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Intranasal administration of conditioned medium derived from mesenchymal stem cells-differentiated oligodendrocytes ameliorates experimental autoimmune encephalomyelitis

Journal of chemical neuroanatomy, v.106, 2020년, pp.101792 -   

Borhani-Haghighi, Maryam (Department of Anatomy, School of Medicine, Tehran University of Medical Sciences) ,  Mohamadi, Yousef (Department of Anatomy, School of Medicine, Ilam University of Medical Sciences)

Abstract AI-Helper 아이콘AI-Helper

Abstract In multiple sclerosis, myelin sheaths around the axons are degenerated due to uncontrolled inflammation in the central nervous system. Oligodendrocytes (OLs) are myelin-forming cells that secrete trophic factors necessary for myelin protection. Beneficial features of conditioned medium (CM...

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