[논문]Ayres Theories of Autism and Sensory Integration Revisited: What Contemporary Neuroscience Has to Say

Kilroy, Emily; Aziz-Zadeh, Lisa; Cermak, Sharon

doi:10.3390/brainsci9030068

Ayres Theories of Autism and Sensory Integration Revisited: What Contemporary Neuroscience Has to Say 원문보기

Brain sciences, v.9 no.3, 2019년, pp.68 -

Kilroy, Emily (Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy, University Southern California, Los Angeles, CA 90089, USA) , Aziz-Zadeh, Lisa (lazizzad@usc.edu (L.A.-Z.)) , Cermak, Sharon (cermak@usc.edu (S.C.))

Abstract ▼ AI-Helper

Abnormal sensory-based behaviors are a defining feature of autism spectrum disorders (ASD). Dr. A. Jean Ayres was the first occupational therapist to conceptualize Sensory Integration (SI) theories and therapies to address these deficits. Her work was based on neurological knowledge of the 1970’s. Since then, advancements in neuroimaging techniques make it possible to better understand the brain areas that may underlie sensory processing deficits in ASD. In this article, we explore the postulates proposed by Ayres (i.e., registration, modulation, motivation) through current neuroimaging literature. To this end, we review the neural underpinnings of sensory processing and integration in ASD by examining the literature on neurophysiological responses to sensory stimuli in individuals with ASD as well as structural and network organization using a variety of neuroimaging techniques. Many aspects of Ayres’ hypotheses about the nature of the disorder were found to be highly consistent with current literature on sensory processing in children with ASD but there are some discrepancies across various methodological techniques and ASD development. With additional characterization, neurophysiological profiles of sensory processing in ASD may serve as valuable biomarkers for diagnosis and monitoring of therapeutic interventions, such as SI therapy.

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참고문헌 (156)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 5th ed. DSM-5 American Psychiatric Association Philadelphia, PA, USA 2013 978-0-89-042555-8
2. Baio J. Wiggins L. Christensen D.L. Maenner M.J. Daniels J. Warren Z. Kurzius-Spencer M. Zahorodny W. Rosenberg C.R. White T. Prevalence of Autism Spectrum Disorder among Children Aged 8 Years—Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014 MMWR Surveill. Summ. 2018 67 1 23 10.15585/mmwr.ss6706a1

상세보기
3. Geschwind D.H. Advances in Autism Annu. Rev. Med. 2009 60 367 380 10.1146/annurev.med.60.053107.121225 19630577

상세보기
4. Marco E.J. Hinkley L.B.N. Hill S.S. Nagarajan S.S. Sensory Processing in Autism: A Review of Neurophysiologic Findings Pediatr. Res. 2011 69 48R 54R 10.1203/PDR.0b013e3182130c54 21289533

상세보기
5. Jasmin E. Couture M. McKinley P. Reid G. Fombonne E. Gisel E. Sensori-Motor and Daily Living Skills of Preschool Children with Autism Spectrum Disorders J. Autism Dev. Disord. 2009 39 231 241 10.1007/s10803-008-0617-z 18629623

상세보기
6. MacDonald M. Lord C. Ulrich D. The Relationship of Motor Skills and Adaptive Behavior Skills in Young Children with Autism Spectrum Disorders Res. Autism Spectr. Disord. 2013 7 1383 1390 10.1016/j.rasd.2013.07.020 25774214

상세보기
7. Matsushima K. Kato T. Social Interaction and Atypical Sensory Processing in Children with Autism Spectrum Disorders Hong Kong J. Occup. Ther. 2013 23 89 96 10.1016/j.hkjot.2013.11.003

상세보기
8. Ayres J. Sensory integration therapy Sensory Integration and the Child Western Psychological Services Los Angeles, CA, USA 1979 1352156
9. Wing L. Yeates S.R. Brierley L.M. Gould J. The Prevalence of Early Childhood Autism: Comparison of Administrative and Epidemiological Studies Psychol. Med. 1976 6 89 100 10.1017/S0033291700007522 935299

상세보기
10. Ayres A.J. Tickle L.S. Hyper-Responsivity to Touch and Vestibular Stimuli as a Predictor of Positive Response to Sensory Integration Procedures by Autistic Children Am. J. Occup. Ther. 1980 34 375 381 10.5014/ajot.34.6.375 6971048

상세보기
11. Lectures and Speeches (1964–1985), Dr. A Jean Ayres Archive, Collection no. 0317, Special Collections, USC Libraries, University of Southern California Available online: https://archives.usc.edu/repositories/3/resources/2321 (accessed on 20 March 2019)
12. Koegel R.L. Mentis M. Motivation in Childhood Autism: Can They or Won’t They? J. Child Psychol. Psychiatry 1985 26 185 191 10.1111/j.1469-7610.1985.tb02259.x 3884640

상세보기
13. Dawson G. Webb S.J. McPartland J. Understanding the Nature of Face Processing Impairment in Autism: Insights from Behavioral and Electrophysiological Studies Dev. Neuropsychol. 2005 27 403 424 10.1207/s15326942dn2703_6 15843104

상세보기
14. Harms M.B. Martin A. Wallace G.L. Facial Emotion Recognition in Autism Spectrum Disorders: A Review of Behavioral and Neuroimaging Studies Neuropsychol. Rev. 2010 20 290 322 10.1007/s11065-010-9138-6 20809200

상세보기
15. Nair A. Carper R.A. Abbott A.E. Chen C.P. Solders S. Nakutin S. Datko M.C. Fishman I. Müller R.-A. Regional Specificity of Aberrant Thalamocortical Connectivity in Autism Hum. Brain Mapp. 2015 36 4497 4511 10.1002/hbm.22938 26493162

상세보기
16. Gibbard C.R. Ren J. Skuse D.H. Clayden J.D. Clark C.A. Structural Connectivity of the Amygdala in Young Adults with Autism Spectrum Disorder Hum. Brain Mapp. 2018 39 1270 1282 10.1002/hbm.23915 29265723

상세보기
17. Courchesne E. Pierce K. Schumann C.M. Redcay E. Buckwalter J.A. Kennedy D.P. Morgan J. Mapping Early Brain Development in Autism Neuron 2007 56 399 413 10.1016/j.neuron.2007.10.016 17964254

상세보기
18. Buxbaum J.D. Hof P.R. Morgan J.T. Nordahl C.W. Schumann C.M. The Amygdala in Autism Spectrum Disorders Neurosci. Autism Spectr. Disord. 2013 297 312 10.1016/b978-0-12-391924-3.00021-1
19. Pfeiffer B.A. Koenig K. Kinnealey M. Sheppard M. Henderson L. Effectiveness of Sensory Integration Interventions in Children with Autism Spectrum Disorders: A Pilot Study Am. J. Occup. Ther. 2011 65 76 85 10.5014/ajot.2011.09205 21309374

상세보기
20. Schaaf R.C. Hunt J. Benevides T. Occupational Therapy Using Sensory Integration to Improve Participation of a Child with Autism: A Case Report Am. J. Occup. Ther. 2012 66 547 555 10.5014/ajot.2012.004473 22917121

상세보기
21. Schaaf R.C. Benevides T. Mailloux Z. Faller P. Hunt J. van Hooydonk E. Freeman R. Leiby B. Sendecki J. Kelly D. An Intervention for Sensory Difficulties in Children with Autism: A Randomized Trial J. Autism Dev. Disord. 2014 44 1493 1506 10.1007/s10803-014-2111-0 24214165

상세보기
22. Watling R. Hauer S. Effectiveness of Ayres Sensory Integration ® and Sensory-Based Interventions for People with Autism Spectrum Disorder: A Systematic Review Am. J. Occup. Ther. 2015 69 10.5014/ajot.2015.018051

상세보기
23. Kandel E.R. Schwartz J.H. James H. Jessell T.M. Principles of Neural Science Elsevier New York, NY, USA 1991 0838580688
24. Damasio A.R. Emotion in the Perspective of an Integrated Nervous System Brain Res. Rev. 1998 26 83 86 10.1016/S0165-0173(97)00064-7

상세보기
25. Rolls E.T. Limbic Systems for Emotion and For Memory but No Single Limbic System Cortex 2015 62 119 157 10.1016/j.cortex.2013.12.005 24439664

상세보기
26. Herrington J.D. Maddox B.B. Kerns C.M. Rump K. Worley J.A. Bush J.C. McVey A.J. Schultz R.T. Miller J.S. Amygdala Volume Differences in Autism Spectrum Disorder Are Related to Anxiety J. Autism Dev. Disord. 2017 47 3682 3691 10.1007/s10803-017-3206-1 28689329

상세보기
27. Radeloff D. Ciaramidaro A. Siniatchkin M. Hainz D. Schlitt S. Weber B. Poustka F. Bölte S. Walter H. Freitag C.M. Structural Alterations of The Social Brain: A Comparison between Schizophrenia and Autism PLoS ONE 2014 9 e106539 10.1371/journal.pone.0106539 25188200

상세보기
28. Dalton K.M. Nacewicz B.M. Alexander A.L. Davidson R.J. Gaze-Fixation, Brain Activation and Amygdala Volume in Unaffected Siblings of Individuals with Autism Biol. Psychiatry 2007 61 512 520 10.1016/j.biopsych.2006.05.019 17069771

상세보기
29. Libero L.E. Burge W.K. Deshpande H.D. Pestilli F. Kana R.K. White Matter Diffusion of Major Fiber Tracts Implicated in Autism Spectrum Disorder Brain Connect. 2016 6 691 699 10.1089/brain.2016.0442 27555361

상세보기
30. Schumann C.M. Hamstra J. Goodlin-Jones B.L. Lotspeich L.J. Kwon H. Buonocore M.H. Lammers C.R. Reiss A.L. Amaral D.G. The Amygdala Is Enlarged in Children but Not Adolescents with Autism; The Hippocampus Is Enlarged at All Ages J. Neurosci. 2004 24 6392 6401 10.1523/JNEUROSCI.1297-04.2004 15254095

상세보기
31. Xiao Z. Qiu T. Ke X. Xiao X. Xiao T. Liang F. Zou B. Huang H. Fang H. Chu K. Autism Spectrum Disorder as Early Neurodevelopmental Disorder: Evidence from the Brain Imaging Abnormalities in 2–3 Years Old Toddlers J. Autism Dev. Disord. 2014 44 1633 1640 10.1007/s10803-014-2033-x 24419870

상세보기
32. Courchesne E. Campbell K. Solso S. Brain Growth across the Life Span in Autism: Age-Specific Changes in Anatomical Pathology Brain Res. 2011 1380 138 145 10.1016/j.brainres.2010.09.101 20920490

상세보기
33. Schumann C.M. Amaral D.G. Stereological Analysis of Amygdala Neuron Number in Autism J. Neurosci. 2006 26 7674 7679 10.1523/JNEUROSCI.1285-06.2006 16855095

상세보기
34. Aylward E.H. Minshew N.J. Goldstein G. Honeycutt N.A. Augustine A.M. Yates K.O. Barta P.E. Pearlson G.D. MRI Volumes of Amygdala and Hippocampus in Non-Mentally Retarded Autistic Adolescents and Adults Neurology 1999 53 2145 2150 10.1212/WNL.53.9.2145 10599796

상세보기
35. Braden B.B. Smith C.J. Thompson A. Glaspy T.K. Wood E. Vatsa D. Abbott A.E. McGee S.C. Baxter L.C. Executive Function and Functional and Structural Brain Differences in Middle-Age Adults with Autism Spectrum Disorder Autism Res. 2017 10 1945 1959 10.1002/aur.1842 28940848

상세보기
36. Eilam-Stock T. Wu T. Spagna A. Egan L.J. Fan J. Neuroanatomical Alterations in High-Functioning Adults with Autism Spectrum Disorder Front. Neurosci. 2016 10 237 10.3389/fnins.2016.00237 27313505

상세보기
37. Turner A.H. Greenspan K.S. van Erp T.G.M. Pallidum and Lateral Ventricle Volume Enlargement in Autism Spectrum Disorder Psychiatry Res. Neuroimaging 2016 252 40 45 10.1016/j.pscychresns.2016.04.003 27179315

상세보기
38. Zhang W. Groen W. Mennes M. Greven C. Buitelaar J. Rommelse N. Revisiting Subcortical Brain Volume Correlates of Autism in the ABIDE Dataset: Effects of Age and Sex Psychol. Med. 2018 48 654 668 10.1017/S003329171700201X 28745267

상세보기
39. Mosconi M.W. Cody-Hazlett H. Poe M.D. Gerig G. Gimpel-Smith R. Piven J. Longitudinal Study of Amygdala Volume and Joint Attention in 2- to 4-Year-Old Children with Autism Arch. Gen. Psychiatry 2009 66 509 516 10.1001/archgenpsychiatry.2009.19 19414710

상세보기
40. Nacewicz B.M. Dalton K.M. Johnstone T. Long M.T. McAuliff E.M. Oakes T.R. Alexander A.L. Davidson R.J. Amygdala Volume and Nonverbal Social Impairment in Adolescent and Adult Males with Autism Arch. Gen. Psychiatry 2006 63 1417 1428 10.1001/archpsyc.63.12.1417 17146016

상세보기
41. Lopez-Larson M.P. King J.B. Terry J. McGlade E.C. Yurgelun-Todd D. Reduced Insular Volume in Attention Deficit Hyperactivity Disorder Psychiatry Res. Neuroimaging 2012 204 32 39 10.1016/j.pscychresns.2012.09.009

상세보기
42. Pagnozzi A.M. Conti E. Calderoni S. Fripp J. Rose S.E. A Systematic Review of Structural MRI Biomarkers in Autism Spectrum Disorder: A Machine Learning Perspective Int. J. Dev. Neurosci. 2018 71 68 82 10.1016/j.ijdevneu.2018.08.010 30172895

상세보기
43. Chang Y.-S. Owen J.P. Desai S.S. Hill S.S. Arnett A.B. Harris J. Marco E.J. Mukherjee P. Autism and Sensory Processing Disorders: Shared White Matter Disruption in Sensory Pathways But Divergent Connectivity in Social-Emotional Pathways PLoS ONE 2014 9 e103038 10.1371/journal.pone.0103038 25075609

상세보기
44. Dziuk M.A. Larson J.C.G. Apostu A. Mahone E.M. Denckla M.B. Mostofsky S.H. Dyspraxia in Autism: Association with Motor, Social and Communicative Deficits Dev. Med. Child Neurol. 2007 49 734 739 10.1111/j.1469-8749.2007.00734.x 17880641

상세보기
45. Mostofsky S.H. Burgess M.P. Gidley Larson J.C. Increased Motor Cortex White Matter Volume Predicts Motor Impairment in Autism Brain 2007 130 2117 2122 10.1093/brain/awm129 17575280

상세보기
46. Hanaie R. Mohri I. Kagitani-Shimono K. Tachibana M. Matsuzaki J. Hirata I. Nagatani F. Watanabe Y. Fujita N. Taniike M. White Matter Volume in the Brainstem and Inferior Parietal Lobule Is Related to Motor Performance in Children with Autism Spectrum Disorder: A Voxel-Based Morphometry Study Autism Res. 2016 9 981 992 10.1002/aur.1605 26808675

상세보기
47. Fuster J.M. Uyeda A.A. Reactivity of Limbic Neurons of the Monkey to Appetitive and Aversive Signals Electroencephalogr. Clin. Neurophysiol. 1971 30 281 293 10.1016/0013-4694(71)90111-8 4103500

상세보기
48. Adolphs R. Tranel D. Hamann S. Young A.W. Calder A.J. Phelps E.A. Anderson A. Lee G.P. Damasio A.R. Recognition of Facial Emotion in Nine Individuals with Bilateral Amygdala Damage Neuropsychologia 1999 37 1111 1117 10.1016/S0028-3932(99)00039-1 10509833

상세보기
49. Peck C.J. Salzman C.D. The Amygdala and Basal Forebrain as a Pathway for Motivationally Guided Attention J. Neurosci. 2014 34 13757 13767 10.1523/JNEUROSCI.2106-14.2014 25297102

상세보기
50. Pierce K. Haist F. Sedaghat F. Courchesne E. The Brain Response to Personally Familiar Faces in Autism: Findings of Fusiform Activity and Beyond Brain 2004 127 2703 2716 10.1093/brain/awh289 15319275

상세보기
51. Rudie J.D. Brown J.A. Beck-Pancer D. Hernandez L.M. Dennis E.L. Thompson P.M. Bookheimer S.Y. Dapretto M. Altered Functional and Structural Brain Network Organization in Autism NeuroImage Clin. 2012 2 79 94 10.1016/j.nicl.2012.11.006 24179761

상세보기
52. Iacoboni M. Dapretto M. The Mirror Neuron System and the Consequences of Its Dysfunction Nat. Rev. Neurosci. 2006 7 942 951 10.1038/nrn2024 17115076

상세보기
53. Tottenham N. Hertzig M.E. Gillespie-Lynch K. Gilhooly T. Millner A.J. Casey B.J. Elevated Amygdala Response to Faces and Gaze Aversion in Autism Spectrum Disorder Soc. Cogn. Affect. Neurosci. 2014 9 106 117 10.1093/scan/nst050 23596190

상세보기
54. Dalton K.M. Nacewicz B.M. Johnstone T. Schaefer H.S. Gernsbacher M.A. Goldsmith H.H. Alexander A.L. Davidson R.J. Gaze Fixation and The Neural Circuitry of Face Processing in Autism Nat. Neurosci. 2005 8 519 526 10.1038/nn1421 15750588

상세보기
55. Kleinhans N.M. Richards T. Weaver K. Johnson L.C. Greenson J. Dawson G. Aylward E. Association Between Amygdala Response to Emotional Faces and Social Anxiety in Autism Spectrum Disorders Neuropsychologia 2010 48 3665 3670 10.1016/j.neuropsychologia.2010.07.022 20655320

상세보기
56. Kylliäinen A. Wallace S. Coutanche M.N. Leppänen J.M. Cusack J. Bailey A.J. Hietanen J.K. Affective-Motivational Brain Responses to Direct Gaze in Children with Autism Spectrum Disorder J. Child Psychol. Psychiatry 2012 53 790 797 10.1111/j.1469-7610.2011.02522.x 22276654

상세보기
57. Pelphrey K.A. Morris J.P. McCarthy G. Neural Basis of Eye Gaze Processing Deficits in Autism Brain 2005 128 1038 1048 10.1093/brain/awh404 15758039

상세보기
58. Klin A. Jones W. Schultz R. Volkmar F. Cohen D. Visual Fixation Patterns during Viewing of Naturalistic Social Situations as Predictors of Social Competence in Individuals with Autism Arch. Gen. Psychiatry 2002 59 809 816 10.1001/archpsyc.59.9.809 12215080

상세보기
59. Moriuchi J.M. Klin A. Jones W. Mechanisms of Diminished Attention to Eyes in Autism Am. J. Psychiatry 2017 174 26 35 10.1176/appi.ajp.2016.15091222 27855484
60. Schieber M.H. Baker J.F. Control of Movement Fundamental Neuroscience Academic Press Cambridge, MA, USA 2013 631 651
61. Odriozola P. Uddin L.Q. Lynch C.J. Kochalka J. Chen T. Menon V. Insula Response and Connectivity During Social and Non-Social Attention in Children with Autism Soc. Cogn. Affect. Neurosci. 2016 11 433 444 10.1093/scan/nsv126 26454817

상세보기
62. Menon V. Uddin L.Q. Saliency, Switching, Attention and Control: A Network Model of Insula Function Brain Struct. Funct. 2010 214 655 667 10.1007/s00429-010-0262-0 20512370

상세보기
63. DuBois D. Ameis S.H. Lai M.-C. Casanova M.F. Desarkar P. Interoception in Autism Spectrum Disorder: A Review Int. J. Dev. Neurosci. 2016 52 104 111 10.1016/j.ijdevneu.2016.05.001 27269967

상세보기
64. Abbott A.E. Nair A. Keown C.L. Datko M. Jahedi A. Fishman I. Müller R.-A. Patterns of Atypical Functional Connectivity and Behavioral Links in Autism Differ Between Default, Salience and Executive Networks Cereb. Cortex 2016 26 4034 4045 10.1093/cercor/bhv191 26351318

상세보기
65. Delmonte S. Gallagher L. O’Hanlon E. McGrath J. Balsters J.H. Functional and Structural Connectivity of Frontostriatal Circuitry in Autism Spectrum Disorder Front. Hum. Neurosci. 2013 7 430 10.3389/fnhum.2013.00430 23964221

상세보기
66. Uddin L.Q. Menon V. The Anterior Insula in Autism: Under-Connected and Under-Examined Neurosci. Biobehav. Rev. 2009 33 1198 1203 10.1016/j.neubiorev.2009.06.002 19538989

상세보기
67. Haist F. Adamo M. Westerfield M. Courchesne E. Townsend J. The Functional Neuroanatomy of Spatial Attention in Autism Spectrum Disorder Dev. Neuropsychol. 2005 27 425 458 10.1207/s15326942dn2703_7 15843105

상세보기
68. Di Martino A. Ross K. Uddin L.Q. Sklar A.B. Castellanos F.X. Milham M.P. Functional Brain Correlates of Social and Nonsocial Processes in Autism Spectrum Disorders: An Activation Likelihood Estimation Meta-Analysis Biol. Psychiatry 2009 65 63 74 10.1016/j.biopsych.2008.09.022 18996505

상세보기
69. Shafritz K.M. Dichter G.S. Baranek G.T. Belger A. The Neural Circuitry Mediating Shifts in Behavioral Response and Cognitive Set in Autism Biol. Psychiatry 2008 63 974 980 10.1016/j.biopsych.2007.06.028 17916328

상세보기
70. Kana R.K. Keller T.A. Minshew N.J. Just M.A. Inhibitory Control in High-Functioning Autism: Decreased Activation and Underconnectivity in Inhibition Networks Biol. Psychiatry 2007 62 198 206 10.1016/j.biopsych.2006.08.004 17137558

상세보기
71. Schmitz N. Rubia K. Daly E. Smith A. Williams S. Murphy D.G.M. Neural Correlates of Executive Function in Autistic Spectrum Disorders Biol. Psychiatry 2006 59 7 16 10.1016/j.biopsych.2005.06.007 16140278

상세보기
72. Power J.D. Barnes K.A. Snyder A.Z. Schlaggar B.L. Petersen S.E. Spurious But Systematic Correlations in Functional Connectivity MRI Networks Arise From Subject Motion Neuroimage 2012 59 2142 2154 10.1016/j.neuroimage.2011.10.018 22019881

상세보기
73. Supekar K. Uddin L.Q. Khouzam A. Phillips J. Gaillard W.D. Kenworthy L.E. Yerys B.E. Vaidya C.J. Menon V. Brain Hyperconnectivity in Children with Autism and Its Links to Social Deficits Cell Rep. 2013 5 738 747 10.1016/j.celrep.2013.10.001 24210821

상세보기
74. Uddin L.Q. Supekar K. Menon V. Reconceptualizing Functional Brain Connectivity in Autism from a Developmental Perspective Front. Hum. Neurosci. 2013 7 458 10.3389/fnhum.2013.00458 23966925

상세보기
75. Rudie J.D. Shehzad Z. Hernandez L.M. Colich N.L. Bookheimer S.Y. Iacoboni M. Dapretto M. Reduced Functional Integration and Segregation of Distributed Neural Systems Underlying Social and Emotional Information Processing in Autism Spectrum Disorders Cereb. Cortex 2012 22 1025 1037 10.1093/cercor/bhr171 21784971

상세보기
76. Noonan S.K. Haist F. Müller R.-A. Aberrant Functional Connectivity in Autism: Evidence from Low-Frequency BOLD Signal Fluctuations Brain Res. 2009 1262 48 63 10.1016/j.brainres.2008.12.076 19401185

상세보기
77. Stevens W.D. Spreng R.N. Resting-State Functional Connectivity MRI Reveals Active Processes Central to Cognition Wiley Interdiscip. Rev. Cogn. Sci. 2014 5 233 245 10.1002/wcs.1275 26304310

상세보기
78. Zhang D. Raichle M.E. Disease and The Brain’s Dark Energy Nat. Rev. Neurol. 2010 6 15 28 10.1038/nrneurol.2009.198 20057496

상세보기
79. Maximo J.O. Kana R.K. Aberrant “Deep Connectivity” in Autism: A Cortico-Subcortical Functional Connectivity Magnetic Resonance Imaging Study Autism Res. 2019 10.1002/aur.2058 30624021

상세보기
80. Takarae Y. Luna B. Minshew N.J. Sweeney J.A. Visual Motion Processing and Visual Sensorimotor Control in Autism J. Int. Neuropsychol. Soc. 2014 20 113 122 10.1017/S1355617713001203 24365486

상세보기
81. Linke A.C. Jao Keehn R.J. Pueschel E.B. Fishman I. Müller R.-A. Children with ASD Show Links between Aberrant Sound Processing, Social Symptoms and Atypical Auditory Interhemispheric and Thalamocortical Functional Connectivity Dev. Cogn. Neurosci. 2018 29 117 126 10.1016/j.dcn.2017.01.007 28223033

상세보기
82. Cerliani L. Mennes M. Thomas R.M. Di Martino A. Thioux M. Keysers C. Increased Functional Connectivity Between Subcortical and Cortical Resting-State Networks in Autism Spectrum Disorder JAMA Psychiatry 2015 72 767 777 10.1001/jamapsychiatry.2015.0101 26061743

상세보기
83. Kaiser M.D. Yang D.Y.-J. Voos A.C. Bennett R.H. Gordon I. Pretzsch C. Beam D. Keifer C. Eilbott J. McGlone F. Brain Mechanisms for Processing Affective (And Nonaffective) Touch Are Atypical in Autism Cereb. Cortex 2016 26 2705 2714 10.1093/cercor/bhv125 26048952

상세보기
84. Keown C.L. Shih P. Nair A. Peterson N. Mulvey M.E. Müller R.-A. Local Functional Overconnectivity in Posterior Brain Regions Is Associated with Symptom Severity in Autism Spectrum Disorders Cell Rep. 2013 5 567 572 10.1016/j.celrep.2013.10.003 24210815

상세보기
85. Acevedo B. Aron E. Pospos S. Jessen D. The Functional Highly Sensitive Brain: A Review of the Brain Circuits Underlying Sensory Processing Sensitivity and Seemingly Related Disorders Philos. Trans. R. Soc. B Biol. Sci. 2018 373 20170161 10.1098/rstb.2017.0161

상세보기
86. Green S.A. Hernandez L.M. Bowman H.C. Bookheimer S.Y. Dapretto M. Sensory Over-Responsivity and Social Cognition in ASD: Effects of Aversive Sensory Stimuli and Attentional Modulation on Neural Responses to Social Cues Dev. Cogn. Neurosci. 2018 29 127 139 10.1016/j.dcn.2017.02.005 28284787

상세보기
87. Green S.A. Ben-Sasson A. Soto T.W. Carter A.S. Anxiety and Sensory Over-Responsivity in Toddlers with Autism Spectrum Disorders: Bidirectional Effects across Time J. Autism Dev. Disord. 2012 42 1112 1119 10.1007/s10803-011-1361-3 21935727

상세보기
88. Green S.A. Hernandez L. Bookheimer S.Y. Dapretto M. Salience Network Connectivity in Autism Is Related to Brain and Behavioral Markers of Sensory Overresponsivity J. Am. Acad. Child Adolesc. Psychiatry 2016 55 618 626 10.1016/j.jaac.2016.04.013 27343889

상세보기
89. Cascio C.J. Moana-Filho E.J. Guest S. Nebel M.B. Weisner J. Baranek G.T. Essick G.K. Perceptual and Neural Response to Affective Tactile Texture Stimulation in Adults with Autism Spectrum Disorders Autism Res. 2012 5 231 244 10.1002/aur.1224 22447729

상세보기
90. Le Couteur A. Lord C. Rutter M. Autism Diagnostic Interview–Revised (ADI-R) Western Psychological Services Los Angeles, CA, USA 2003
91. Green S.A. Hernandez L. Bookheimer S.Y. Dapretto M. Reduced Modulation of Thalamocortical Connectivity during Exposure to Sensory Stimuli in ASD Autism Res. 2017 10 801 809 10.1002/aur.1726 27896947

상세보기
92. Green S.A. Rudie J.D. Colich N.L. Wood J.J. Shirinyan D. Hernandez L. Tottenham N. Dapretto M. Bookheimer S.Y. Overreactive Brain Responses to Sensory Stimuli in Youth with Autism Spectrum Disorders J. Am. Acad. Child Adolesc. Psychiatry 2013 52 1158 1172 10.1016/j.jaac.2013.08.004 24157390

상세보기
93. Green S.A. Hernandez L.M. Tottenham N. Krasileva K. Bookheimer S.Y. Dapretto M. Neurobiology of Sensory Overresponsivity in Youth with Autism Spectrum Disorders JAMA Psychiatry 2015 72 778 786 10.1001/jamapsychiatry.2015.0737 26061819

상세보기
94. Schoen S.A. Miller L.J. Green K.E. Pilot Study of the Sensory over-Responsivity Scales: Assessment and Inventory Am. J. Occup. Ther. 2008 62 393 406 10.5014/ajot.62.4.393 18712002

상세보기
95. Wang A.T. Lee S.S. Sigman M. Dapretto M. Neural Basis of Irony Comprehension in Children with Autism: The Role of Prosody and Context Brain 2006 129 932 943 10.1093/brain/awl032 16481375

상세보기
96. Fang Z. Li H. Chen G. Yang J. Unconscious Processing of Negative Animals and Objects: Role of the Amygdala Revealed by FMRI Front. Hum. Neurosci. 2016 10 146 10.3389/fnhum.2016.00146 27092067

상세보기
97. Morris J.S. Öhman A. Dolan R.J. Conscious and Unconscious Emotional Learning in the Human Amygdala Nature 1998 393 467 470 10.1038/30976 9624001

상세보기
98. Schultz W. Reward Processing in Primate Orbitofrontal Cortex and Basal Ganglia Cereb. Cortex 2000 10 272 283 10.1093/cercor/10.3.272 10731222

상세보기
99. Caston J. Chianale C. Delhaye-Bouchaud N. Mariani J. Role of the Cerebellum in Exploration Behavior Brain Res. 1998 808 232 237 10.1016/S0006-8993(98)00847-6 9767169

상세보기
100. Chevallier C. Kohls G. Troiani V. Brodkin E.S. Schultz R.T. The Social Motivation Theory Trends Cogn. Sci. 2012 16 231 239 10.1016/j.tics.2012.02.007 22425667

상세보기
101. Scott-Van Zeeland A.A. Dapretto M. Ghahremani D.G. Poldrack R.A. Bookheimer S.Y. Reward Processing in Autism Autism Res. 2010 3 53 67 10.1002/aur.122 20437601

상세보기
102. Kuhl P.K. Coffey-Corina S. Padden D. Dawson G. Links between Social and Linguistic Processing of Speech in Preschool Children with Autism: Behavioral and Electrophysiological Measures Dev. Sci. 2005 8 F1 F12 10.1111/j.1467-7687.2004.00384.x 15647058

상세보기
103. Abrams D.A. Lynch C.J. Cheng K.M. Phillips J. Supekar K. Ryali S. Uddin L.Q. Menon V. Underconnectivity between Voice-Selective Cortex and Reward Circuitry in Children with Autism Proc. Natl. Acad. Sci. USA 2013 10.1073/pnas.1302982110 23776244

상세보기
104. Nomi J.S. Uddin L.Q. Face processing in autism spectrum disorders: From brain regions to brain networks Neuropsychologia 2015 71 201 216 10.1016/j.neuropsychologia.2015.03.029 25829246

상세보기
105. Williams E.H. Cross E.S. Decreased Reward Value of Biological Motion among Individuals with Autistic Traits Cognition 2018 171 1 9 10.1016/j.cognition.2017.10.017 29101779

상세보기
106. Delmonte S. Balsters J.H. McGrath J. Fitzgerald J. Brennan S. Fagan A.J. Gallagher L. Social and Monetary Reward Processing in Autism Spectrum Disorders Mol. Autism 2012 3 7 10.1186/2040-2392-3-7 23014171

상세보기
107. Kohls G. Schulte-Rüther M. Nehrkorn B. Müller K. Fink G.R. Kamp-Becker I. Herpertz-Dahlmann B. Schultz R.T. Konrad K. Reward System Dysfunction in Autism Spectrum Disorders Soc. Cogn. Affect. Neurosci. 2013 8 565 572 10.1093/scan/nss033 22419119

상세보기
108. Fletcher-Watson S. Leekam S.R. Benson V. Frank M.C. Findlay J.M. Eye-Movements Reveal Attention to Social Information in Autism Spectrum Disorder Neuropsychologia 2009 47 248 257 10.1016/j.neuropsychologia.2008.07.016 18706434

상세보기
109. Sepeta L. Tsuchiya N. Davies M.S. Sigman M. Bookheimer S.Y. Dapretto M. Abnormal Social Reward Processing in Autism as Indexed by Pupillary Responses to Happy Faces J. Neurodev. Disord. 2012 4 10.1186/1866-1955-4-17 22958650

상세보기
110. Martineau J. Aguillon-Hernandez N. Roche L. Malvy J. Mofid Y. Barthelemy C. Elian J.-C. Bonnet-Brilhault F. Interactions Sociales: Explorations Oculaires Et Pupillométrie Dans L’autisme De V Enfant [Social Interactions: Visual Exploration Behavior and Pupillary Reactivity in The Case of Children with Autism] ANAE Approche Neuropsychol. Apprentiss. l’Enfant 2016 28 333 338
111. Jones W. Carr K. Klin A. Absence of Preferential Looking to the Eyes of Approaching Adults Predicts Level of Social Disability in 2-Year-Old Toddlers with Autism Spectrum Disorder Arch. Gen. Psychiatry 2008 65 946 954 10.1001/archpsyc.65.8.946 18678799

상세보기
112. Sterling L. Dawson G. Webb S. Murias M. Munson J. Panagiotides H. Aylward E. The Role of Face Familiarity in Eye Tracking of Faces by Individuals with Autism Spectrum Disorders J. Autism Dev. Disord. 2008 38 1666 1675 10.1007/s10803-008-0550-1 18306030

상세보기
113. Pelphrey K.A. Sasson N.J. Reznick J.S. Paul G. Goldman B.D. Piven J. Visual Scanning of Faces in Autism J. Autism Dev. Disord. 2002 32 249 261 10.1023/A:1016374617369 12199131

상세보기
114. Critchley H.D. Daly E.M. Bullmore E.T. Williams S.C. Van Amelsvoort T. Robertson D.M. Rowe A. Phillips M. McAlonan G. Howlin P. The Functional Neuroanatomy of Social Behaviour: Changes in Cerebral Blood Flow When People with Autistic Disorder Process Facial Expressions Brain 2000 123 2203 2212 10.1093/brain/123.11.2203 11050021

상세보기
115. Dichter G.S. Felder J.N. Green S.R. Rittenberg A.M. Sasson N.J. Bodfish J.W. Reward Circuitry Function in Autism Spectrum Disorders Soc. Cogn. Affect. Neurosci. 2012 7 160 172 10.1093/scan/nsq095 21148176

상세보기
116. Assaf M. Hyatt C.J. Wong C.G. Johnson M.R. Schultz R.T. Hendler T. Pearlson G.D. Mentalizing and Motivation Neural Function during Social Interactions in Autism Spectrum Disorders NeuroImage Clin. 2013 3 321 331 10.1016/j.nicl.2013.09.005 24273716

상세보기
117. Pelphrey K.A. Michelich C.R. Viola R.J. Mack P.B. Allison T. Mccarthy G. Neurofunctional Organization of Biological Motion Perception: An FMRI Study of Eye, Hand and Mouth Movements Hand 2003 2 6
118. Klin A. Lin D.J. Gorrindo P. Ramsay G. Jones W. Two-Year-Olds with Autism Orient to Non-Social Contingencies Rather Than Biological Motion Nature 2009 459 257 261 10.1038/nature07868 19329996

상세보기
119. Ventola P. Yang D.Y.J. Friedman H.E. Oosting D. Wolf J. Sukhodolsky D.G. Pelphrey K.A. Heterogeneity of Neural Mechanisms of Response to Pivotal Response Treatment Brain Imaging Behav. 2015 9 74 88 10.1007/s11682-014-9331-y 25370452

상세보기
120. Yang J. Hofmann J. Action Observation and Imitation in Autism Spectrum Disorders: An ALE Meta-Analysis of FMRI Studies Brain Imaging Behav. 2016 10 960 969 10.1007/s11682-015-9456-7 26404019

상세보기
121. Nair G. Schmidt K. Febo M. Segarra A.C. Ferris C.F. Duong T.Q. The Neural Consequences of Repeated Cocaine Exposure Revealed by Functional MRI in Awake Rats Neuropsychopharmacology 2005 30 936 943 10.1038/sj.npp.1300653 15637636

상세보기
122. Richard J.M. Castro D.C. DiFeliceantonio A.G. Robinson M.J.F. Berridge K.C. Mapping Brain Circuits of Reward and Motivation: in The Footsteps of Ann Kelley Neurosci. Biobehav. Rev. 2013 37 1919 1931 10.1016/j.neubiorev.2012.12.008 23261404

상세보기
123. Wittmann M. Lovero K.L. Lane S.D. Paulus M.P. Now or Later? Striatum and Insula Activation to Immediate Versus Delayed Rewards J. Neurosci. Psychol. Econ. 2010 3 15 26 10.1037/a0017252 20657814

상세보기
124. Clements C.C. Zoltowski A.R. Yankowitz L.D. Yerys B.E. Schultz R.T. Herrington J.D. Evaluation of The Social Motivation Hypothesis of Autism JAMA Psychiatry 2018 75 797 808 10.1001/jamapsychiatry.2018.1100 29898209

상세보기
125. O’Doherty J.P. Deichmann R. Critchley H.D. Dolan R.J. Neural Responses during Anticipation of a Primary Taste Reward Neuron 2002 33 815 826 10.1016/S0896-6273(02)00603-7 11879657

상세보기
126. O’Doherty J. Rolls E.T. Francis S. Bowtell R. McGlone F. Representation of Pleasant and Aversive Taste in the Human Brain J. Neurophysiol. 2001 85 1315 1321 10.1152/jn.2001.85.3.1315 11248000

상세보기
127. Thut G. Schultz W. Roelcke U. Nienhusmeier M. Missimer J. Maguire R.P. Leenders K.L. Activation of the Human Brain by Monetary Reward Neuroreport 1997 8 1225 1228 10.1097/00001756-199703240-00033 9175118

상세보기
128. Phillips M.L. Bullmore E.T. Howard R. Woodruff P.W. Wright I.C. Williams S.C. Simmons A. Andrew C. Brammer M. David A.S. Investigation of Facial Recognition Memory and Happy and Sad Facial Expression Perception: An FMRI Study Psychiatry Res. Neuroimaging 1998 83 127 138 10.1016/S0925-4927(98)00036-5

상세보기
129. Haber S.N. Knutson B. The Reward Circuit: Linking Primate Anatomy and Human Imaging Neuropsychopharmacology 2010 35 4 26 10.1038/npp.2009.129 19812543

상세보기
130. O’Connell L.A. Hofmann H.A. The Vertebrate Mesolimbic Reward System and Social Behavior Network: A Comparative Synthesis J. Comp. Neurol. 2011 519 3599 3639 10.1002/cne.22735 21800319

상세보기
131. Berridge K.C. Kringelbach M.L. Pleasure Systems in the Brain Neuron 2015 86 646 664 10.1016/j.neuron.2015.02.018 25950633

상세보기
132. Supekar K. Kochalka J. Schaer M. Wakeman H. Qin S. Padmanabhan A. Menon V. Deficits in Mesolimbic Reward Pathway Underlie Social Interaction Impairments in Children with Autism Brain 2018 141 2795 2805 10.1093/brain/awy191 30016410
133. Pierce K. Courchesne E. Evidence for a Cerebellar Role in Reduced Exploration and Stereotyped Behavior in Autism Biol. Psychiatry 2001 49 655 664 10.1016/S0006-3223(00)01008-8 11313033

상세보기
134. Schmahmann J.D. Disorders of the Cerebellum: Ataxia, Dysmetria of Thought and the Cerebellar Cognitive Affective Syndrome J. Neuropsychiatry Clin. Neurosci. 2004 16 367 378 10.1176/jnp.16.3.367 15377747

상세보기
135. Schutter D.J.L.G. Human Cerebellum in Motivation and Emotion Handbook of the Cerebellum and Cerebellar Disorders Springer Dordrecht, The Netherlands 2013 1771 1782
136. Wise R.A. Roles for Nigrostriatal-Not Just Mesocorticolimbic-Dopamine in Reward and Addiction Trends Neurosci. 2009 10.1016/j.tins.2009.06.004

상세보기
137. Schmahmann J.D. The Role of the Cerebellum in Affect and Psychosis J. Neurolinguist. 2000 13 189 214 10.1016/S0911-6044(00)00011-7

상세보기
138. Ebner T.J. Pasalar S. Cerebellum Predicts the Future Motor State Cerebellum 2008 7 583 588 10.1007/s12311-008-0059-3 18850258

상세보기
139. Courchesne E. Brainstem, Cerebellar and Limbic Neuroanatomical Abnormalities in Autism Curr. Opin. Neurobiol. 1997 7 269 278 10.1016/S0959-4388(97)80016-5 9142760

상세보기
140. Stanfield A.C. McIntosh A.M. Spencer M.D. Philip R. Gaur S. Lawrie S.M. Towards a Neuroanatomy of Autism: A Systematic Review and Meta-Analysis of Structural Magnetic Resonance Imaging Studies Eur. Psychiatry 2008 23 289 299 10.1016/j.eurpsy.2007.05.006 17765485

상세보기
141. Keown C.L. Datko M.C. Chen C.P. Maximo J.O. Jahedi A. Müller R.-A. Network Organization Is Globally Atypical in Autism: A Graph Theory Study of Intrinsic Functional Connectivity Biol. Psychiatry Cogn. Neurosci. Neuroimaging 2017 2 66 75 10.1016/j.bpsc.2016.07.008 28944305

상세보기
142. Ornitz E.M. Vestibular Dysfunction in Schizophrenia and Childhood Autism Compr. Psychiatry 1970 11 159 173 10.1016/0010-440X(70)90157-4 4314258

상세보기
143. Ritvo E.R. Ornitz E.M. Eviatar A. Markham C.H. Brown M.B. Mason A. Decreased Postrotatory Nystagmus in Early Infantile Autism Neurology 1969 19 653 658 10.1212/WNL.19.7.653 5815129

상세보기
144. Maurer R.G. Damasio A.R. Vestibular Dysfunction in Autistic Children Dev. Med. Child Neurol. 1979 21 656 659 10.1111/j.1469-8749.1979.tb01682.x 389718

상세보기
145. Ornitz E.M. Brown M.B. Mason A. Putnam N.H. Effect of Visual Input on Vestibular Nystagmus in Autistic Children Arch. Gen. Psychiatry 1974 10.1001/archpsyc.1974.01760150075011
146. Egawa J. Watanabe Y. Kitamura H. Endo T. Tamura R. Hasegawa N. Someya T. Reduced Thalamus Volume in Non-Right-Handed Male Patients with Autism Spectrum Disorders Psychiatry Clin. Neurosci. 2011 65 395 10.1111/j.1440-1819.2011.02210.x

상세보기
147. McAlonan G.M. Suckling J. Wong N. Cheung V. Lienenkaemper N. Cheung C. Chua S.E. Distinct Patterns of Grey Matter Abnormality in High-Functioning Autism and Asperger’s Syndrome J. Child Psychol. Psychiatry 2008 49 1287 1295 10.1111/j.1469-7610.2008.01933.x 18673405

상세보기
148. Spencer J.V. O’Brien J.M.D. Visual Form-Processing Deficits in Autism Perception 2006 35 1047 1055 10.1068/p5328 17076065

상세보기
149. Waiter G.D. Williams J.H. Murray A.D. Gilchrist A. Perrett D.I. Whiten A. A Voxel-Based Investigation of Brain Structure in Male Adolescents with Autistic Spectrum Disorder Neuroimage 2004 22 619 625 10.1016/j.neuroimage.2004.02.029 15193590

상세보기
150. Carson T.B. Wilkes B.J. Patel K. Pineda J.L. Ko J.H. Newell K.M. Bodfish J.W. Schubert M.C. Radonovich K. White K.D. Vestibulo-Ocular Reflex Function in Children with High-Functioning Autism Spectrum Disorders Autism Res. 2017 10 251 266 10.1002/aur.1642 27220548

상세보기
151. Goldberg M.C. Landa R. Lasker A. Cooper L. Zee D.S. Evidence of Normal Cerebellar Control of the Vestibulo-Ocular Reflex (VOR) in Children with High-Functioning Autism J. Autism Dev. Disord. 2000 30 519 524 10.1023/A:1005631225367 11261464

상세보기
152. Widiger T.A. Diagnostic and Statistical Manual of Mental Disorders Encyclopedia of Psychology American Psychological Association Washington, DC, USA 2000 Volume 3 32 35
153. Ben-Sasson A. Hen L. Fluss R. Cermak S.A. Engel-Yeger B. Gal E. A Meta-Analysis of Sensory Modulation Symptoms in Individuals with Autism Spectrum Disorders J. Autism Dev. Disord. 2009 39 1 11 10.1007/s10803-008-0593-3 18512135

상세보기
154. Salimpoor V.N. van den Bosch I. Kovacevic N. McIntosh A.R. Dagher A. Zatorre R.J. Interactions Between the Nucleus Accumbens and Auditory Cortices Predict Music Reward Value Science 2013 340 216 219 10.1126/science.1231059 23580531

상세보기
155. Gordon I. Jack A. Pretzsch C.M. Vander Wyk B. Leckman J.F. Feldman R. Pelphrey K.A. Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism Sci. Rep. 2016 6 35054 10.1038/srep35054 27845765

상세보기
156. Toback M. Zangeneh K. Siddiqui T.J. Marzban H. Neurodevelopmental Disorders of the Cerebellum: Autism Spectrum Disorder Development of the Cerebellum from Molecular Aspects to Diseases Springer Cham, Switzerland 2017 369 387

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