$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Chloroquine and COVID-19 – a potential game changer? 원문보기

Clinical medicine : journal of the Royal College of Physicians of London, v.20 no.3, 2020년, pp.278 - 281  

Sturrock, Beattie RH (ABrighton and Sussex Medical School, Brighton UK and Royal Sussex County Hospital, Brighton, UK) ,  Chevassut, Timothy JT (BBrighton and Sussex Medical School, Brighton UK and consultant haematologist, Royal Sussex County Hospital, Brighton, UK)

Abstract AI-Helper 아이콘AI-Helper

The novel coronavirus SARS-CoV-2, causing the disease COVID-19, first emerged in Wuhan, China in December 2019 and has now spread to 203 countries or territories, infected over 2 million people and caused over 133,000 deaths. There is an urgent need for specific treatments. One potential treatment i...

주제어

참고문헌 (38)

  1. World Health Organization 

  2. N Engl J Med Zhu 382 727 2020 10.1056/NEJMoa2001017 A novel coronavirus from patients with pneumonia in China, 2019 

  3. World Health Organization 

  4. JAMA Paules 323 707 2020 10.1001/jama.2020.0757 Coronavirus infections - more than just the common cold 

  5. Nat Rev Microbiol De Wit 14 523 2016 10.1038/nrmicro.2016.81 SARS and MERS: recent insights into emerging coronaviruses 

  6. Coronavirus disease (COVID-19) pandemic World Health Organization 2020 

  7. Lancet Huang 395 497 2020 10.1016/S0140-6736(20)30183-5 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China 

  8. Lancet Chen 395 507 2020 10.1016/S0140-6736(20)30211-7 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study 

  9. JAMA Wang 323 1061 2020 10.1001/jama.2020.1585 Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China 

  10. Drug Discov Ther Dong 14 58 2020 10.5582/ddt.2020.01012 Discovering drugs to treat coronavirus disease 2019 (COVID-19) 

  11. J Antimicrob Chemother Zhou 2020 COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression 

  12. J Antimicrob Chemother Al-Bari 70 1608 2015 10.1093/jac/dkv018 Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases 

  13. Antimicrob Agents Chemother Keyaerts 53 3416 2009 10.1128/AAC.01509-08 Antiviral activity of chloroquine against human coronavirus OC43 infection in newborn mice 

  14. Biochem Biophys Res Commun Keyaerts 323 264 2004 10.1016/j.bbrc.2004.08.085 In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine 

  15. Virol J Vincent 2 69 2005 10.1186/1743-422X-2-69 Chloroquine is a potent inhibitor of SARS coronavirus infection and spread 

  16. Antivir Chem Chemother Barnard 17 275 2006 10.1177/095632020601700505 Evaluation of immunomodulators, interferons and known in vitro SARS-CoV inhibitors for inhibition of SARS-CoV replication in BALB/c mice 

  17. Lancet Infect Dis Savarino 3 722 2003 10.1016/S1473-3099(03)00806-5 Effects of chloroquine on viral infections: An old drug against today's diseases 

  18. Int J Antimicrob Agents Rolain 30 297 2007 10.1016/j.ijantimicag.2007.05.015 Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century 

  19. Proc Natl Acad Sci USA Simmons 101 4240 2004 10.1073/pnas.0306446101 Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry 

  20. Cell Discov Liu 6 16 2020 10.1038/s41421-020-0156-0 Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro 

  21. Nat Rev Rheumatol Schrezenmeier 16 155 2020 10.1038/s41584-020-0372-x Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology 

  22. Cell Res Wang 30 269 2020 10.1038/s41422-020-0282-0 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro 

  23. Clin Infect Dis Yao 2020 10.1093/cid/ciaa237 In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 

  24. Molecules Nqoro 22 2268 2017 10.3390/molecules22122268 Quinoline-based hybrid compounds with antimalarial activity 

  25. Chin Med J (Engl) Fan 2020 10.1097/CM9.0000000000000797 Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus (2019-nCoV) related coronavirus model 

  26. Biosci Trends Gao 14 72 2020 10.5582/bst.2020.01047 Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies 

  27. J Crit Care Cortegiani 2020 A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 

  28. J Zhejiang Univ (Med Sci) Chen 2020 A pilot study of hydroxychloroquine in treatment of patients with common coronavirus disease-19 (COVID-19) 

  29. Int J Antimicrob Agents Gautret 2020 10.1016/j.ijantimicag.2020.105949 Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial 

  30. Trump 

  31. Int J Antimicrob Agents Colson 2020 10.1016/j.ijantimicag.2020.105923 Chloroquine for the 2019 novel coronavirus SARS-CoV-2 

  32. Ann Rheum Dis Aviña-Zubieta 57 582 1998 10.1136/ard.57.10.582 Long term effectiveness of antimalarial drugs in rheumatic diseases 

  33. Ann Rheum Dis Ruiz-Irastorza 69 20 2010 10.1136/ard.2008.101766 Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: A systematic review 

  34. Zhonghua Jie He He Hu Xi Za Zhi [Chinese Journal of Tuberculosis and Respiratory Diseases] 43 185 2020 

  35. Lupus Foundation of America 

  36. Int J Antimicrob Agents Sahraei 2019 Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine 

  37. Lancet Glob Health Mitjà 2020 10.1016/S2214-109X(20)30114-5 Use of antiviral drugs to reduce COVID-19 transmission 

  38. Clin Med Lake 20 124 2020 10.7861/clinmed.2019-coron What we know so far: COVID-19 current clinical knowledge and research 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로