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Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials 원문보기

Medicina oral, patología oral y cirugía bucal, v.24 no.1, 2019년, pp.e61 - e69  

Mendes, Mário-Luis-Tavares (MSc, Investigative Pathology Laboratory, Federal University of Sergipe, Brazil) ,  do Nascimento-Júnior, Edmundo-Marques (MSc, Investigative Pathology Laboratory, Federal University of Sergipe, Brazil) ,  Reinheimer, Daniele-Machado (MSc, Investigative Pathology Laboratory, Federal University of Sergipe, Brazil) ,  Martins-Filho, Paulo-Ricardo-Saquete (PhD, Investigative Pathology Laboratory, Federal University of Sergipe, Brazil)

Abstract AI-Helper 아이콘AI-Helper

BackgroundBromelain is a cysteine protease isolated from pineapple with a range of biological properties including platelet aggregation inhibition and anti-inflammatory effects. Recent studies have evaluated the clinical implications of bromelain in reducing postoperative inflammatory complications ...

참고문헌 (35)

  1. 1 Rathnavelu V Alitheen NB Sohila S Kanagesan S Ramesh R Potential role of bromelain in clinical and therapeutic applications Biomed reports 2016 5 283 8 27602208 

  2. 2 Taussig SJ Batkin S Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update J Ethnopharmacol 1988 22 191 203 3287010 

  3. 3 Dutta S Bhattacharyya D Enzymatic, antimicrobial and toxicity studies of the aqueous extract of Ananas comosus (pineapple) crown leaf J Ethnopharmacol 2013 150 451 7 24076462 

  4. 4 Maurer HR Bromelain: biochemistry, pharmacology and medical use Cell Mol life Sci 2001 58 1234 45 11577981 

  5. 5 Castell JV Friedrich G Kuhn CS Poppe GE Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake Am J Physiol 1997 273 G139 46 9252520 

  6. 6 Shoham Y Krieger Y Tamir E Silberstein E Bogdanov-Berezovsky A Haik J Bromelain-based enzymatic debridement of chronic wounds: A preliminary report Int Wound J 2018 15 769 775 29696785 

  7. 7 Schulz A Fuchs PC Rothermundt I Hoffmann A Rosenberg L Shoham Y Enzymatic debridement of deeply burned faces: Healing and early scarring based on tissue preservation compared to traditional surgical debridement Burns 2017 43 1233 43 28363663 

  8. 8 Conrozier T Mathieu P Bonjean M Marc JF Renevier JL Balblanc JC A complex of three natural anti-inflammatory agents provides relief of osteoarthritis pain Altern Ther Health Med 2014 20 32 7 24473984 

  9. 9 Walker AF Bundy R Hicks SM Middleton RW Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults Phytomedicine 2002 9 681 6 12587686 

  10. 10 Jayachandran S Khobre P Efficacy of Bromelain along with Trypsin, Rutoside Trihydrate Enzymes and Diclofenac Sodium Combination Therapy for the treatment of TMJ Osteoarthritis - A Randomised Clinical Trial J Clin diagnostic Res 2017 11 ZC09 ZC11 

  11. 11 Majid OW Al-Mashhadani BA Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: A randomized, double-blind, placebo-controlled clinical trial J Oral Maxillofac Surg 2014 72 1043 8 24589242 

  12. 12 Tan Y Li P Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor Oncol Lett 2018 15 2962 6 29435025 

  13. 13 de la Barrera-Nunez M Yanez-Vico R Batista-Cruzado A Heurtebise-Saavedra J Castillo-de Oyague R Torres-Lagares D Prospective double-blind clinical trial evaluating the effectiveness of Bromelain in the third molar extraction postoperative period Med Oral Patol Oral y Cir Bucal 2014 19 e157 62 24316697 

  14. 14 de Santana-Santos T de Souza-Santos JAS Martins-Filho PRS da Silva LCF de Oliveira E Silva ED Gomes ACA Prediction of postoperative facial swelling, pain and trismus following third molar surgery based on preoperative variables Med Oral Patol Oral Cir Bucal 2013 18 e65 70 23229245 

  15. 15 McGrath C Comfort MB Lo ECM Luo Y Changes in life quality following third molar surgery--the immediate postoperative period Br Dent J 2003 194 265 8 12658303 

  16. 16 Moher D Liberati A Tetzlaff J Altman DG Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Int J Surg 2010 8 336 41 20171303 

  17. 17 Higgins JPT Altman DG Gøtzsche PC Jüni P Moher D Oxman AD The Cochrane Collaboration's tool for assessing risk of bias in randomised trials BMJ 2011 343 d5928 22008217 

  18. 18 Cochran WG The Combination of Estimates from Different Experiments Biometrics 1954 10 101 

  19. 19 Higgins JPT Deeks JJ Altman DG Chapter 16: Special topics in statistics. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 2011 The Cochrane Collaboration 

  20. 20 Cochran WG The Combination of Estimates from Different Experiments Biometrics 1954 10 101 

  21. 21 Higgins JPT Thompson SG Quantifying heterogeneity in a meta-analysis Stat Med 2002 21 1539 58 12111919 

  22. 22 Guyatt GH Oxman AD Vist GE Kunz R Falck-Ytter Y Alonso-Coello P GRADE: an emerging consensus on rating quality of evidence and strength of recommendations BMJ 2008 336 924 6 18436948 

  23. 23 Guyatt GH Oxman AD Kunz R Vist GE Falck-Ytter Y Schunemann HJ What is "quality of evidence" and why is it important to clinicians? BMJ 2008 336 995 8 18456631 

  24. 24 Ghensi P Cucchi A Creminelli L Tomasi C Zavan B Maiorana C Effect of Oral Administration of Bromelain on Postoperative Discomfort after Third Molar Surgery J Craniofac Surg 2017 28 e191 7 27755433 

  25. 25 Bormann KH Weber K Kloppenburg H Koch A Meiser P Gellrich NC Perioperative Bromelain Therapy after Wisdom Teeth Extraction – A Randomized, Placebo-Controlled, Double-Blinded, Three-Armed, Cross-Over Dose-Finding Study Phyther Res 2016 30 2012 9 27601419 

  26. 26 Ordesi P Pisoni L Nannei P Macchi M Borloni R Siervo S Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study Quintessence Int (Berl) 2014 45 679 84 

  27. 27 Au AHY Choi SW Cheung CW Leung YY The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis. Staffieri F, editor PLoS One 2015 10 e0127611 26053953 

  28. 28 Ong CKS Lirk P Tan CH Seymour RA An Evidence-Based Update on Nonsteroidal Anti-Inflammatory Drugs Clin Med Res [Internet] 2007 5 19 34 17456832 

  29. 29 Canellas JV dos S Ritto FG Medeiros PJD Evaluation of postoperative complications after mandibular third molar surgery with the use of platelet-rich fibrin: a systematic review and meta-analysis Int J Oral Maxillofac Surg 2017 46 1138 46 28473242 

  30. 30 Landucci A Wosny AC Uetanabaro LC Moro A Araujo MR Efficacy of a single dose of low-level laser therapy in reducing pain, swelling, and trismus following third molar extraction surgery Int J Oral Maxillofac Surg 2016 45 392 8 26691932 

  31. 31 Gaspani L Limiroli E Ferrario P Bianchi M In vivo and in vitro Effects of Bromelain on PGE2 and SP Concentrations in the Inflammatory Exudate in Rats Pharmacology 2002 65 83 6 11937778 

  32. 32 Kumakura S Yamashita M Tsurufuji S Effect of bromelain on kaolin-induced inflammation in rats Eur J Pharmacol 1988 150 295 301 3046953 

  33. 33 Lotz-Winter H On the pharmacology of bromelain: an update with special regard to animal studies on dose-dependent effects Planta Med 1990 56 249 53 2203073 

  34. 34 Hale LP Greer PK Trinh CT James CL Proteinase activity and stability of natural bromelain preparations Int Immunopharmacol 2005 5 783 93 15710346 

  35. 35 de Lencastre Novaes LC Jozala AF Lopes AM de Carvalho Santos-Ebinuma V Mazzola PG Pessoa Junior A Stability, purification, and applications of bromelain: A review Biotechnol Prog 2016 32 5 13 26518672 

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