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NTIS 바로가기International journal of immunopathology and pharmacology, v.30 no.3, 2017년, pp.238 - 252
Soundara Rajan, Thangavelu (IRCCS Centro Neurolesi “Bonino Pulejo,” Messina, Italy) , Giacoppo, Sabrina (IRCCS Centro Neurolesi “Bonino Pulejo,” Messina, Italy) , Diomede, Francesca (Stem Cells and Regenerative Medicine Laboratory, Department of Medical, Oral and Biotechnological Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy) , Bramanti, Placido (IRCCS Centro Neurolesi “Bonino Pulejo,” Messina, Italy) , Trubiani, Oriana (Stem Cells and Regenerative Medicine Laboratory, Department of Medical, Oral and Biotechnological Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy) , Mazzon, Emanuela (IRCCS Centro Neurolesi “Bonino Pulejo,” Messina, Italy)
Research in recent years has largely explored the immunomodulatory effects of mesenchymal stem cells (MSCs) and their secretory products, called “secretome,” in the treatment of neuroinflammatory diseases. Here, we examined whether such immunosuppressive effects might be elicited due to inflammasome...
1 Calabresi PA ( 2002 ) Considerations in the treatment of relapsing-remitting multiple sclerosis . Neurology 58 : S10 – S22 .
2 Frohman EM Racke MK Raine CS ( 2006 ) Multiple sclerosis–The plaque and its pathogenesis . The New England Journal of Medicine 354 : 942 – 955 . 16510748
3 Rieckmann P Smith KJ ( 2001 ) Multiple sclerosis: More than inflammation and demyelination . Trends Neuroscience 24 : 435 – 437 .
4 Ebers GC ( 2008 ) Environmental factors and multiple sclerosis . The Lancet Neurology 7 : 268 – 277 . 18275928
5 Compston A Coles A ( 2002 ) Multiple sclerosis . Lancet 359 : 1221 – 1231 . 11955556
6 Lublin FD Reingold SC Cohen JA et al ( 2014 ) Defining the clinical course of multiple sclerosis: The 2013 revisions . Neurology 83 : 278 – 286 . 24871874
7 Jancic J Nikolic B Ivancevic N et al ( 2016 ) Multiple sclerosis in pediatrics: Current concepts and treatment options . Neurology and Therapy 5 : 131 – 143 . 27640189
8 Dulamea A ( 2015 ) Mesenchymal stem cells in multiple sclerosis: Translation to clinical trials . Journal of Medicine and Life 8 : 24 – 27 .
9 Sarugaser R Hanoun L Keating A et al ( 2009 ) Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy . PLoS ONE 4 : e6498 . 19652709
10 Ullah I Subbarao RB Rho GJ ( 2015 ) Human mesenchymal stem cells: Current trends and future prospective . Bioscience reports 35 : e00191 . 25797907
11 Sharpe PT ( 2016 ) Dental mesenchymal stem cells . Development 143 : 2273 – 2280 . 27381225
12 Trubiani O Giacoppo S Ballerini P et al ( 2016 ) Alternative source of stem cells derived from human periodontal ligament: A new treatment for experimental autoimmune encephalomyelitis . Stem Cell Research & Therapy 7 : 1 . 26729060
13 Tatullo M Marrelli M Shakesheff KM et al ( 2015 ) Dental pulp stem cells: Function, isolation and applications in regenerative medicine . Journal of Tissue Engineering and Regenerative Medicine 9 : 1205 – 1216 . 24850632
14 Pashoutan Sarvar D Shamsasenjan K Akbarzadehlaleh P ( 2016 ) Mesenchymal stem cell-derived exosomes: New opportunity in cell-free therapy . Advanced Pharmaceutical Bulletin 6 : 293 – 299 . 27766213
15 Merino-Gonzalez C Zuniga FA Escudero C et al ( 2016 ) Mesenchymal stem cell-derived extracellular vesicles promote angiogenesis: Potencial clinical application . Frontiers in Physiology 7 : 24 . 26903875
16 Biancone L Bruno S Deregibus MC et al ( 2012 ) Therapeutic potential of mesenchymal stem cell-derived microvesicles . Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association–European Renal Association 27 : 3037 – 3042 .
17 Salgado AJ Sousa JC Costa BM et al ( 2015 ) Mesenchymal stem cells secretome as a modulator of the neurogenic niche: Basic insights and therapeutic opportunities . Frontiers in Cellular Neuroscience 9 : 249 . 26217178
18 Jarmalaviciute A Pivoriunas A ( 2016 ) Exosomes as a potential novel therapeutic tools against neurodegenerative diseases . Pharmacological Research 113 : 816 – 822 . 26855317
19 Rajan TS Giacoppo S Diomede F et al ( 2016 ) The secretome of periodontal ligament stem cells from MS patients protects against EAE . Scientific Reports 6 : 38743 . 27924938
20 Patel MN Carroll RG Galvan-Pena S et al ( 2017 ) Inflammasome priming in sterile inflammatory disease . Trends in Molecular Medicine 23 : 165 – 180 . 28109721
21 Guo H Callaway JB Ting JPY ( 2015 ) Inflammasomes: Mechanism of action, role in disease, and therapeutics . Nature Medicine 21 : 677 – 687 .
22 Shao B-Z Xu Z-Q Han B-Z et al ( 2015 ) NLRP3 inflammasome and its inhibitors: A review . Frontiers in Pharmacology 6 : 262 . 26594174
23 Eleuterio E Trubiani O Sulpizio M et al ( 2013 ) Proteome of human stem cells from periodontal ligament and dental pulp . PLoS ONE 8 : e71101 . 23940696
24 Paschalidis N Iqbal AJ Maione F et al ( 2009 ) Modulation of experimental autoimmune encephalomyelitis by endogenous annexin A1 . Journal of Neuroinflammation 6 : 33 . 19912648
25 Campbell AM Zagon IS McLaughlin PJ ( 2012 ) Opioid growth factor arrests the progression of clinical disease and spinal cord pathology in established experimental autoimmune encephalomyelitis . Brain Research 1472 : 138 – 148 . 22820301
26 Fleming KK Bovaird JA Mosier MC et al ( 2005 ) Statistical analysis of data from studies on experimental autoimmune encephalomyelitis . Journal of Neuroimmunology 170 : 71 – 84 . 16198426
27 Uccelli A Laroni A Freedman MS ( 2011 ) Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases . The Lancet Neurology 10 : 649 – 656 . 21683930
28 Paul G Anisimov SV ( 2013 ) The secretome of mesenchymal stem cells: Potential implications for neuroregeneration . Biochimie 95 : 2246 – 2256 . 23871834
29 Liu J Yu F Sun Y et al ( 2015 ) Concise reviews: Characteristics and potential applications of human dental tissue-derived mesenchymal stem cells . Stem Cells 33 : 627 – 638 . 25447379
30 Barclay W Shinohara ML ( 2016 ) Inflammasome activation in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE) . Brain Pathology 27 : 213 – 219 .
31 Gris D Ye Z Iocca HA et al ( 2010 ) NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses . Journal of Immunology 185 : 974 – 981 .
32 Inoue M Williams KL Gunn MD et al ( 2012 ) NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis . Proceedings of the National Academy of Sciences of the United States of America 109 : 10480 – 10485 . 22699511
33 Coclet-Ninin J Dayer JM Burger D ( 1997 ) Interferon-beta not only inhibits interleukin-1 beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells . European Cytokine Network 8 : 345 – 349 . 9459613
34 Nicoletti F Patti F DiMarco R et al ( 1996 ) Circulating serum levels of IL-1ra in patients with relapsing remitting multiple sclerosis are normal during remission phases but significantly increased either during exacerbations or in response to IFN-beta treatment . Cytokine 8 : 395 – 400 . 8726668
35 Dujmovic I Mangano K Pekmezovic T et al ( 2009 ) The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapy . Journal of Neuroimmunology 207 : 101 – 106 . 19162335
36 Cassel SL Sutterwala FS ( 2010 ) Sterile inflammatory responses mediated by the NLRP3 inflammasome . European Journal of Immunology 40 : 607 – 611 . 20201012
37 Kerfoot SM Long EM Hickey MJ et al ( 2004 ) TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease . Journal of Immunology 173 : 7070 – 7077 .
38 Reynolds JM Martinez GJ Chung Y et al ( 2012 ) Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation . Proceedings of the National Academy of Sciences of the United States of America 109 : 13064 – 13069 . 22826216
39 Pahan K Schmid M ( 2000 ) Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis . Neuroscience Letters 287 : 17 – 20 . 10841980
40 van Loo G De Lorenzi R Schmidt H et al ( 2006 ) Inhibition of transcription factor NF-kappaB in the central nervous system ameliorates autoimmune encephalomyelitis in mice . Nature Immunology 7 : 954 – 961 . 16892069
41 Zhang X Koldzic DN Izikson L et al ( 2004 ) IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells . International Immunology 16 : 249 – 256 . 14734610
42 Klose J Schmidt NO Melms A et al ( 2013 ) Suppression of experimental autoimmune encephalomyelitis by interleukin-10 transduced neural stem/progenitor cells . Journal of Neuroinflammation 10 : 117 . 24053338
43 Zhang X Reddy J Ochi H et al ( 2006 ) Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells . International Immunology 18 : 495 – 503 . 16540527
44 Laouar Y Town T Jeng D et al ( 2008 ) TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis . Proceedings of the National Academy of Sciences of the United States of America 105 : 10865 – 10870 . 18669656
45 Nicoletti F Di Marco R Patti F et al ( 1998 ) Blood levels of transforming growth factor-beta 1 (TGF-beta1) are elevated in both relapsing remitting and chronic progressive multiple sclerosis (MS) patients and are further augmented by treatment with interferon-beta 1b (IFN-beta1b) . Clinical & Experimental Immunology 113 : 96 – 99 . 9697990
46 Kvarnstrom M Ydrefors J Ekerfelt C et al ( 2013 ) Longitudinal interferon-beta effects in multiple sclerosis: Differential regulation of IL-10 and IL-17A, while no sustained effects on IFN-gamma, IL-4 or IL-13 . Journal of the Neurological Sciences 325 : 79 – 85 . 23273903
47 Gurung P Li B Subbarao Malireddi RK et al ( 2015 ) Chronic TLR stimulation controls NLRP3 inflammasome activation through IL-10 mediated regulation of NLRP3 expression and caspase-8 activation . Scientific Reports 5 : 14488 . 26412089
48 Stonier SW Schluns KS ( 2010 ) Trans-presentation: A novel mechanism regulating IL-15 delivery and responses . Immunology Letters 127 : 85 – 92 . 19818367
49 Yu P Bamford RN Waldmann TA ( 2014 ) IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells . European Journal of Immunology 44 : 3330 – 3341 . 25142300
50 Pandiyan P Yang X-P Saravanamuthu SS et al ( 2012 ) The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes . Journal of Immunology 189 : 4237 – 4246 .
51 Nanki T Lipsky PE ( 2000 ) Cutting edge: Stromal cell-derived factor-1 is a costimulator for CD4+ T cell activation . Journal of Immunology 164 : 5010 – 5014 .
52 Cui L Qu H Xiao T et al ( 2013 ) Stromal cell-derived factor-1 and its receptor CXCR4 in adult neurogenesis after cerebral ischemia . Restorative Neurology and Neuroscience 31 : 239 – 251 . 23482064
53 Meiron M Zohar Y Anunu R et al ( 2008 ) CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells . Journal of Experimental Medicine 205 : 2643 – 2655 . 18852294
54 Zendedel A Johann S Mehrabi S et al ( 2016 ) Activation and regulation of NLRP3 inflammasome by intrathecal application of SDF-1a in a spinal cord injury model . Molecular Neurobiology 53 : 3063 – 3075 . 25972240
55 Karpus WJ Kennedy KJ ( 1997 ) MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation . Journal of Leukocyte Biology 62 : 681 – 687 . 9365124
56 Tang SK Knobloch RA Maucksch C et al ( 2014 ) Redirection of doublecortin-positive cell migration by over-expression of the chemokines MCP-1, MIP-1alpha and GRO-alpha in the adult rat brain . Neuroscience 260 : 240 – 248 . 24361178
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