Keratin Hydrolysates, Process for Their Production and Cosmetic Composition Containing the Same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
공개
국제특허분류(IPC7판)
A61K-008/65
C12P-021/06
A61Q-019/00
A61Q-005/12
출원번호
US-0666409
(2008-06-30)
공개번호
US-0196302
(2010-08-05)
우선권정보
BR-PI 0705059-3(2007-06-28)
국제출원번호
PCT/BR2008/000180
(2008-06-30)
발명자
/ 주소
Vermelho, Alane Beatriz
Vazquez Villa, Ana Lúcia
de Almeida, Ana Maria Mazotto
de Souza Dias, Edilma Paraguai
dos Santos, Elizabete Pereira
대리인 / 주소
ALSTON & BIRD LLP
인용정보
피인용 횟수 :
0인용 특허 :
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초록▼
This present invention provides a process for keratin hydrolysis by means of microbiological and/or enzymatic processes. In particular, the keratin is derived from feathers of animals, such as chicken and are submitted to hydrolysis by a strain of Bacillus sp. The hydrolysates have molecular weight
This present invention provides a process for keratin hydrolysis by means of microbiological and/or enzymatic processes. In particular, the keratin is derived from feathers of animals, such as chicken and are submitted to hydrolysis by a strain of Bacillus sp. The hydrolysates have molecular weight lower than 500 Da, which makes them ideal for cosmetic applications, particularly for applications in compositions for treatment of hair fiber re-building.
대표청구항▼
1. Process of keratin hydrolysis characterized by comprising the steps of: a) mixing: a.1) from about 106 to about 5×107 cells/mL of at least one species of bacteria B. subtilis; a.2) from about 0.1% to about 5% w/w of a material containing keratin fibers; a.3) from about 0.005% to about 10%
1. Process of keratin hydrolysis characterized by comprising the steps of: a) mixing: a.1) from about 106 to about 5×107 cells/mL of at least one species of bacteria B. subtilis; a.2) from about 0.1% to about 5% w/w of a material containing keratin fibers; a.3) from about 0.005% to about 10% w/w of culture medium; where the pH of the medium is within a range from 7.5 to 8.5; b) keeping the mixture a) in a temperature within a range from 20° C. to 35° C. under agitation to obtain a supernatant; c) separating the supernatant obtained in b); d) separating hydrolysated peptides of supernatant of stage c). 2. The process of claim 1, wherein said bacterium is B. subtilis strain AMR. 3. The process of claim 1, characterized by further using a concentration of 107 cells/mL of bacteria in step a.1). 4. The process of claim 1, wherein the material containing keratin fibers is selected from the group consisting of hair, feathers, hooves, nails, horns and combinations thereof. 5. The process of claim 4, wherein the feathers are chosen from the group consisting of chicken, hen, ducks, geese feathers and combinations thereof. 6. The process of claim 1, wherein the material containing keratin fibers are at a concentration of 1% w/w. 7. The process of claim 1, wherein the culture medium comprises yeast extract, peptone, KCl, sucrose or combinations thereof. 8. The process of claim 1, wherein the growth medium is at a concentration of 5% w/w. 9. The process of claim 1, wherein the process is conducted at pH 8.0. 10. The process of claim 1, wherein the process is conducted at 28° C. 11. The process of claim 1, wherein the process is conducted at an agitation of 300 rpm. 12. Process, according to claim 1, characterized by separation mentioned in c) being held by centrifugation. 13. The process of claim 1, wherein the separation mentioned in d) is conducted by ultrafiltration. 14. The process of claim 1, characterized by comprising an additional step of preparation of the material containing keratin fibers, before using it in the step a). 15. The process of claim 14, characterized by comprising at least one additional step selected from the group consisting of: A) washing; B) drying; C) delipidation, and D) combinations of a), b) and/or c). 16. The process of claim 15, characterized by the fact that the step of washing is conducted with the aid of a detergent. 17. The process of claim 15, wherein the step of delipidation comprises the use of a chloroform:methanol mixture at a ratio from 0.5:1 up to 3:1. 18. Keratin hydrolysates characterized by having a molecular weight within a range from 500 Da to 1000 Da. 19. Keratin hydrolysates, according to claim 18, characterized by being obtained with the process of claim 1. 20. Cosmetics composition characterized by comprising: a) from 0.0001% w/w to 20% w/w of a keratin hydrolysate having a molecular weight within a range from 500 Da to 1000 Da; and b) an appropriate cosmetic vehicle. 21. The cosmetics composition, of claim 20, characterized by comprising 10% w/w of a keratin hydrolysate. 22. The cosmetics composition, of claim 20, characterized by being formulated for use in hair, skin and/or nails. 23. The cosmetics composition, of claim 22, wherein the composition is in the form of a shampoo and/or conditioner. 24. The cosmetics composition, of claim 20, characterized being formulated for use in the treatment of capillary fiber.
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