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NTIS 바로가기International journal of pharmaceutics, v.581, 2020년, pp.119287 -
Na, Young-Guk (College of Pharmacy and Institute of Drug Research and Development, Chungnam National University) , Pham, Thi Mai Anh (College of Pharmacy and Institute of Drug Research and Development, Chungnam National University) , Byeon, Jin-Ju (College of Pharmacy and Institute of Drug Research and Development, Chungnam National University) , Kim, Min-Ki (College of Pharmacy and Institute of Drug Research and Development, Chungnam National University) , Han, Min-Gu (College of Pharmacy and Institute of Drug Research and Development, Chungnam National University) , Baek, Jong-Suep (Department of Herbal Medicine Resource, Kangwon National University) , Lee, Hong-Ki (College of Pharmacy and Institute of Drug Research and Development, Chungnam National University) , Cho, Cheong-Weon (College of Pharmacy and Institute of Drug Research and Development, Chungnam)
Abstract In this study, we developed ticagrelor-dispersed nanosuspension (TCG-NSP) to enhance the dissolution and oral bioavailability of ticagrelor (TCG) through a statistical design approach. TCG, a reversible P2Y12 receptor antagonist, is classified as a biopharmaceutics classification system (B...
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