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NTIS 바로가기Molecular cancer research, v.18 no.1, 2020년, pp.118 - 129
Lee, Soobeom (Laboratory for Systems Biology and Bio-inspired Engineering, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.) , Lee, Chansu (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.) , Hwang, Chae Young (Laboratory for Systems Biology and Bio-inspired Engineering, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.) , Kim, Dongsan (Laboratory for Systems Biology and Bio-inspired Engineering, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.) , Han, Younghyun (Laboratory for Systems Biology and Bio-inspired Engineering, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.) , Hong, Sung Noh (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of K) , Kim, Seok-Hyung , Cho, Kwang-Hyun
Cancer cells exhibit properties of cells in a less differentiated state than the adjacent normal cells in the tissue. We explored whether cancer cells can be converted to a differentiated normal-like state by restoring the gene regulatory network (GRN) of normal cells. Here, we report that colorecta...
Cell Bradner 168 629 2017 10.1016/j.cell.2016.12.013 Transcriptional addiction in cancer
Nat Genet Ben-Porath 40 499 2008 10.1038/ng.127 An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
Cell Stem Cell Wong 2 333 2008 10.1016/j.stem.2008.02.009 Module map of stem cell genes guides creation of epithelial cancer stem cells
Cell Suva 157 580 2014 10.1016/j.cell.2014.02.030 Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
Science Kaufman 351 aad2197 2016 10.1126/science.aad2197 A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
Science Suva 339 1567 2013 10.1126/science.1230184 Epigenetic reprogramming in cancer
Science Flavahan 357 eaal2380 2017 10.1126/science.aal2380 Epigenetic plasticity and the hallmarks of cancer
Nat Rev Cancer Califano 17 116 2017 10.1038/nrc.2016.124 The recurrent architecture of tumour initiation, progression and drug sensitivity
Cell Schwitalla 152 25 2013 10.1016/j.cell.2012.12.012 Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
Nature Shimokawa 545 187 2017 10.1038/nature22081 Visualization and targeting of LGR5(+) human colon cancer stem cells
Nat Genet Basso 37 382 2005 10.1038/ng1532 Reverse engineering of regulatory networks in human B cells
Cell Cahan 158 903 2014 10.1016/j.cell.2014.07.020 CellNet: network biology applied to stem cell engineering
Nat Genet Rackham 48 331 2016 10.1038/ng.3487 A predictive computational framework for direct reprogramming between human cell types
PLoS One Hrvatin 9 e89459 2014 10.1371/journal.pone.0089459 MARIS: method for analyzing RNA following intracellular sorting
Nat Commun Yeo 9 3016 2018 10.1038/s41467-018-05274-6 A positive feedback loop bi-stably activates fibroblasts
BMC Bioinformatics Hanzelmann 14 7 2013 10.1186/1471-2105-14-7 GSVA: gene set variation analysis for microarray and RNA-seq data
Nucleic Acids Res Ritchie 43 e47 2015 10.1093/nar/gkv007 limma powers differential expression analyses for RNA-sequencing and microarray studies
Proc Natl Acad Sci U S A Tusher 98 5116 2001 10.1073/pnas.091062498 Significance analysis of microarrays applied to the ionizing radiation response
BMC Bioinformatics Schwender 9 144 2008 10.1186/1471-2105-9-144 Empirical Bayes analysis of single nucleotide polymorphisms
Sci Signal Gao 6 pl1 2013 10.1126/scisignal.2004088 Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
Genome Biol Gentleman 5 R80 2004 10.1186/gb-2004-5-10-r80 Bioconductor: open software development for computational biology and bioinformatics
Genome Biol Welch 17 106 2016 10.1186/s13059-016-0975-3 SLICER: inferring branched, nonlinear cellular trajectories from single cell RNA-seq data
Nat Methods Qiu 14 979 2017 10.1038/nmeth.4402 Reversed graph embedding resolves complex single-cell trajectories
Nature Tirosh 539 309 2016 10.1038/nature20123 Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
Cell Stem Cell Grun 19 266 2016 10.1016/j.stem.2016.05.010 De novo prediction of stem cell identity using single-cell transcriptome data
Cell van Dijk 174 716 2018 10.1016/j.cell.2018.05.061 Recovering gene interactions from single-cell data using data diffusion
Nat Commun Fletcher 4 2464 2013 10.1038/ncomms3464 Master regulators of FGFR2 signalling and breast cancer risk
Nature Carro 463 318 2010 10.1038/nature08712 The transcriptional network for mesenchymal transformation of brain tumours
Nature FANTOM Consortium and the RIKEN PMI and CLST (DGT) 507 462 2014 10.1038/nature13182 A promoter-level mammalian expression atlas
Nat Genet Alvarez 48 838 2016 10.1038/ng.3593 Functional characterization of somatic mutations in cancer using network-based inference of protein activity
Nat Biotechnol Wang 27 829 2009 10.1038/nbt.1563 Genome-wide identification of post-translational modulators of transcription factor activity in human B cells
Bioinformatics Gautier 20 307 2004 10.1093/bioinformatics/btg405 affy-analysis of Affymetrix GeneChip data at the probe level
Nat Methods Langmead 9 357 2012 10.1038/nmeth.1923 Fast gapped-read alignment with Bowtie 2
Bioinformatics Quinlan 26 841 2010 10.1093/bioinformatics/btq033 BEDTools: a flexible suite of utilities for comparing genomic features
Bioinformatics Robinson 26 139 2010 10.1093/bioinformatics/btp616 edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Bioinformatics McCarthy 33 1179 2017 10.1093/bioinformatics/btw777 Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R
J Natl Cancer Inst O'Connell 96 1420 2004 10.1093/jnci/djh275 Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging
Nat Genet Li 49 708 2017 10.1038/ng.3818 Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors
EMBO J Munoz 31 3079 2012 10.1038/emboj.2012.166 The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers
Nature Barker 457 608 2009 10.1038/nature07602 Crypt stem cells as the cells-of-origin of intestinal cancer
Clin Cancer Res Du 14 6751 2008 10.1158/1078-0432.CCR-08-1034 CD44 is of functional importance for colorectal cancer stem cells
Cell Takahashi 126 663 2006 10.1016/j.cell.2006.07.024 Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
J Cancer Chen 8 3318 2017 10.7150/jca.20482 Histone methyltransferase SETDB1 promotes the progression of colorectal cancer by inhibiting the expression of TP53
Carcinogenesis Wei 27 23 2006 10.1093/carcin/bgi243 Emerging role of KLF4 in human gastrointestinal cancer
Cell Stem Cell Munera 21 51 2017 10.1016/j.stem.2017.05.020 Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling
Proc Natl Acad Sci U S A Liu 115 E5066 2018 PRDM1 silences stem cell-related genes and inhibits proliferation of human colon tumor organoids
Curr Opin Cell Biol Fodde 19 150 2007 10.1016/j.ceb.2007.02.007 Wnt/beta-catenin signaling in cancer stemness and malignant behavior
Cell Malta 173 338 2018 10.1016/j.cell.2018.03.034 Machine learning identifies stemness features associated with oncogenic dedifferentiation
Cell Dow 161 1539 2015 10.1016/j.cell.2015.05.033 Apc restoration promotes cellular differentiation and reestablishes crypt homeostasis in colorectal cancer
Curr Opin Syst Biol Cho 2 49 2017 10.1016/j.coisb.2017.01.005 Cancer reversion, a renewed challenge in systems biology
Wiley Interdiscip Rev Syst Biol Med Cho 8 366 2016 10.1002/wsbm.1346 The reverse control of irreversible biological processes
Nat Rev Cancer de Thé 18 117 2018 10.1038/nrc.2017.103 Differentiation therapy revisited
Oncotarget Cruz 3 559 2012 10.18632/oncotarget.512 Solid tumor differentiation therapy - is it possible?
Genes Dev Bilodeau 23 2484 2009 10.1101/gad.1837309 SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
Nature Ceol 471 513 2011 10.1038/nature09806 The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
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