제안 방법

• In this study, we treated tomato extract in C6 cells, rat primary astrocytes, and PC12 cells, and investigated the effects of tomato on NGF production and neurite outgrowth. To examine the effect of tomato extract on peripheral and midbrain auditory pathway functions, we analyzed the auditory brainstem response (ABR) and the auditory middle latency response (AMLR) in diabetic mice.
• Some studies have been reported that chronic diabetes can induce AN, and that neuronal abnormalities in diabetes can be ameliorated by treatment of neurotrophic factors such as nerve growth factor (NGF). The purpose of the present study was to evaluate the effect of tomato (Solanum lycopersicum) extract on auditory nerve conduction and hearing loss due to diabetic neuropathy via NGF regulation.
• In this study, we treated tomato extract in C6 cells, rat primary astrocytes, and PC12 cells, and investigated the effects of tomato on NGF production and neurite outgrowth. To examine the effect of tomato extract on peripheral and midbrain auditory pathway functions, we analyzed the auditory brainstem response (ABR) and the auditory middle latency response (AMLR) in diabetic mice.