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[해외논문] Therapeutic Effect of Chitooligosaccharide Tablets on Lipids in High-Fat Diets Induced Hyperlipidemic Rats 원문보기

Molecules a journal of synthetic chemistry and natural product chemistry, v.24 no.3, 2019년, pp.514 -   

Yang, Di (Guangdong Engineering Research Center of Natural Products and New Drugs, Guangdong Provincial University Engineering Technology Research Center of Natural Products and Drugs, Guangdong Pharmaceutical University, Guangzhou 510006, China) ,  Hu, Canji (yangdi552@hotmail.com (D.Y.)) ,  Deng, Xiaoyi (hcj7319@163.com (C.H.)) ,  Bai, Yan (dxy1500718043@163.com (X.D.)) ,  Cao, Hua (angell_bai@163.com (Y.B.)) ,  Guo, Jiao (Guangdong Engineering Research Center of Natural Products and New Drugs, Guangdong Provincial University Engineering Technology Research Center of Natural Products and Drugs, Guangdong Pharmaceutical University, Guangzhou 510006, China) ,  Su, Zhengquan (yangdi552@hotmail.com (D.Y.))

Abstract AI-Helper 아이콘AI-Helper

Chitooligosaccharide is beneficial for inhibiting dyslipidemia and reducing atherosclerotic and hyperlipidemic risk. The purpose of this study was to investigate the cholesterol-regulating effects and potential mechanisms of Chitooligosaccharide tablets (CFTs) in high-fat diet-induced hyperlipidemic...

Keyword

참고문헌 (29)

  1. 1. Akiyama T. Tachibana I. Shirohara H. Watanabe N. Otsuki M. High-Fat Hypercaloric Diet Induces Obesity, Glucose Intolerance and Hyperlipidemia in Normal Adult Male Wistar Rat Diabetes Res. Clin. Pract. 1996 31 27 35 10.1016/0168-8227(96)01205-3 8792099 

  2. 2. Parhofer K.G. The Treatment of Disorders of Lipid Metabolism Deutsch. Ärzteblatt Int. 2016 113 261 268 10.3238/arztebl.2016.0261 

  3. 3. Kaur J. A comprehensive review on metabolic syndrome Cardiol. Res. Pract. 2014 2014 943162 10.1155/2014/943162 24711954 

  4. 4. Rutishauser J. The role of statins in clinical medicine–LDL–cholesterol lowering and beyond Swiss Med. Wkly. 2006 136 41 49 16633945 

  5. 5. Muanprasat C. Chatsudthipong V. Chitosan oligosaccharide: Biological activities and potential therapeutic applications Pharmacol. Ther. 2017 170 80 97 10.1016/j.pharmthera.2016.10.013 27773783 

  6. 6. Huang L. Chen J. Cao P. Pan H. Ding C. Xiao T. Zhang P. Guo J. Su Z. Anti-obese effect of glucosamine and chitosan oligosaccharide in high-fat diet-induced obese rats Mar. Drugs 2015 13 2732 2756 10.3390/md13052732 25942093 

  7. 7. Kong S. Ding C. Huang L. Bai Y. Xiao T. Guo J. Su Z. The effects of COST on the differentiation of 3T3-L1 preadipocytes and the mechanism of action Saudi J. Biol. Sci. 2017 24 251 255 10.1016/j.sjbs.2016.09.008 28149159 

  8. 8. Yang Q.Y. Guo J. Su Z.Q. The preparation and the anti-obesity activity of chitosan oligosaccharide film coating tablets Basic Clin. Pharmacol. Toxicol. 2016 119 29 

  9. 9. Chiang J.Y. Bile acids: Regulation of synthesis J. Lipid Res. 2009 50 1955 1966 10.1194/jlr.R900010-JLR200 19346330 

  10. 10. Liu S. Wu Z. Guo S. Meng X. Chang X. Polyphenol-rich extract from wild Lonicera caerulea berry reduces cholesterol accumulation by mediating the expression of hepatic miR-33 and miR-122, HMGCR, and CYP7A1 in rats J. Funct. Foods 2018 40 648 658 10.1016/j.jff.2017.11.048 

  11. 11. Jiao R. Zhang Z. Yu H. Huang Y. Chen Z.Y. Hypocholesterolemic activity of grape seed proanthocyanidin is mediated by enhancement of bile acid excretion and up-regulation of CYP7A1 J. Nutr. Biochem. 2010 21 1134 1139 10.1016/j.jnutbio.2009.10.007 20092993 

  12. 12. Lee J.H. Lee S.Y. Kim B. Seo W.D. Jia Y. Wu C. Jun H.-J. Lee S.-J. Barley sprout extract containing policosanols and polyphenols regulate AMPK, SREBP2 and ACAT2 activity and cholesterol and glucose metabolism in vitro and in vivo Food Res. Int. 2015 72 174 183 10.1016/j.foodres.2015.03.041 

  13. 13. Su Z. Guo J. Yang Q. Chitosan Oligosaccharide Tablet and Preparation Method Thereof Patent No. ZL201510988018.1 24 12 2015 

  14. 14. Lee H.S. Lee Y.J. Chung Y.H. Nam Y. Kim S.T. Park E.S. Hong S.M. Yang Y.K. Kim H.C. Jeong J.H. Beneficial Effects of Red Yeast Rice on High-Fat Diet-Induced Obesity, Hyperlipidemia, and Fatty Liver in Mice J. Med. Food 2015 18 1095 1102 10.1089/jmf.2014.3259 26133037 

  15. 15. Ahangari N. Ghayour Mobarhan M. Sahebkar A. Pasdar A. Molecular aspects of hypercholesterolemia treatment: Current perspectives and hopes Ann. Med. 2018 50 303 311 10.1080/07853890.2018.1457795 29578362 

  16. 16. Wang L. Xu F. Zhang X.J. Jin R.M. Li X. Effect of high-fat diet on cholesterol metabolism in rats and its association with Na(+)/K(+)-ATPase/Src/pERK signaling pathway J. Huazhong Univ. Sci. Technol. Med. Sci. 2015 35 490 494 10.1007/s11596-015-1458-6 26223915 

  17. 17. Niroumand S. Khajedaluee M. Khadem-Rezaiyan M. Abrishami M. Juya M. Khodaee G. Dadgarmoghaddam M. Atherogenic Index of Plasma (AIP): A marker of cardiovascular disease Med. J. Islam. Repub. Iran 2015 29 240 26793631 

  18. 18. Shi F. Li J. Yang L. Hou G. Ye M. Hypolipidemic effect and protection ability of liver-kidney functions of melanin from Lachnum YM226 in high-fat diet fed mice Food Funct. 2018 9 880 889 10.1039/C7FO01294B 29299589 

  19. 19. Mahmoudi A. Hadrich F. Feki I. Ghorbel H. Bouallagui Z. Marrekchi R. Fourati H. Sayadi S. Oleuropein and hydroxytyrosol rich extracts from olive leaves attenuate liver injury and lipid metabolism disturbance in bisphenol A-treated rats Food Funct. 2018 9 3220 3234 10.1039/C8FO00248G 29781491 

  20. 20. Kim W.R. Flamm S.L. Di Bisceglie A.M. Bodenheimer H.C. Public Policy Committee of the American Association for the Study of Liver. Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease Hepatology 2008 47 1363 1370 10.1002/hep.22109 18366115 

  21. 21. Cao P. Huang G. Yang Q. Guo J. Su Z. The effect of chitooligosaccharides on oleic acid-induced lipid accumulation in HepG2 cells Saudi Pharm. J. 2016 24 292 298 10.1016/j.jsps.2016.04.023 27275117 

  22. 22. Musso G. Gambino R. Cassader M. Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis Prog. Lipid Res. 2013 52 175 191 10.1016/j.plipres.2012.11.002 23206728 

  23. 23. Siow H.-L. Choi S.-B. Gan C.-Y. Structure–activity studies of protease activating, lipase inhibiting, bile acid binding and cholesterol-lowering effects of pre-screened cumin seed bioactive peptides J. Funct. Foods 2016 27 600 611 10.1016/j.jff.2016.10.013 

  24. 24. Hylemon P.B. Takabe K. Dozmorov M. Nagahashi M. Zhou H. Bile acids as global regulators of hepatic nutrient metabolism Liver Res. 2017 1 10 16 10.1016/j.livres.2017.03.002 29123941 

  25. 25. Liang Y.T. Chen J. Jiao R. Peng C. Zuo Y. Lei L. Liu Y. Wang X. Ma K.Y. Huang Y. Cholesterol-Lowering Activity of Sesamin Is Associated with Down-Regulation on Genes of Sterol Transporters Involved in Cholesterol Absorption J. Agric. Food Chem. 2015 63 2963 2969 10.1021/jf5063606 25745846 

  26. 26. Zhang D. Tong X. Nelson B.B. Jin E. Sit J. Charney N. Yang M. Omary M.B. Yin L. The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARalpha pathway Hepatology 2018 10.1002/hep.29878 

  27. 27. Madison B.B. Srebp2: A master regulator of sterol and fatty acid synthesis J. Lipid Res. 2016 57 333 335 10.1194/jlr.C066712 26798145 

  28. 28. Song Y. Xu C. Shao S. Liu J. Xing W. Xu J. Qin C. Li C. Hu B. Yi S. Thyroid-stimulating hormone regulates hepatic bile acid homeostasis via SREBP-2/HNF-4alpha/CYP7A1 axis J. Hepatol. 2015 62 1171 1179 10.1016/j.jhep.2014.12.006 25533663 

  29. 29. He K. Li X. Xiao Y. Yong Y. Zhang Z. Li S. Zhou T. Yang D. Gao P. Xin X. Hypolipidemic effects of Myrica rubra extracts and main compounds in C57BL/6j mice Food Funct. 2016 7 3505 3515 10.1039/C6FO00623J 27459037 

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