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[해외논문] Blood component ridable and CD44 receptor targetable nanoparticles based on a maleimide-functionalized chondroitin sulfate derivative

Carbohydrate polymers, v.230, 2020년, pp.115568 -   

Lee, Jae-Young (College of Pharmacy, Chungnam National University) ,  Lee, Han Sol (College of Pharmacy, Chungnam National University) ,  Kang, Nae-Won (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ,  Lee, Song Yi (College of Pharmacy, Kangwon National University) ,  Kim, Dong Hyun (College of Pharmacy, Chungnam National University) ,  Kim, Sungyun (College of Pharmacy, Kangwon National University) ,  Yoon, In-Soo (Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University) ,  Cho, Hyun-Jong (College of Pharmacy, Kangwon National University) ,  Kim, Dae-Duk (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University)

Abstract AI-Helper 아이콘AI-Helper

Abstract Chondroitin sulfate A-deoxycholic acid-polyethylene glycol-maleimide (CSA-DOCA-PEG-MAL; CDPM) nanostructures were designed for the transient binding of MAL with thiol in blood components and cell membranes, in addition to the CD44 receptor targeting, for the therapy of breast cancer. The s...

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