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Effects of the traditional Chinese medicine baicalein on the viability of random pattern skin flaps in rats 원문보기

Drug design, development and therapy, v.12, 2018년, pp.2267 - 2276  

Lin, Renjin (Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China, zhoukailiang@wmu.edu.cn) ,  Lin, Jinti (Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China, zhoukailiang@wmu.edu.cn) ,  Li, Shihen (Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China, zhoukailiang@wmu.edu.cn) ,  Ding, Jian (Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China, zhoukailiang@wmu.edu.cn) ,  Wu, Hongqiang (Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China, zhoukailiang@wmu.edu.cn) ,  Xiang, Guangheng (Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, C) ,  Li, Shi ,  Huang, Yijia ,  Lin, Dingsheng ,  Gao, Weiyang ,  Kong, Jianzhong ,  Xu, Huazi ,  Zhou, Kailiang

Abstract AI-Helper 아이콘AI-Helper

BackgroundRandom skin flaps are routinely placed during plastic and reconstructive surgery, but the distal areas often develop ischemia and necrosis. Baicalein, a major flavonoid extracted from the traditional Chinese herbal medicine huangqin, Scutellaria baicalensis Georgi, may improve flap viabili...

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참고문헌 (34)

  1. 1 Lee MS Ahmad T Lee J Dual delivery of growth factors with coacervate-coated poly(lactic-co-glycolic acid) nanofiber improves neovascularization ina mouse skin flap model Biomaterials 2017 124 65 77 28188996 

  2. 2 Deheng C Kailiang Z Weidong W Salidroside promotes random skin flap survival in rats by enhancing angiogenesis and inhibiting apoptosis J Reconstr Microsurg 2016 32 8 580 586 27276197 

  3. 3 Douglas B Buchholz RR The blood circulation in pedicle flaps: an accurate test for determining ITS efficiency Ann Surg 1943 117 5 692 709 17858213 

  4. 4 Roh TS Jung BK Yun I Lew DH Kim YS Effect of botulinum toxin A on vasoconstriction and sympathetic neurotransmitters in a murine random pattern skin flap model Wound Repair Regen 2017 25 1 75 85 27997734 

  5. 5 Lin R Chen H Callow D Multifaceted effects of astragaloside IV on promotion of random pattern skin flap survival in rats Am J Transl Res 2017 9 9 4161 4172 28979690 

  6. 6 Cheng L Chen T Li H Effects of Tirofiban on Random Skin Flap Survival in Rats J Reconstr Microsurg 2018 34 2 138 144 28992645 

  7. 7 Sheng L Yang M Li H Transplantation of adipose stromal cells promotes neovascularization of random skin flaps Tohoku J Exp Med 2011 224 3 229 234 21701129 

  8. 8 Cheng CS Chen J Tan HY Scutellaria baicalensis and Cancer Treatment: Recent Progress and Perspectives in Biomedical and Clinical Studies Am J Chin Med 2018 46 1 25 54 29316796 

  9. 9 Chan EWC Wong SK Chan HT Casticin from Vitex species: a short review on its anticancer and anti-inflammatory properties J Integr Med 2018 16 3 147 152 29559215 

  10. 10 Zhu XX Yang L Li YJ Yj L Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis Pharmacol Rep 2013 65 2 410 420 23744425 

  11. 11 Lee SI Kim SY Park KR Kim EC Baicalein Promotes Angiogenesis and Odontoblastic Differentiation via the BMP and Wnt Pathways in Human Dental Pulp Cells Am J Chin Med 2016 44 7 1457 1472 27776430 

  12. 12 Wei N Wei Y Li B Pang L Baicalein promotes neuronal and behavioral recovery after intracerebral hemorrhage via suppressing apoptosis, oxidative stress and neuroinflammation Neurochem Res 2017 42 5 1345 1353 28108850 

  13. 13 Liu C Wu J Xu K Neuroprotection by baicalein in ischemic brain injury involves PTEN/AKT pathway J Neurochem 2010 112 6 1500 1512 20050973 

  14. 14 Kumar M Kasala ER Bodduluru LN Dahiya V Lahkar M Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation Inflamm Res 2016 65 8 613 622 27071824 

  15. 15 Liang W Huang X Chen W The effects of baicalin and baicalein on cerebral ischemia: a review Aging Dis 2017 8 6 850 867 29344420 

  16. 16 Zhou KL Zhang YH Lin DS Tao XY Xu HZ Hz X Effects of calcitriol on random skin flap survival in rats Sci Rep 2016 6 18945 26732750 

  17. 17 Chen L Zhou K Chen H Calcitriol promotes survival of experimental random pattern flap via activation of autophagy Am J Transl Res 2017 9 8 3642 3653 28861155 

  18. 18 Liu A Huang L Fan H Baicalein pretreatment protects against liver ischemia/reperfusion injury via inhibition of NF-κB pathway in mice Int Immunopharmacol 2015 24 1 72 79 25479717 

  19. 19 Chao HM Chuang MJ Liu JH Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1α, VEGF, and MMP-9 and upregulation of HO-1 J Ocul Pharmacol Ther 2013 29 6 539 549 23537149 

  20. 20 van Leyen K Kim HY Lee SR Baicalein and 12/15-lipoxygenase in the ischemic brain Stroke 2006 37 12 3014 3018 17053180 

  21. 21 Saul D Kling JH Kosinsky RL Effect of the lipoxygenase inhibitor baicalein on muscles in ovariectomized rats J Nutr Metab 2016 2016 3703216 28050282 

  22. 22 Miocinovic R Mccabe NP Keck RW In vivo and in vitro effect of baicalein on human prostate cancer cells Int J Oncol 2005 26 1 241 246 15586246 

  23. 23 Harder Y Amon M Erni D Menger MD Evolution of ischemic tissue injury in a random pattern flap: a new mouse model using intravital microscopy J Surg Res 2004 121 2 197 205 15501459 

  24. 24 Aydogan H Gurlek A Parlakpinar H Beneficial effects of caffeic acid phenethyl ester (CAPE) on the ischaemia-reperfusion injury in rat skin flaps J Plast Reconstr Aesthet Surg 2007 60 5 563 568 17399667 

  25. 25 Massberg S Messmer K The nature of ischemia/reperfusion injury Transplant Proc 1998 30 8 4217 4223 9865350 

  26. 26 Song K Zhang M Hu J Methane-rich saline attenuates ischemia/reperfusion injury of abdominal skin flaps in rats via regulating apoptosis level BMC Surg 2015 15 92 26228913 

  27. 27 Wang W Zhou PH Xu CG Cg X Baicalein ameliorates renal interstitial fibrosis by inducing myofibroblast apoptosis invivo and invitro BJU Int 2016 118 1 145 152 26178456 

  28. 28 Xia J He LQ Su X Interventional mechanisms of herbs or herbal extracts on renal interstitial fibrosis J Integr Med 2016 14 3 165 173 27181123 

  29. 29 Liu C Wu J Gu J Baicalein improves cognitive deficits induced by chronic cerebral hypoperfusion in rats Pharmacol Biochem Behav 2007 86 3 423 430 17289131 

  30. 30 Chen YC Chow JM Lin CW Wu CY Shen SC Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6 Toxicol Appl Pharmacol 2006 216 2 263 273 16814338 

  31. 31 Scandalios JG Oxygen Stress and Superoxide Dismutases Plant Physiol 1993 101 1 7 12 12231660 

  32. 32 Esterbauer H Cytotoxicity and genotoxicity of lipid-oxidation products Am J Clin Nutr 1993 57 5 Suppl 779S 786S 8475896 

  33. 33 Larsen BD Rampalli S Burns LE Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks Proc Natl Acad Sci U S A 2010 107 9 4230 4235 20160104 

  34. 34 Slee EA Adrain C Martin SJ Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis J Biol Chem 2001 276 10 7320 7326 11058599 

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