[논문]VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT: study protocol for a randomized controlled trial (VENUS trial)

Oh, Hyung Jung; An, Jung Nam; Oh, Sohee; Rhee, Harin; Lee, Jung Pyo; Kim, Dong Ki; Ryu, Dong-Ryeol; Kim, Sejoong

doi:10.1186/s13063-018-3056-y

VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT: study protocol for a randomized controlled trial (VENUS trial) 원문보기

Trials, v.19 no.1, 2018년, pp.681 -

Oh, Hyung Jung (Ewha Institute of Convergence Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea) , An, Jung Nam (Department of Critical Care Medicine, Seoul National University Boramae, Medical Center, Seoul, Republic of Korea) , Oh, Sohee (Department of Biostatistics, Seoul National University Boramae, Medical Center, Seoul, Republic of Korea) , Rhee, Harin (Department of Internal Medicine, Pusan National University School of Medicine, Busan, Republic of Korea) , Lee, Jung Pyo (Department of Internal Medicine, Seoul National University Boramae, Medical Center, Seoul, Republic of Korea) , Kim, Dong Ki (Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea) , Ryu, Dong-Ryeol (Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea) , Kim, Sejoong (Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13620 Republic of Korea)

Abstract ▼ AI-Helper

BackgroundDespite recent technical advances in the management of acute kidney injury (AKI), such as continuous renal replacement therapy (CRRT), intensive care unit mortality is still high, at approximately 40 to 50%. Although several factors have been reported to predict mortality in AKI patients, fluid overload (FO) during CRRT is a well-known predictor of patient survival. However, FO has been mostly quantified as an arithmetical calculation and determined on the basis of the physicians’ perception. Even though such quantification and assessment provides an easy evaluation of a patient’s fluid status and is a simple method, it is not applicable unless a detailed record of fluid monitoring is available. Furthermore, the method cannot differentiate excess water in individual water compartments but can only reflect excess total body water. Bioimpedance analysis (BIA) has been used to measure the nutritional component of body composition and is a promising tool for the measurement of volume status. However, there has been no prospective interventional study for fluid balance among CRRT-treated AKI patients using BIA. Therefore, we will investigate the usefulness of fluid management using the InBody S10 (InBody®, Seoul, Korea), a BIA tool, compared with that of generally used quantification methods.Methods/designThis will be a multicenter, prospective, randomized controlled trial. A total of 244 patients undergoing CRRT treatment will be enrolled and randomly assigned to receive either to InBody S10-guided management or to fluid management based only on clinical information for 7 days. The primary outcome is to compare the rate of euvolemic status 7 days after the initiation of CRRT, with a secondary outcome being to compare the 28-, 60-, and 90-day mortality rates between the two groups.DiscussionThis will be the first clinical trial to investigate the effect of using BIA-guided fluid management to achieve euvolemia in CRRT-treated AKI patients.Trial registrationClinicalTrials.gov, ID: NCT03330626. Registered on 6 November 2017.Electronic supplementary materialThe online version of this article (10.1186/s13063-018-3056-y) contains supplementary material, which is available to authorized users.

주제어

참고문헌 (29)

1. Ostermann M Joannidis M Pani A Patient selection and timing of continuous renal replacement therapy Blood Purif 2016 42 224 237 10.1159/000448506 27561956

상세보기
2. Bagshaw SM Chakravarthi MR Ricci Z Precision continuous renal replacement therapy and solute control Blood Purif 2016 42 238 247 10.1159/000448507 27562079

상세보기
3. Murugan R Hoste E Mehta RL Precision fluid management in continuous renal replacement therapy Blood Purif 2016 42 266 278 10.1159/000448528 27562336

상세보기
4. Cerda J Baldwin I Honore PM Villa G Kellum JA Ronco C Role of technology for the management of AKI in critically ill patients: from adoptive technology to precision continuous renal replacement rherapy Blood Purif 2016 42 248 265 10.1159/000448527 27562206

상세보기
5. Ronco C Bellomo R Homel P Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial Lancet 2000 356 26 30 10.1016/S0140-6736(00)02430-2 10892761

상세보기
6. Heering P Morgera S Schmitz FJ Cytokine removal and cardiovascular hemodynamics in septic patients with continuous venovenous hemofiltration Intensive Care Med 1997 23 288 296 10.1007/s001340050330 9083231

상세보기
7. Uchino S Kellum JA Bellomo R Acute renal failure in critically ill patients: a multinational, multicenter study JAMA 2005 294 813 818 10.1001/jama.294.7.813 16106006

상세보기
8. Nisula S Kaukonen KM Vaara ST Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study Intensive Care Med 2013 39 420 428 10.1007/s00134-012-2796-5 23291734

상세보기
9. Oh HJ Kim MH Ahn JY Can early initiation of continuous renal replacement therapy improve patient survival with septic acute kidney injury when enrolled in early goal-directed therapy? J Crit Care 2016 35 51 56 10.1016/j.jcrc.2016.04.032 27481735

상세보기
10. Oh HJ Shin DH Lee MJ Early initiation of continuous renal replacement therapy improves patient survival in severe progressive septic acute kidney injury J Crit Care 2012 27 743.e9 743.18 10.1016/j.jcrc.2012.08.001

상세보기
11. Bagshaw SM Brophy PD Cruz D Ronco C Fluid balance as a biomarker: impact of fluid overload on outcome in critically ill patients with acute kidney injury Crit Care 2008 12 169 10.1186/cc6948 18671831

상세보기
12. Cerda J Sheinfeld G Ronco C Fluid overload in critically ill patients with acute kidney injury Blood Purif 2010 29 331 338 10.1159/000287776 20173320

상세보기
13. Metnitz PG Krenn CG Steltzer H Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients Crit Care Med 2002 30 2051 2058 10.1097/00003246-200209000-00016 12352040

상세보기
14. Neyra JA Li X Canepa-Escaro F Cumulative fluid balance and mortality in septic patients with or without acute kidney injury and chronic kidney disease Crit Care Med 2016 44 1891 1900 10.1097/CCM.0000000000001835 27352125

상세보기
15. Bellomo R Cass A Cole L An observational study fluid balance and patient outcomes in the Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy trial Crit Care Med 2012 40 1753 1760 10.1097/CCM.0b013e318255d9a0 22610181

상세보기
16. Garzotto F Ostermann M Martin-Langerwerf D The Dose Response Multicentre Investigation on Fluid Assessment (DoReMIFA) in critically ill patients Crit Care 2016 20 196 10.1186/s13054-016-1355-9 27334608

상세보기
17. Rhee H Jang KS Shin MJ Use of multifrequency bioimpedance analysis in male patients with acute kidney injury who are undergoing continuous veno-venous hemodiafiltration PLoS One 2015 10 e0133199 10.1371/journal.pone.0133199 26186370

상세보기
18. Kyle UG Unger P Dupertuis YM Karsegard VL Genton L Pichard C Body composition in 995 acutely ill or chronically ill patients at hospital admission: a controlled population study J Am Diet Assoc 2002 102 944 955 10.1016/S0002-8223(02)90216-6 12146557

상세보기
19. Kyle UG Bosaeus I De Lorenzo AD Bioelectrical impedance analysis-part II: utilization in clinical practice Clin Nutr 2004 23 1430 1453 10.1016/j.clnu.2004.09.012 15556267

상세보기
20. Malbrain ML Huygh J Dabrowski W De Waele JJ Staelens A Wauters J The use of bio-electrical impedance analysis (BIA) to guide fluid management, resuscitation and deresuscitation in critically ill patients: a bench-to-bedside review Anaesthesiol Intensive Ther 2014 46 381 391 10.5603/AIT.2014.0061 25432557

상세보기
21. Kyle UG Bosaeus I De Lorenzo AD Bioelectrical impedance analysis—part I: review of principles and methods Clin Nutr 2004 23 1226 1243 10.1016/j.clnu.2004.06.004 15380917

상세보기
22. Chamney PW Wabel P Moissl UM A whole-body model to distinguish excess fluid from the hydration of major body tissues Am J Clin Nutr 2007 85 80 89 10.1093/ajcn/85.1.80 17209181

상세보기
23. O’Lone EL Visser A Finney H Fan SL Clinical significance of multi-frequency bioimpedance spectroscopy in peritoneal dialysis patients: independent predictor of patient survival Nephrol Dial Transplant 2014 29 1430 1437 10.1093/ndt/gfu049 24598280

상세보기
24. Koh KH Wong HS Go KW Morad Z Normalized bioimpedance indices are better predictors of outcome in peritoneal dialysis patients Perit Dial Int 2011 31 574 582 10.3747/pdi.2009.00140 20592100

상세보기
25. Alijanian N Naini AE Shahidi S Liaghat L Samani RR The comparative evaluation of patients’ body dry weight under hemodialysis using two methods: bioelectrical impedance analysis and conventional method J Res Med Sci 2012 17 923 927 23825990
26. Tattersall J Bioimpedance analysis in dialysis: state of the art and what we can expect Blood Purif 2009 27 70 74 10.1159/000167012

상세보기
27. Kotanko P Levin NW Zhu F Current state of bioimpedance technologies in dialysis Nephrol Dial Transplant 2008 23 808 812 10.1093/ndt/gfm889 18182405

상세보기
28. Basso F Berdin G Virzi GM Fluid management in the intensive care unit: bioelectrical impedance vector analysis as a tool to assess hydration status and optimal fluid balance in critically ill patients Blood Purif 2013 36 192 199 10.1159/000356366 24496190

상세보기
29. Dabrowski W Kotlinska-Hasiec E Schneditz D Continuous veno-venous hemofiltration to adjust fluid volume excess in septic shock patients reduces intra-abdominal pressure Clin Nephrol 2014 82 41 50 24887300

상세보기

LOADING...

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT: study protocol for a randomized controlled trial (VENUS trial) 원문보기

Abstract ▼ AI-Helper

주제어

참고문헌 (29)

이 논문을 인용한 문헌

연구과제 타임라인

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT: study protocol for a randomized controlled trial (VENUS trial) 원문보기

Abstract ▼ AI-Helper

주제어

참고문헌 (29)

이 논문을 인용한 문헌

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트