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Ecancermedicalscience, v.2, 2008년, pp.114 -
Regenbrecht, C (Max Planck Institute for Molecular Genetics, Berlin, Germany) , Welte, Y (Clinical Research Group on Tumour Immunology, Department of Dermatology, Charite-Universitatsmedizin, Berlin, Germany) , Hugel, R (Clinical Research Group on Tumour Immunology, Department of Dermatology, Charite-Universitatsmedizin, Berlin, Germany) , Trefzer, U (Clinical Research Group on Tumour Immunology, Department of Dermatology, Charite-Universitatsmedizin, Berlin, Germany) , Losch, FO (Clinical Research Group on Tumour Immunology, Department of Dermatology, Charite-Universitatsmedizin, Berlin, Germany) , Adjaye, J (Max Planck Institute for Molecular Genetics, Berlin, Germany) , Walden, P (Clinical Research Group on Tumour Immunology, Department of Dermatology, Charite-Universitatsmedizin, Berlin, Germany)
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The identification of cancer stem cells in various malignancies led to the hypothesis that these cells have the exclusive ability of self-renewal, contribute to the plasticity of the tumours and may be the cause for ineffective cancer therapies. Several markers of melanoma stem cells have been descr...
1. Mihic-Probst D Kuster A Kilgus S Bode-Lesniewska B Ingold-Heppner B Leung C 2007 Consistent expression of the stem cell renewal factor BMI-1 in primary and metastatic melanoma Int J Cancer 121 8 1764 70 17597110 10.1002/ijc.22891 17597110
2. Klein WM Wu BP Zhao S Wu H Klein-Szanto AJ Tahan SR 2007 Increased expression of stem cell markers in malignant melanoma Mod Pathol 20 1 102 7 17143262 10.1038/modpathol.3800720 17143262
3. Goodell MA Brose K Paradis G Conner AS Mulligan RC 1996 Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo J Exp Med 183 4 1797 806 8666936 10.1084/jem.183.4.1797 8666936
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