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[해외논문] IDH1-dependent α-KG regulates brown fat differentiation and function by modulating histone methylation

Metabolism : clinical and experimental, v.105, 2020년, pp.154173 -   

Kang, Hyun Sup (Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Lee, Jae Ho (Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Oh, Kyoung-Jin (Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Lee, Eun Woo (Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Han, Baek Soo (Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Park, Kun-Young (Biomedical Science and Engineering Interdisciplinary Program, KAIST) ,  Suh, Jae Myoung (Biomedical Science and Engineering Interdisciplinary Program, KAIST) ,  Min, Jeong-Ki (Metabolic Regulation Research Center, Korea Research Institute of Bioscience) ,  Chi, Seung-Wook ,  Lee, Sang Chul ,  Bae, Kwang-Hee ,  Kim, Won Kon

Abstract AI-Helper 아이콘AI-Helper

Abstract Objective Brown adipocytes play important roles in the regulation of energy homeostasis by uncoupling protein 1-mediated non-shivering thermogenesis. Recent studies suggest that brown adipocytes as novel therapeutic targets for combating obesity and associated diseases, such as type II dia...

Keyword

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