Department, Cliniques Universitaires Saint-Luc , Brussels , Belgium) , Detrembleur, Christine (Neuro Musculo Skeletal Lab, Institut de Recherche Expé) , Stoquart, Gaëtan (rimentale et Clinique, Université) , Lejeune, Thierry (Catholique de Louvain , Brussels , Belgium) , Jeanjean, Anne (Physical and Rehabilitation Medicine Department, Cliniques Universitaires Saint-Luc , Brussels , Belgium)

Abstract ▼ AI-Helper

Variability raises considerable interest as a promising and sensitive marker of dysfunction in physiology, in particular in neurosciences. Both internally (e.g., pathology) and/or externally (e.g., environment) generated perturbations and the neuro-mechanical responses to them contribute to the fluctuating dynamics of locomotion. Defective internal gait control in Parkinson's disease (PD), resulting in typical timing gait disorders, is characterized by the breakdown of the temporal organization of stride duration variability. Influence of external cue on gait pattern could be detrimental or advantageous depending on situations (healthy or pathological gait pattern, respectively). As well as being an interesting rehabilitative approach in PD, treadmills are usually implemented in laboratory settings to perform instrumented gait analysis including gait variability assessment. However, possibly acting as an external pacemaker, treadmill could modulate the temporal organization of gait variability of PD patients which could invalidate any gait variability assessment. This study aimed to investigate the immediate influence of treadmill walking (TW) on the temporal organization of stride duration variability in PD and healthy population. Here, we analyzed the gait pattern of 20 PD patients and 15 healthy age-matched subjects walking on overground and on a motorized-treadmill (randomized order) at a self-selected speed. The temporal organization and regularity of time series of walking were assessed on 512 consecutive strides and assessed by the application of non-linear mathematical methods (i.e., the detrended fluctuation analysis and power spectral density; and sample entropy, for the temporal organization and regularity of gait variability, respectively). A more temporally organized and regular gait pattern seems to emerge from TW in PD while no influence was observed on healthy gait pattern. Treadmill could afford the necessary framework to regulate gait rhythmicity in PD. Overall, the results support the hypothesis of a greater dependence to regulatory inputs as an explanatory factor of treadmill influence observed in PD. Also, since treadmill misrepresents the gait as more healthy than it is, the present findings underline that gait analysis using treadmill devices should be cautiously considered in PD and especially for gait variability assessment in gait lab.

주제어

참고문헌 (58)

Aaslund M. K. Moe-Nilssen R. ( 2008 ). Treadmill walking with body weight support. Effect of treadmill, harness and body weight support systems. Gait Posture 28 , 303 – 308 . 10.1016/j.gaitpost.2008.01.011 18343664

상세보기
Andriacchi T. Ogle J. Galante J. ( 1977 ). Walking speed as a basis for normal and abnormal gait measurements . J. Biomech. 10 , 261 – 268 . 10.1016/0021-9290(77)90049-5 858732

상세보기
Baker K. Rochester L. Nieuwboer A. ( 2007 ). The immediate effect of attentional, auditory, and a combined cue strategy on Gait during single and dual tasks in Parkinson's disease . Arch. Phys. Med. Rehabil. 88 , 1593 – 1600 . 10.1016/j.apmr.2007.07.026 18047873

상세보기
Balash Y. Hadar-Frumer M. Herman T. Peretz C. Giladi N. Hausdorff J. M. ( 2007 ). The effects of reducing fear of falling on locomotion in older adults with a higher level gait disorder . J. Neural. Transm . 114 , 1309 – 1314 . 10.1007/s00702-007-0771-z 17576513

상세보기
Bayat R. Barbeau H. Lamontagne A. ( 2005 ). Speed and temporal-distance adaptations during treadmill and overground walking following stroke . Neurorehabil. Neural. Repair . 19 , 115 – 124 . 10.1177/1545968305275286 15883355

상세보기
Bello O. Fernandez-Del-Olmo M. ( 2012 ). How does the treadmill affect gait in Parkinson's disease? Curr. Aging Sci. 5 , 28 – 34 . 10.2174/1874609811205010028 21762092
Bello O. Marquez G. Camblor M. Fernandez-Del-Olmo M. ( 2010 ). Mechanisms involved in treadmill walking improvements in Parkinson's disease . Gait Posture 32 , 118 – 123 . 10.1016/j.gaitpost.2010.04.015 20452773

상세보기
Bohnsack-McLagan N. K. Cusumano J. P. Dingwell J. B. ( 2016 ). Adaptability of stride-to-stride control of stepping movements in human walking . J. Biomech. 49 , 229 – 237 . 10.1016/j.jbiomech.2015.12.010 26725217

상세보기
Bollens B. Crevecoeur F. Detrembleur C. Guillery E. Lejeune T. ( 2012 ). Effects of age and walking speed on long-range autocorrelations and fluctuation magnitude of stride duration . Neuroscience 210 , 234 – 242 . 10.1016/j.neuroscience.2012.02.039 22421102

상세보기
Bollens B. Crevecoeur F. Detrembleur C. Warlop T. Lejeune T. M. ( 2014 ). Variability of human gait: effect of backward walking and dual-tasking on the presence of long-range autocorrelations . Ann. Biomed. Eng. 42 , 742 – 750 . 10.1007/s10439-013-0961-9 24366525

상세보기
Bollens B. Crevecoeur F. Nguyen V. Detrembleur C. Lejeune T. ( 2010 ). Does human gait exhibit comparable and reproducible long-range autocorrelations on level ground and on treadmill? Gait Posture 32 , 369 – 373 . 10.1016/j.gaitpost.2010.06.011 20637627

상세보기
Chang M. D. Shaikh S. Chau T. ( 2009 ). Effect of treadmill walking on the stride interval dynamics of human gait . Gait Posture 30 , 431 – 435 . 10.1016/j.gaitpost.2009.06.017 19656682

상세보기
Chien J. H. Ambati P. Huang C.-K. Mukherjee M. ( 2017 ). Tactile stimuli affect long-range correlations of stride interval and stride length differently during walking . Exp. Brain Res. 235 , 1185 – 1193 . 10.1007/s00221-017-4881-z 28188327

상세보기
Crevecoeur F. Bollens B. Detrembleur C. Lejeune T. M. ( 2010 ). Towards a “gold-standard” approach to address the presence of long-range auto-correlation in physiological time series . J. Neurosci. Methods 192 , 163 – 172 . 10.1016/j.jneumeth.2010.07.017 20654647

상세보기
Damouras S. Chang M. D. Sejdić E. Chau T. ( 2010 ). An empirical examination of detrended fluctuation analysis for gait data . Gait Posture 31 , 336 – 340 . 10.1016/j.gaitpost.2009.12.002 20060298

상세보기
Decker L. M. Cignetti F. Stergiou N. ( 2012 ). Wearing a safety harness during treadmill walking influences lower extremity kinematics mainly through changes in ankle regularity and local stability . J. Neuroeng. Rehabil. 9 , 1 – 8 . 10.1186/1743-0003-9-8 22244362

상세보기
Delignieres D. Marmelat V. ( 2012 ). Fractal fluctuations and complexity : current debates and future challenges . Crit. Rev. Biomed. Eng. 40 , 485 – 500 . 10.1615/CritRevBiomedEng.2013006727 23356693

상세보기
Delignieres D. Ramdani S. Lemoine L. Torre K. Fortes M. Ninot G. ( 2006 ). Fractal analyses for “short” time series: a re-assessment of classical methods . J. Math Psych. 50 , 525 – 544 . 10.1016/j.jmp.2006.07.004

상세보기
Dingwell J. B. John J. Cusumano J. P. ( 2010 ). Do humans optimally exploit redundancy to control step variability in walking? PLoS Comput. Biol. 6 , 1 – 14 . 10.1371/journal.pcbi.1000856 20657664

상세보기
Diniz A. Wijnants M. L. Torre K. Barreiros J. Crato N. Bosman A. M. T. . ( 2011 ). Contemporary theories of 1/f noise in motor control . Hum. Mov. Sci. 30 , 889 – 905 . 10.1016/j.humov.2010.07.006 21196059

상세보기
Dotov D. G. Bayard S. Cochen de Cock V. Geny C. Driss V. Garrigue G. . ( 2017 ). Biologically-variable rhythmic auditory cues are superior to isochronous cues in fostering natural gait variability in Parkinson's disease . Gait Posture 51 , 64 – 69 . 10.1016/j.gaitpost.2016.09.020 27710836

상세보기
Fortune E. Lugade V. Morrow M. Kaufman K. ( 2014 ). Validity of using tri-axial accelerometers to measure human movement – part II: step counts at a wide range of gait velocities . Med. Eng. Phys. 36 , 659 – 669 . 10.1016/j.medengphy.2014.02.006 24656871

상세보기
Frenkel-Toledo S. Giladi N. Peretz C. Herman T. Gruendlinger L. Hausdorff J. M. ( 2005 ). Treadmill walking as an external pacemaker to improve gait rhythm and stability in Parkinson's disease . Mov. Disord. 20 , 1109 – 1114 . 10.1002/mds.20507 15929090

상세보기
Gerton B. Theeler B. Samii A. ( 2010 ). Backpack treatment for camptocormia . Mov. Disord. 25 , 247 – 248 . 10.1002/mds.22909 20077473

상세보기
Gilden D. L. Thornton T. Mallon M. W. ( 1995 ). 1/f noise in human cognition . Science 267 , 1837 – 1839 . 10.1126/science.7892611 7892611

상세보기
Hausdorff J. ( 2009 ). Gait dynamics in Parkinson's disease : common and distinct behavior among stride length, gait variability, and fractal-like scaling . Chaos 19 , 1 – 14 . 10.1063/1.3147408 19566273

상세보기
Hausdorff J. M. Lertratanakul A. Cudkowicz M. E. Peterson A. L. Kaliton D. Goldberger A. L. ( 2000 ). Dynamic markers of altered gait rhythm in amyotrophic lateral sclerosis . J. Appl. Physiol. 88 , 2045 – 2053 . 10.1152/jappl.2000.88.6.2045 10846017

상세보기
Hausdorff J. M. Mitchell S. L. Firtion R. Peng C. K. Cudkowicz M. E. Wei J. Y. . ( 1997 ). Altered fractal dynamics of gait : reduced stride-interval correlations with aging and Huntington's disease . J. Appl. Physiol . 82 , 262 – 269 . 10.1152/jappl.1997.82.1.262 9029225

상세보기
Herman T. Giladi N. Gurevich T. Hausdorff J. M. ( 2005 ). Gait instability and fractal dynamics of older adults with a “cautious” gait: why do certain older adults walk fearfully? Gait Posture 21 , 178 – 185 . 10.1016/j.gaitpost.2004.01.014 15639397

상세보기
Hollman J. H. Watkins M. K. Imhoff A. C. Braun C. E. Akervik K. A. Ness D. K. ( 2016 ). A comparison of variability in spatiotemporal gait parameters between treadmill and overground walking conditions . Gait Posture 43 , 204 – 209 . 10.1016/j.gaitpost.2015.09.024 26481257

상세보기
Hughes A. J. Daniel S. E. Kilford L. Lees A. J. ( 1992 ). Accuracy of clinical diagnosis of idiopathic Parkinson's disease : a clinico-pathological study of 100 cases . J. Neurol. Neurosurg. Psychiatr. 55 , 181 – 184 . 10.1136/jnnp.55.3.181 1564476

상세보기
Hunt N. McGrath D. Stergiou N. ( 2014 ). The influence of auditory-motor coupling on fractal dynamics in human gait . Sci. Rep. 4 : 5879 . 10.1038/srep05879 25080936

상세보기
Kegelmeyer D. A. Parthasarathy S. Kostyk S. K. White S. E. Kloos A. D. ( 2013 ). Assistive devices alter gait patterns in Parkinson disease : advantages of the four-wheeled walker . Gait Posture 38 , 20 – 24 . 10.1016/j.gaitpost.2012.10.027 23237981

상세보기
Kyvelidou A. Kurz M. J. Ehlers J. L. Stergiou N. ( 2008 ). Aging and partial body weight support affects gait variability . J. Neuroeng. Rehabil. 5 , 1 – 11 . 10.1186/1743-0003-5-22 18171465

상세보기
Malatesta D. Simar D. Dauvilliers Y. Candau R. Borrani F. Préfaut C. ( 2003 ) Energy cost of walking gait instability in healthy 65- 80-yr-olds . J. Appl. Physiol . 95 , 2248 – 2256 . 10.1152/japplphysiol.01106.2002 12882986

상세보기
Marmelat V. Delignières D. Torre K. Beek P. J. Daffertshofer A. ( 2014a ). “Human paced” walking : Followers adopt stride time dynamics of leaders . Neurosci. Lett. 564 , 67 – 71 . 10.1016/j.neulet.2014.02.010 24548624

상세보기
Marmelat V. Torre K. Beek P. J. Daffertshofer A. ( 2014b ). Persistent fluctuations in stride intervals under fractal auditory stimulation . PLoS ONE 9 : e91949 . 10.1371/journal.pone.0091949 24651455

상세보기
Mehrholz J. Kugler J. Storch A. Pohl M. Elsner B. Hirsch K. ( 2015 ). Treadmill training for patients with Parkinson's disease (Review) . Cochrane Database Syst. Rev. 1 – 67 . 10.1002/14651858.CD007830.pub3
Nieuwboer A. Kwakkel G. Rochester L. Jones D. van Wegen E. Willems A. M. . ( 2007 ). Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trial . J. Neurol. Neurosurg. Psychiatr. 78 , 134 – 140 . 10.1136/jnnp.200X.097923 17229744

상세보기
Rangarajan G. Ding M. ( 2000 ). Integrated approach to the assessment of long range correlation in time series data . Phys. Rev. E . 61 , 4991 – 5001 . 10.1103/PhysRevE.61.4991 11031542

상세보기
Riva F. Bisi M. C. Stagni R. ( 2014 ). Gait variability and stability measures : Minimum number of strides and within-session reliability . Comput. Biol. Med. 50 , 9 – 13 . 10.1016/j.compbiomed.2014.04.001 24792493

상세보기
Schellenbach M. Lövden M. Verrel J. Krüger A. Lindenberger U. ( 2010 ). Adult age differences in familiarization to treadmill walking within virtual environments . Gait Posture 31 , 295 – 299 . 10.1016/j.gaitpost.2009.11.008 20031413

상세보기
Sinclair J. Hobbs S. J. Protheroe L. Edmundson C. J. Greenhalgh A. ( 2013 ). Determination of gait events using an externally mounted shank accelerometer . J. Appl. Biomech. 29 , 118 – 122 . 10.1123/jab.29.1.118 23462448

상세보기
Snijders A. H. Delval A. Weerdesteyn V. Duysens J. Overeem S. Bloem B. R. ( 2011 ) Walking patterns in Parkinson's disease with and without freezing of gait . Neuroscience 182 , 217 – 224 . 10.1016/j.neuroscience.2011.02.061 21382449

상세보기
Stergiou N. Decker L. M. ( 2011 ). Human movement variability, nonlinear dynamics, and pathology : Is there a connection? Hum. Mov. Sci. 30 , 869 – 888 . 10.1016/j.humov.2011.06.002 21802756

상세보기
Stout R. D. Wittstein M. W. LoJacono C. T. Rhea C. K. ( 2016 ). Gait dynamics when wearing a treadmill safety harness . Gait Posture 44 , 100 – 102 . 10.1016/j.gaitpost.2015.11.012 27004640

상세보기
Terrier P. Dériaz O. ( 2011 ). Kinematic variability, fractal dynamics and local dynamic stability of treadmill walking . J. Neuroeng. Rehabil. 8 , 1 – 13 . 10.1186/1743-0003-8-12 21226898

상세보기
Theiler J. Eubank S. Longtin A. Galdrikian B. Farmer D. ( 1992 ). Testing for nonlinearity in time series: the method of surrogate data . Phys D . 58 , 77 – 94 . 10.1016/0167-2789(92)90102-S

상세보기
Tillerson J. L. Cohen A. D. Philhower J. Miller G. W. Zigmond M. J. Schallert T. ( 2001 ). Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine . J. Neurosci. 21 , 4427 – 4435 . 11404429

상세보기
Van de Putte M. Hagemeister N. St-Onge N. Parent G. de Guise J. A. ( 2006 ). Habituation to treadmill walking . Biomed. Mater. Eng. 16 , 43 – 52 . 16410643

상세보기
van Wegen E. de Goede C. Lim I. Rietberg M. Nieuwboer A. Willems A. . ( 2006 ). The effect of rhythmic somatosensory cueing on gait in patients with Parkinson's disease . J. Neurol. Sci. 248 , 210 – 214 . 10.1016/j.jns.2006.05.034 16780887

상세보기
Vivas J. Arias P. Cudeiro J. ( 2011 ). Aquatic therapy versus conventional land-based therapy for Parkinson's disease : an open-label pilot study . Arch. Phys. Med. Rehabil. 92 , 1202 – 1210 . 10.1016/j.apmr.2011.03.017 21807139

상세보기
Warlop T. Detrembleur C. Bollens B. Stoquart G. Crevecoeur F. Jeanjean A. . ( 2016 ). Temporal organization of stride duration variability as a marker of gait instability in Parkinson's disease . J. Rehabil. Med. 48 , 865 – 871 . 10.2340/16501977-2158 27735982

상세보기
Warlop T. Detrembleur C. Buxes Lopez M. Stoquart G. Lejeune T. Jeanjean A. ( 2017 ). Does nordic walking restore the temporal organization of gait variability in Parkinson's disease? J. Neuroeng. Rehabil. 14 , 1 – 11 . 10.1186/s12984-017-0226-1 28057016

상세보기
Wass E. Taylor N. F. Matsas A. ( 2005 ). Familiarisation to treadmill walking in unimpaired older people . Gait Posture 21 , 72 – 79 . 10.1016/j.gaitpost.2004.01.003 15536036

상세보기
Wijnants M. L. Cox R. F. A. Hasselman F. Bosman A. M. T. Van Orden G. ( 2012 ). A trade-off study revealing nested timescales of constraint . Front. Physiol. 3 : 116 . 10.3389/fphys.2012.00116 22654760

상세보기
Winter D. A. ( 1991 ). The biomechanics and motor control of human gait: normal, elderly and pathological ( Waterloo, ON : University of Waterloo Press ).
Yentes J. M. Hunt N. Schmid K. K. Kaipust J. P. McGrath D. M. Stergiou N. ( 2013 ). The appropriate use of approximate entropy and sample entropy with short data sets . Ann. Biomed. Eng. 41 , 349 – 365 . 10.1007/s10439-012-0668-3 23064819

상세보기

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Gait Complexity and Regularity Are Differently Modulated by Treadmill Walking in Parkinson's Disease and Healthy Population 원문보기

Abstract ▼ AI-Helper

주제어

참고문헌 (58)

이 논문을 인용한 문헌

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

연관된 기능

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트