[논문]Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder: findings from a pilot randomized controlled trial for art therapy and music reminiscence activity versus usual care

Mahendran, Rathi; Gandhi, Mihir; Moorakonda, Rajesh Babu; Wong, Jonathan; Kanchi, Madhu Mathi; Fam, Johnson; Rawtaer, Iris; Kumar, Alan Prem; Feng, Lei; Kua, Ee Heok

doi:10.1186/s13063-018-2988-6

Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder: findings from a pilot randomized controlled trial for art therapy and music reminiscence activity versus usual care 원문보기

Trials, v.19 no.1, 2018년, pp.615 -

Mahendran, Rathi (Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore, 119228 Singapore) , Gandhi, Mihir (Department of Biostatistics, Singapore Clinical Research Institute, 31 Biopolis Way, Singapore, Singapore) , Moorakonda, Rajesh Babu (Department of Biostatistics, Singapore Clinical Research Institute, 31 Biopolis Way, Singapore, Singapore) , Wong, Jonathan (Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore, 119228 Singapore) , Kanchi, Madhu Mathi (Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore, Singapore) , Fam, Johnson (Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore, 119228 Singapore) , Rawtaer, Iris (Department of Psychiatry, Sengkang General Hospital, 110 Sengkang East Way, Singapore, Singapore) , Kumar, Alan Prem (Cancer Science Institute) , Feng, Lei , Kua, Ee Heok

Abstract ▼ AI-Helper

BackgroundMild cognitive impairment (MCI) is a phase in cognitive decline when it is still possible to intervene to reverse the decline. Cognitive stimulation delivered through psychosocial interventions provides both psychological intervention and social stimulation to improve cognition. A pilot open-label parallel-arms randomized controlled trial was undertaken to examine the effects of art therapy (AT) and music reminiscence activity (MRA) compared to the control, on the primary outcome of neurocognitive domain assessments in elderly people with MCI.MethodsCommunity-living elderly people with MCI (Petersen’s criteria), assessed for study eligibility, were randomized using a web-based system with equal allocation to two intervention arms: AT (guided viewing of art pieces and production of visual arts) and MRA (listening, and recalling memories related to music) and a control arm (standard care without any intervention). Interventions were led by trained therapists weekly for 3 months, then fortnightly for 6 months. Neurocognitive domains (mean of memory, attention, and visuo-spatial abilities standardized scores), psychological wellbeing (subsyndromal depression and anxiety) and telomere length as a biological marker of cellular ageing, were assessed by intervention-blinded assessors at baseline, 3 months and 9 months.ResultsIn total, 250 people were screened and 68 were randomized and included in the analysis. In the AT arm, neurocognitive domains improved compared to the control arm at 3 months (mean difference (d) = 0.40; 90% CI 0.126, 0.679) and were sustained at 9 months (d = 0.31; 90% CI 0.068, 0.548). There was some improvement in depression and anxiety at 3 and 9 months and in telomere length at 9 months, but this was not significant. Similar improvements were observed in the MRA arm over the control arm, but they were not significant. There were no intervention-related adverse effects.ConclusionsArt therapy delivered by trained staff as “art as therapy” and “art psychotherapy” may have been the significant contributor to cognitive improvements. The findings support cognitive stimulation for elderly people with cognitive decline and signal the need for larger studies and further investigation of carefully designed psycho-social interventions for this group.Trial registrationClinical Trials.gov, NCT02854085. Registered on 7 July 2016.Electronic supplementary materialThe online version of this article (10.1186/s13063-018-2988-6) contains supplementary material, which is available to authorized users.

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Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder: findings from a pilot randomized controlled trial for art therapy and music reminiscence activity versus usual care 원문보기

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