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Effects of Helminth Eradication on the Immune System 원문보기

Pathogens & immunity, v.2 no.2, 2017년, pp.293 - 307  

Weisman, Ziva (Kaplan Medical Center, Ben-Ari Institute of Clinical Immunology and AIDS Center, Rehovot, Israel) ,  Kalinkovich, Alexander (Hebrew University Hadassah Medical School, Jerusalem, Israel) ,  Stein, Miguel (Hebrew University Hadassah Medical School, Jerusalem, Israel) ,  Greenberg, Zalman (Hebrew University Hadassah Medical School, Jerusalem, Israel) ,  Borkow, Gad (Kaplan Medical Center, Ben-Ari Institute of Clinical Immunology and AIDS Center, Rehovot, Israel) ,  Adlerstein, David (Kaplan Medical Center, Ben-Ari Institute of Clinical Immunology and AIDS Center, Rehovot, Israel) ,  Mahdi, Jemal Ali (Department of Microbiology, Immunology and Parasitology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia) ,  Bentwich, Zvi (Kaplan Medical Center, Ben-Ari Institute of Clinical Immunology and AIDS Center, Rehovot, Israel)

Abstract AI-Helper 아이콘AI-Helper

Introduction:Helminth infection has a profound effect on the immune system. However, the precise nature of the immune changes that are elicited by helminth infection have not been sufficiently characterized. Furthermore, the reversibility of these changes after treatment has not been documented suff...

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참고문헌 (39)

  1. 1. Bundy DA , de Silva NR . Can we deworm this wormy world? Br Med Bull . 1998 ; 54 ( 2 ): 421 – 32 . PubMed PMID: 9830207 . 9830207 

  2. 2. Bundy DA , Medley GF . Immuno-epidemiology of human geohelminthiasis: ecological and immunological determinants of worm burden . Parasitology . 1992 ; 104 Suppl : S105 – 19 . PubMed PMID: 1589298 . 1589298 

  3. 3. Chan MS . The global burden of intestinal nematode infections--fifty years on . Parasitol Today . 1997 ; 13 ( 11 ): 438 – 43 . PubMed PMID: 15275146 . 15275146 

  4. 4. Araujo MI , de Jesus AR , Bacellar O , Sabin E , Pearce E , Carvalho EM . Evidence of a T helper type 2 activation in human schistosomiasis . Eur J Immunol . 1996 ; 26 ( 6 ): 1399 – 403 . PubMed PMID: 8647223 . doi: 10.1002/eji.1830260633 8647223 

  5. 5. Maizels RM , Bundy DA , Selkirk ME , Smith DF , Anderson RM . Immunological modulation and evasion by helminth parasites in human populations . Nature . 1993 ; 365 ( 6449 ): 797 – 805 . PubMed PMID: 8413664 . doi: 10.1038/365797a0 8413664 

  6. 6. Montenegro SM , Miranda P , Mahanty S , Abath FG , Teixeira KM , Coutinho EM , Brinkman J , Goncalves I , Domingues LA , Domingues AL , Sher A , Wynn TA . Cytokine production in acute versus chronic human Schistosomiasis mansoni: the cross-regulatory role of interferon-gamma and interleukin-10 in the responses of peripheral blood mononuclear cells and splenocytes to parasite antigens . J Infect Dis . 1999 ; 179 ( 6 ): 1502 – 14 . PubMed PMID: 10228073 . doi: 10.1086/314748 10228073 

  7. 7. Sher A , Gazzinelli RT , Oswald IP , Clerici M , Kullberg M , Pearce EJ , Berzofsky JA , Mosmann TR , James SL , Morse HC 3rd . Role of T-cell derived cytokines in the down-regulation of immune responses in parasitic and retroviral infection . Immunol Rev . 1992 ; 127 : 183 – 204 . PubMed PMID: 1354651 . 1354651 

  8. 8. Yazdanbakhsh M . Common features of T cell reactivity in persistent helminth infections: lymphatic filariasis and schistosomiasis . Immunol Lett . 1999 ; 65 ( 1-2 ): 109 – 15 . PubMed PMID: 10065636 . 10065636 

  9. 9. Kalinkovich A , Weisman Z , Greenberg Z , Nahmias J , Eitan S , Stein M , Bentwich Z . Decreased CD4 and increased CD8 counts with T cell activation is associated with chronic helminth infection . Clin Exp Immunol . 1998 ; 114 ( 3 ): 414 – 21 . PubMed PMID: 9844052 . Pubmed Central PMCID: PMC1905129 . 9844052 

  10. 10. Messele T , Abdulkadir M , Fontanet AL , Petros B , Hamann D , Koot M , Roos MT , Schellekens PT , Miedema F , Rinke de Wit TF . Reduced naive and increased activated CD4 and CD8 cells in healthy adult Ethiopians compared with their Dutch counterparts . Clin Exp Immunol . 1999 ; 115 ( 3 ): 443 – 50 . PubMed PMID: 10193416 . Pubmed Central PMCID: PMC1905237 . 10193416 

  11. 11. Grogan JL , Kremsner PG , Deelder AM , Yazdanbakhsh M . Antigen-specific proliferation and interferon-gamma and interleukin-5 production are down-regulated during Schistosoma haematobium infection . J Infect Dis . 1998 ; 177 ( 5 ): 1433 – 7 . PubMed PMID: 9593042 . 9593042 

  12. 12. Sabin EA , Araujo MI , Carvalho EM , Pearce EJ . Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni . J Infect Dis . 1996 ; 173 ( 1 ): 269 – 72 . PubMed PMID: 8537675 . 8537675 

  13. 13. Borkow G , Leng Q , Weisman Z , Stein M , Galai N , Kalinkovich A , Bentwich Z . Chronic immune activation associated with intestinal helminth infections results in impaired signal transduction and anergy . J Clin Invest . 2000 ; 106 ( 8 ): 1053 – 60 . PubMed PMID: 11032865 . Pubmed Central PMCID: 314342 . doi: 10.1172/JCI10182 11032865 

  14. 14. Villa OF , Kuhn RE . Mice infected with the larvae of Taenia crassiceps exhibit a Th2-like immune response with concomitant anergy and downregulation of Th1-associated phenomena . Parasitology . 1996 ; 112 ( Pt 6 ): 561 – 70 . PubMed PMID: 8684830 . 8684830 

  15. 15. Bentwich Z . Good worms or bad worms: do worm infections affect the epidemio-logical patterns of other diseases? Parasitol Today . 2000 ; 16 ( 7 ): 312 PubMed PMID: 10858652 . 10858652 

  16. 16. Bentwich Z , Kalinkovich A , Weisman Z , Borkow G , Beyers N , Beyers AD . Can eradication of helminthic infections change the face of AIDS and tuberculosis? Immunol Today . 1999 ; 20 ( 11 ): 485 – 7 . PubMed PMID: 10529774 . 10529774 

  17. 17. Soboslay PT , Geiger SM , Weiss N , Banla M , Luder CG , Dreweck CM , Batchassi E , Boatin BA , Stadler A , Schulz-Key H . The diverse expression of immunity in humans at distinct states of Onchocerca volvulus infection . Immunology . 1997 ; 90 ( 4 ): 592 – 9 . PubMed PMID: 9176114 . Pubmed Central PMCID: PMC1456700 . 9176114 

  18. 18. Bentwich Z , Weisman Z. , Grossman Z. , Galai N , and Kalinkovich A . Pathogenesis of AIDS in Africa: lessons from the Ethiopian immigrants in Israel . Immunologist . 1997 ; 5 : 21 – 26 

  19. 19. Bentwich Z , Kalinkovich A , Weisman Z . Immune activation is a dominant factor in the pathogenesis of African AIDS . Immunol Today . 1995 ; 16 ( 4 ): 187 – 91 . PubMed PMID: 7734046 . 7734046 

  20. 20. Bentwich Z , Weisman Z , Moroz C , Bar-Yehuda S , Kalinkovich A . Immune dysregulation in Ethiopian immigrants in Israel: relevance to helminth infections? Clin Exp Immunol . 1996 ; 103 ( 2 ): 239 – 43 . PubMed PMID: 8565306 . Pubmed Central PMCID: PMC2200340 . 8565306 

  21. 21. Bentwich Z , Kalinkovich A , Weisman Z , Grossman Z . Immune activation in the context of HIV infection . Clin Exp Immunol . 1998 ; 111 ( 1 ): 1 – 2 . PubMed PMID: 9472654 . Pubmed Central PMCID: PMC1904872 . 9472654 

  22. 22. Shapira-Nahor O , Kalinkovich A , Weisman Z , Greenberg Z , Nahmias J , Shapiro M , Panet A , Bentwich Z . Increased susceptibility to HIV-1 infection of peripheral blood mononuclear cells from chronically immune-activated individuals . AIDS . 1998 ; 12 ( 13 ): 1731 – 3 . PubMed PMID: 9764802 . 9764802 

  23. 23. Borkow G , Bentwich Z . Eradication of helminthic infections may be essential for successful vaccination against HIV and tuberculosis . Bull World Health Organ . 2000 ; 78 ( 11 ): 1368 – 9 . PubMed PMID: 11143198 . Pubmed Central PMCID: PMC2560630 . 11143198 

  24. 24. Borkow G , Weisman Z , Leng Q , Stein M , Kalinkovich A , Wolday D , Bentwich Z . Helminths, human immunodeficiency virus and tuberculosis . Scand J Infect Dis . 2001 ; 33 ( 8 ): 568 – 71 . PubMed PMID: 11525348 . 11525348 

  25. 25. Elias D , Wolday D , Akuffo H , Petros B , Bronner U , Britton S . Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacille Calmette-Guerin (BCG) vaccination . Clin Exp Immunol . 2001 ; 123 ( 2 ): 219 – 25 . PubMed PMID: 11207651 . Pubmed Central PMCID: 1905995 . 11207651 

  26. 26. Nahmias J , Greenberg Z , Berger SA , Hornstein L , Bilgury B , Abel B , Kutner S . Health profile of Ethiopian immigrants in Israel: an overview . Isr J Med Sci . 1993 ; 29 ( 6-7 ): 338 – 43 . PubMed PMID: 8349445 . 8349445 

  27. 27. Knight WB , Hiatt RA , Cline BL , Ritchie LS . A modification of the formol-ether concentration technique for increased sensitivity in detecting Schistosoma mansoni eggs . Am J Trop Med Hyg . 1976 ; 25 ( 6 ): 818 – 23 . PubMed PMID: 1008127 . 1008127 

  28. 28. Roberts M , Butterworth AE , Kimani G , Kamau T , Fulford AJ , Dunne DW , Ouma JH , Sturrock RF . Immunity after treatment of human schistosomiasis: association between cellular responses and resistance to reinfection . Infect Immun . 1993 ; 61 ( 12 ): 4984 – 93 . PubMed PMID: 8225573 . Pubmed Central PMCID: 281273 . 8225573 

  29. 29. Feldmeier H , Gastl GA , Poggensee U , Daffalla AA , Nogueira-Queiroz JA , Capron A , Peter HH . Immune response in chronic Schistosomiasis haematobium and mansoni. Reversibility of alterations after anti-parasitic treatment with praziquantel . Scand J Immunol . 1988 ; 28 ( 2 ): 147 – 55 . PubMed PMID: 3137653 . 3137653 

  30. 30. Williams MA , Rhoades CJ , Newland AC , Kelsey SM . The potential for monocyte-mediated immunotherapy during infection and malignancy--Part II: in vivo activation by exogenous cytokines and clinical applications . Leuk Lymphoma . 1999 ; 34 ( 3-4 ): 207 – 30 . PubMed PMID: 10439359 . doi: 10.3109/10428199909050947 10439359 

  31. 31. Mosmann TR , Sad S . The expanding universe of T-cell subsets: Th1, Th2 and more . Immunol Today . 1996 ; 17 ( 3 ): 138 – 46 . PubMed PMID: 8820272 . 8820272 

  32. 32. Williams ME , Montenegro S , Domingues AL , Wynn TA , Teixeira K , Mahanty S , Coutinho A , Sher A . Leukocytes of patients with Schistosoma mansoni respond with a Th2 pattern of cytokine production to mitogen or egg antigens but with a Th0 pattern to worm antigens . J Infect Dis . 1994 ; 170 ( 4 ): 946 – 54 . PubMed PMID: 7930740 . 7930740 

  33. 33. Fallon PG , Smith P , Dunne DW . Type 1 and type 2 cytokine-producing mouse CD4+ and CD8+ T cells in acute Schistosoma mansoni infection . Eur J Immunol . 1998 ; 28 ( 4 ): 1408 – 16 . PubMed PMID: 9565381 . doi: 10.1002/(SICI)1521-4141(199804)28:04 3.0.CO;2-H 9565381 

  34. 34. Grzych JM , Pearce E , Cheever A , Caulada ZA , Caspar P , Heiny S , Lewis F , Sher A . Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni . J Immunol . 1991 ; 146 ( 4 ): 1322 – 7 . PubMed PMID: 1825109 . 1825109 

  35. 35. Mwatha JK , Kimani G , Kamau T , Mbugua GG , Ouma JH , Mumo J , Fulford AJ , Jones FM , Butterworth AE , Roberts MB , Dunne DW . High levels of TNF, soluble TNF receptors, soluble ICAM-1, and IFN-gamma, but low levels of IL-5, are associated with hepatosplenic disease in human schistosomiasis mansoni . J Immunol . 1998 ; 160 ( 4 ): 1992 – 9 . PubMed PMID: 9469463 . 9469463 

  36. 36. Wolday D , Mayaan S , Mariam ZG , Berhe N , Seboxa T , Britton S , Galai N , Landay A , Bentwich Z . Treatment of intestinal worms is associated with decreased HIV plasma viral load . J Acquir Immune Defic Syndr . 2002 ; 31 ( 1 ): 56 – 62 . PubMed PMID: 12352151 . 12352151 

  37. 37. Walson JL , Herrin BR , John-Stewart G . Deworming helminth co-infected individuals for delaying HIV disease progression . Cochrane Database Syst Rev . 2009 ( 3 ): CD006419 PubMed PMID: 19588389 . Pubmed Central PMCID: 2871762 . 10.1002/14651858.CD006419.pub3 19588389 

  38. 38. Lawn SD , Karanja DM , Mwinzia P , Andove J , Colley DG , Folks TM , Secor WE . The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals . AIDS . 2000 ; 14 ( 16 ): 2437 – 43 . PubMed PMID: 11101053 . 11101053 

  39. 39. Modjarrad K , Zulu I , Redden DT , Njobvu L , Lane HC , Bentwich Z , Vermund SH . Treatment of intestinal helminths does not reduce plasma concentrations of HIV-1 RNA in coinfected Zambian adults . J Infect Dis . 2005 ; 192 ( 7 ): 1277 – 83 . PubMed PMID: 16136473 . Pubmed Central PMCID: PMC2730764 . doi: 10.1086/444543 16136473 

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