초록 ▼

A photo ionization detector (PID) is provided for selectively determining various compounds or gases present in a breath sample. The PID, comprises a substrate comprising a gas ionization chamber, at least one pair of ion sensing electrodes, and at least one amplifying circuit; and an ultraviolet (U

A photo ionization detector (PID) is provided for selectively determining various compounds or gases present in a breath sample. The PID, comprises a substrate comprising a gas ionization chamber, at least one pair of ion sensing electrodes, and at least one amplifying circuit; and an ultraviolet (UV) ionization source to transmit a UV light beam into the gas ionization chamber. A system comprises the PID is also provided. A method of detecting a response pattern for various compounds or gases in breath using PID is also provided.

대표청구항 ▼

1. A photo-ionization detector (PID), comprising: a substrate comprising a gas ionization chamber,at least one pair of ion sensing electrodes,and at least one amplifying circuit; andat least one ultraviolet (UV) ionization source to transmit a UV light beam into the gas ionization chamber in the sub

1. A photo-ionization detector (PID), comprising: a substrate comprising a gas ionization chamber,at least one pair of ion sensing electrodes,and at least one amplifying circuit; andat least one ultraviolet (UV) ionization source to transmit a UV light beam into the gas ionization chamber in the substrate. 2. The photo-ionization detector of claim 1, wherein the substrate further comprises a heating element. 3. The photo-ionization detector of claim 1, wherein the substrate further comprises a temperature sensor. 4. The photo-ionization detector of claim 1, wherein the substrate further comprises a temperature feedback control circuit. 5. The photo-ionization detector of claim 1, wherein the substrate is made of one or more conducting layers, dielectric layers, or combinations of conducting layers and dielectric layers. 6. The photo-ionization detector of claim 1, wherein the substrate is a printed circuit board. 7. The photo-ionization detector of claim 1, wherein the substrate comprises an array of holes or open slots. 8. The photo-ionization detector of claim 1, wherein the detector comprises a plurality of UV sources. 9. The photo-ionization detector of claim 1, wherein the ultraviolet (UV) ionization source is an ultraviolet lamp (UV lamp), or a light emitting diode (LED). 10. The photo-ionization detector of claim 1, wherein the UV light beam is directed into the gas ionization chamber perpendicular to the substrate. 11. The photo-ionization detector of claim 1, wherein the at least one amplifying circuit and the at least one pair of ion sensing electrodes incorporates an electrical guard ring to reduce leakage current signal. 12. The photo-ionization detector of claim 1, wherein the at least one amplifying circuit is selected from a transimpedance amplifying circuit, or current-to-current amplifying circuit. 13. The photo-ionization detector of claim 1, further comprising a direct current (DC) voltage source. 14. The photo-ionization detector of claim 1, further comprising a diffuser that regulates a gas flow into the gas ionization chamber. 15. A photo-ionization detector (PID), comprising: a substrate comprising a gas ionization chamber,at least one pair of ion sensing electrodes,and a heating element;an ultraviolet (UV) ionization source to transmit a UV light beam into the gas ionization chamber. 16. The photo-ionization detector of claim 15 further comprises a temperature sensor, and a temperature feedback control circuit in operative association with the substrate. 17. The photo-ionization detector of claim 15 is configured to detect aliphatic hydrocarbons, aromatic hydrocarbons, aldehydes, ketones, or alcohols. 18. The photo-ionization detector of claim 15 is configured to detect acetone, isoprene, ammonia, or benzene. 19. The photo-ionization detector of claim 15 is configured to detect acetone. 20. The photo-ionization detector of claim 15, wherein the ultraviolet (UV) ionization source is directly fixed on the lamp driver board. 21. The photo-ionization detector of claim 15, wherein the ultraviolet (UV) ionization source transmits ultraviolet (UV) light in a frequency range from about 100 nm to 210 nm. 22. A system comprising the photo-ionization detector of claim 15. 23. A system for measuring a compound in a gas mixture, comprising: a photo-ionization detector (PID) and a pressure sensor,wherein the PID comprises at least one ultraviolet (UV) ionization source and a substrate comprising a gas ionization chamber, at least one pair of ion sensing electrodes, and at least one amplifying circuit. 24. The system of claim 23, further comprising a processor configured to produce a sensor response pattern that indicates an amount of the compound in the gas mixture. 25. The system of claim 23, further comprising a diffuser that regulates a flow of the gas mixture. 26. The system of claim 25, wherein the diffuser is coupled to the gas ionization chamber. 27. The system of claim 23, wherein the at least one pair of ion sensing electrodes is an acetone sensing electrodes. 28. The system of claim 23, wherein the ultraviolet (UV) ionization source is directly fixed to the substrate. 29. The system of claim 23, wherein the ultraviolet (UV) ionization source is an UV lamp of 8.4 eV, 9.6 eV, 9.8 eV, 10 eV, 10.2 eV, 10.6 eV or 11.6 eV. 30. The system of claim 23, further comprising a gas flow-rate sensor. 31. The system of claim 23, further comprising a CO2 sensor. 32. The system of claim 23, further comprising a controller in operative association with the substrate. 33. A method of measuring a compound in a breath sample by a photo-ionization detector (PID), comprising: introducing the breath sample into the photo-ionization detector,transmitting an ultraviolet (UV) light beam through the breath sample;ionizing the breath sample; anddetecting an amount of the compound in the breath sample. 34. The method of claim 33, wherein the compound is selected from acetone, isoprene, ethanol, methanol, ammonia, ethane, or pentane. 35. The method of claim 33, wherein the step of introducing the breath sample comprises pre-concentrating one or more selected compounds of the breath sample. 36. The method of claim 33, wherein the step of introducing the breath sample comprises filtering one or more selected compounds of the breath sample. 37. The method of claim 33, wherein the compound is acetone. 38. The method of claim 33, further generating a sensor response pattern. 39. The method of claim 38, wherein the sensor response pattern quantifies the amount of the compound present in the breath sample. 40. The method of claim 33, further comprising heating the photo-ionization detector by using a heating element for maintaining a temperature inside the photo-ionization detector. 41. The method of claim 33, further comprising measuring a temperature of the photo-ionization detector by a temperature sensor present in the photo-ionization detector. 42. The method of claim 33, further controlling a temperature-feedback control mechanism using the temperature sensor and the heating element.