[논문]Task-dependent effects of intracranial hippocampal stimulation on human memory and hippocampal theta power

Jun, Soyeon; Lee, Sang Ah; Kim, June Sic; Jeong, Woorim; Chung, Chun Kee

doi:10.1016/j.brs.2020.01.013

[해외논문] Task-dependent effects of intracranial hippocampal stimulation on human memory and hippocampal theta power 원문보기

Brain stimulation, v.13 no.3, 2020년, pp.603 - 613

Jun, Soyeon (Department of Brain & Cognitive Sciences, Seoul National University) , Lee, Sang Ah (Department of Bio & Brain Engineering, Korea Advanced Institute of Science and Technology) , Kim, June Sic (Department of Brain & Cognitive Sciences, Seoul National University) , Jeong, Woorim (Neuroscience Research Institute, Seoul National University College of Medicine) , Chung, Chun Kee (Department of Brain & Cognitive Sciences, Seoul National University)

Abstract ▼ AI-Helper

Abstract Background Despite its potential to revolutionize the treatment of memory dysfunction, the efficacy of direct electrical hippocampal stimulation for memory performance has not yet been well characterized. One of the main challenges to cross-study comparison in this area of research is the diversity of the cognitive tasks used to measure memory performance. Objective We hypothesized that the tasks that differentially engage the hippocampus may be differentially influenced by hippocampal stimulation and the behavioral effects would be related to the underlying hippocampal activity. Methods To investigate this issue, we recorded intracranial EEG from and directly applied stimulation to the hippocampus of 10 epilepsy patients while they performed two different verbal memory tasks – a word pair associative memory task and a single item memory task. Results Hippocampal stimulation modulated memory performance in a task-dependent manner, improving associative memory performance, while impairing item memory performance. In addition, subjects with poorer baseline cognitive function improved much more with stimulation. iEEG recordings from the hippocampus during non-stimulation encoding blocks revealed that the associative memory task elicited stronger theta oscillations than did item memory and that stronger theta power was related to memory performance. Conclusions We show here for the first time that stimulation-induced associative memory enhancement was linked to increased theta power during retrieval. These results suggest that hippocampal stimulation enhances associative memory but not item memory because it engages more hippocampal theta activity and that, in general, increasing hippocampal theta may provide a neural mechanism for successful memory enhancement. Highlights The present study addressed the differential effects of direct hippocampal stimulation on memory performance. Only associative memory was enhanced by direct electrical stimulation to the hippocampus. This memory enhancement was linked to increased hippocampal theta power. Effect of stimulation on memory depends on the underlying brain activity elicited by the task.

Keyword

참고문헌 (70)

Hippocampus Tulving 8 3 198 1998 10.1002/(SICI)1098-1063(1998)8:3<198::AID-HIPO2>3.0.CO;2-G Episodic and declarative memory: role of the hippocampus

상세보기
Annu Rev Neurosci Eichenbaum 30 123 2007 10.1146/annurev.neuro.30.051606.094328 The medial temporal lobe and recognition memory

상세보기
J Neurosci Goyal 38 19 4471 2018 10.1523/JNEUROSCI.3049-17.2018 Electrical stimulation in Hippocampus and entorhinal cortex impairs spatial and temporal memory

상세보기
Neuron Jacobs 92 5 983 2016 10.1016/j.neuron.2016.10.062 Direct electrical stimulation of the human entorhinal region and Hippocampus impairs memory

상세보기
Neuroscience Lacruz 170 2 623 2010 10.1016/j.neuroscience.2010.06.042 Single pulse electrical stimulation of the hippocampus is sufficient to impair human episodic memory

상세보기
N Engl J Med Suthana 366 6 502 2012 10.1056/NEJMoa1107212 Memory enhancement and deep-brain stimulation of the entorhinal area

상세보기
Brain Stimul Fell 6 3 270 2013 10.1016/j.brs.2012.08.001 Memory modulation by weak synchronous deep brain stimulation: a pilot study

상세보기
J Neural Eng Berger 8 4 2011 10.1088/1741-2560/8/4/046017 A cortical neural prosthesis for restoring and enhancing memory

상세보기
IEEE Trans Neural Syst Rehabil Eng Hampson 20 2 184 2012 10.1109/TNSRE.2012.2189163 A nonlinear model for hippocampal cognitive prosthesis: memory facilitation by hippocampal ensemble stimulation

상세보기
Front Hum Neurosci Jun 13 23 2019 10.3389/fnhum.2019.00023 Direct stimulation of human Hippocampus during verbal associative encoding enhances subsequent memory recollection

상세보기
Trends Cognit Sci Battaglia 15 7 310 2011 The hippocampus: hub of brain network communication for memory
Eichenbaum x 583 2001
Hippocampus Squire 8 3 205 1998 10.1002/(SICI)1098-1063(1998)8:3<205::AID-HIPO3>3.0.CO;2-I Episodic memory, semantic memory, and amnesia

상세보기
Behav Brain Sci Eichenbaum 17 3 449 1994 10.1017/S0140525X00035391 2 functional components of the hippocampal memory system

상세보기
J Mem Lang Kroll 35 2 176 1996 Cohesion failure as a source of memory illusions

상세보기
Neuropsychologia Turriziani 42 4 426 2004 10.1016/j.neuropsychologia.2003.10.003 Recognition memory for single items and for associations in amnesic patients

상세보기
Cognit Affect Behav Neurosci Giovanello 3 3 186 2003 10.3758/CABN.3.3.186 Disproportionate deficit in associative recognition relative to item recognition in global amnesia

상세보기
Hippocampus Baxter 11 1 61 2001 10.1002/1098-1063(2001)11:1<61::AID-HIPO1021>3.0.CO;2-Z Opposite relationship of hippocampal and rhinal cortex damage to delayed nonmatching-to-sample deficits in monkeys

상세보기
J Neurosci Zola-Morgan 6 10 2950 1986 10.1523/JNEUROSCI.06-10-02950.1986 Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

상세보기
Hippocampus Pascalis 9 6 609 1999 10.1002/(SICI)1098-1063(1999)9:6<609::AID-HIPO1>3.0.CO;2-A Neonatal aspiration lesions of the hippocampal formation impair visual recognition memory when assessed by paired-comparison task but not by delayed nonmatching-to-sample task

상세보기
Nat Neurosci Kreiman 3 9 946 2000 10.1038/78868 Category-specific visual responses of single neurons in the human medial temporal lobe

상세보기
Nat Rev Neurosci Brown 2 1 51 2001 10.1038/35049064 Recognition memory: what are the roles of the perirhinal cortex and hippocampus?

상세보기
Hippocampus Giovanello 14 1 5 2004 10.1002/hipo.10182 A critical role for the anterior hippocampus in relational memory: evidence from an fMRI study comparing associative and item recognition

상세보기
Hippocampus Mayes 14 6 763 2004 10.1002/hipo.10211 Associative recognition in a patient with selective hippocampal lesions and relatively normal item recognition

상세보기
Curr Biol Ezzyat 27 9 1251 2017 10.1016/j.cub.2017.03.028 Direct brain stimulation modulates encoding states and memory performance in humans

상세보기
Jun 13 23 2019 Direct stimulation of human Hippocampus during verbal associative encoding enhances subsequent memory recollection
Nature Rutishauser 464 7290 903 2010 10.1038/nature08860 Human memory strength is predicted by theta-frequency phase-locking of single neurons

상세보기
Nat Neurosci Buzsaki 16 2 130 2013 10.1038/nn.3304 Memory, navigation and theta rhythm in the hippocampal-entorhinal system

상세보기
Hippocampus Lega 22 4 748 2012 10.1002/hipo.20937 Human hippocampal theta oscillations and the formation of episodic memories

상세보기
Behav Neurosci Hasselmo 119 1 342 2005 10.1037/0735-7044.119.1.342 The role of hippocampal regions CA3 and CA1 in matching entorhinal input with retrieval of associations between objects and context: theoretical comment on Lee et al

상세보기
Learn Mem Hasselmo 14 11 782 2007 10.1101/lm.686607 Arc length coding by interference of theta frequency oscillations may underlie context-dependent hippocampal unit data and episodic memory function

상세보기
Cerebr Cortex Axmacher 18 12 2868 2008 10.1093/cercor/bhn045 Interaction of working memory and long-term memory in the medial temporal lobe

상세보기
Behav Neurosci Atri 118 1 223 2004 10.1037/0735-7044.118.1.223 Blockade of central cholinergic receptors impairs new learning and increases proactive interference in a word paired-associate memory task

상세보기
Neuroimage de Vanssay-Maigne 58 4 1131 2011 10.1016/j.neuroimage.2011.06.086 Modulation of encoding and retrieval by recollection and familiarity: mapping the medial temporal lobe networks

상세보기
Neurol Res Shin 31 7 692 2009 10.1179/174313209X389848 Changes in neuropsychological functioning following temporal lobectomy in patients with temporal lobe epilepsy

상세보기
J Neurosci Methods Maris 164 1 177 2007 10.1016/j.jneumeth.2007.03.024 Nonparametric statistical testing of EEG- and MEG-data

상세보기
Philos Trans R Soc Lond B Biol Sci Jacobs 369 1635 20130304 2014 10.1098/rstb.2013.0304 Hippocampal theta oscillations are slower in humans than in rodents: implications for models of spatial navigation and memory

상세보기
Nat Neurosci Watrous 16 3 349 2013 10.1038/nn.3315 Frequency-specific network connectivity increases underlie accurate spatiotemporal memory retrieval

상세보기
Neurosci Biobehav Rev Nyhus 34 7 1023 2010 10.1016/j.neubiorev.2009.12.014 Functional role of gamma and theta oscillations in episodic memory

상세보기
J Neurosci Lee 38 13 3265 2018 10.1523/JNEUROSCI.3216-17.2018 Electrophysiological signatures of spatial boundaries in the human subiculum

상세보기
Hippocampus Hasselmo 15 7 936 2005 10.1002/hipo.20116 What is the function of hippocampal theta rhythm?--Linking behavioral data to phasic properties of field potential and unit recording data

상세보기
J Neurosci Sederberg 23 34 10809 2003 10.1523/JNEUROSCI.23-34-10809.2003 Theta and gamma oscillations during encoding predict subsequent recall

상세보기
Science Wang 345 6200 1054 2014 10.1126/science.1252900 Targeted enhancement of cortical-hippocampal brain networks and associative memory

상세보기
Hippocampus Wang 25 8 877 2015 10.1002/hipo.22416 Long-lasting enhancements of memory and hippocampal-cortical functional connectivity following multiple-day targeted noninvasive stimulation

상세보기
Brain Res Matzen 1624 286 2015 10.1016/j.brainres.2015.07.036 Effects of non-invasive brain stimulation on associative memory

상세보기
J Cognit Neurosci Tambini 30 10 1452 2018 10.1162/jocn_a_01300 Hippocampal-targeted theta-burst stimulation enhances associative memory formation

상세보기
Brain Cognit Silvanto 119 32 2017 10.1016/j.bandc.2017.09.007 Common framework for "virtual lesion" and state-dependent TMS: the facilitatory/suppressive range model of online TMS effects on behavior

상세보기
Curr Opin Neurobiol Davachi 16 6 693 2006 10.1016/j.conb.2006.10.012 Item, context and relational episodic encoding in humans

상세보기
Trends Cognit Sci Mayes 11 3 126 2007 10.1016/j.tics.2006.12.003 Associative memory and the medial temporal lobes

상세보기
Trends Cognit Sci Diana 11 9 379 2007 10.1016/j.tics.2007.08.001 Imaging recollection and familiarity in the medial temporal lobe: a three-component model

상세보기
Front Hum Neurosci Olsen 6 146 2012 10.3389/fnhum.2012.00146 The hippocampus supports multiple cognitive processes through relational binding and comparison

상세보기
Nat Commun Staresina 10 1 1503 2019 10.1038/s41467-019-09558-3 Recollection in the human hippocampal-entorhinal cell circuitry

상세보기
Science Tamura 357 6352 687 2017 10.1126/science.aan4800 Conversion of object identity to object-general semantic value in the primate temporal cortex

상세보기
Trends Cognit Sci Silvanto 12 12 447 2008 10.1016/j.tics.2008.09.004 State-dependency in brain stimulation studies of perception and cognition

상세보기
Annu Rev Neurosci Perlmutter 29 229 2006 10.1146/annurev.neuro.29.051605.112824 Deep brain stimulation

상세보기
Brain Res Ranck 98 3 417 1975 10.1016/0006-8993(75)90364-9 Which elements are excited in electrical-stimulation of mammalian central nervous-system - Review

상세보기
Neurology Moro 59 5 706 2002 10.1212/WNL.59.5.706 The impact on Parkinson’s disease of electrical parameter settings in STN stimulation

상세보기
Neurosci Biobehav Rev Hescham 37 10 Pt 2 2666 2013 10.1016/j.neubiorev.2013.09.002 Deep brain stimulation in dementia-related disorders

상세보기
Sci Transl Med Hamani 4 142 142rv8 2012 10.1126/scitranslmed.3003722 Deep brain stimulation for psychiatric disease: contributions and validity of animal models

상세보기
J Psychiatr Res Hamani 44 11 683 2010 10.1016/j.jpsychires.2009.12.010 Effects of different stimulation parameters on the antidepressant-like response of medial prefrontal cortex deep brain stimulation in rats

상세보기
J Neurophysiol Davachi 88 2 982 2002 10.1152/jn.2002.88.2.982 Hippocampal contributions to episodic encoding: insights from relational and item-based learning

상세보기
Neuroimage Jackson 21 1 456 2004 10.1016/j.neuroimage.2003.09.050 Encoding activity in anterior medial temporal lobe supports subsequent associative recognition

상세보기
Hippocampus Kirwan 14 7 919 2004 10.1002/hipo.20014 Medial temporal lobe activation during encoding and retrieval of novel face-name pairs

상세보기
Eur J Neurosci Molle 15 5 923 2002 10.1046/j.1460-9568.2002.01921.x EEG theta synchronization conjoined with alpha desynchronization indicate intentional encoding

상세보기
Brain Behav Evol Pollen 14 1-2 67 1977 10.1159/000125576 Responses of single neurons to electrical stimulation of the surface of the visual cortex

상세보기
J Neurosci Hyman 23 37 11725 2003 10.1523/JNEUROSCI.23-37-11725.2003 Stimulation in hippocampal region CA1 in behaving rats yields long-term potentiation when delivered to the peak of theta and long-term depression when delivered to the trough

상세보기
Brain Res Pavlides 439 1-2 383 1988 10.1016/0006-8993(88)91499-0 Long-term potentiation in the dentate gyrus is induced preferentially on the positive phase of theta-rhythm

상세보기
Lezak 1026 1995 Neuropsychological assessment
Learn Mem Gold 13 5 644 2006 10.1101/lm.258406 Single-item memory, associative memory, and the human hippocampus

상세보기
Elife Titiz 6 2017 10.7554/eLife.29515 Theta-burst microstimulation in the human entorhinal area improves memory specificity

상세보기

LOADING...

활용도 분석정보

상세보기

다운로드

내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증