초록 ▼

The present invention provides dietary formulations comprising polyunsaturated fatty acids and vitamin E. The present invention further provides methods of treating various conditions, generally involving administering to an individual in need thereof an effective amount of a subject dietary formula

The present invention provides dietary formulations comprising polyunsaturated fatty acids and vitamin E. The present invention further provides methods of treating various conditions, generally involving administering to an individual in need thereof an effective amount of a subject dietary formulation.

대표청구항 ▼

1. A dietary formulation comprising: a) eicosapentaenoic acid (EPA);b) docosohexaenoic acid (DHA);c) α-tocopherol; andd) γ-tocopherol, wherein the ratio of EPA to DHA is in a range of from about 1.5:1 to about 5:1. 2. The formulation of claim 1, wherein the α-tocopherol is present in an amount of fr

1. A dietary formulation comprising: a) eicosapentaenoic acid (EPA);b) docosohexaenoic acid (DHA);c) α-tocopherol; andd) γ-tocopherol, wherein the ratio of EPA to DHA is in a range of from about 1.5:1 to about 5:1. 2. The formulation of claim 1, wherein the α-tocopherol is present in an amount of from about 500 mg to about 3000 mg per unit dose, and the γ-tocopherol is present in an amount of from about 200 mg to about 1000 mg per unit dose. 3. The formulation of claim 1, further comprising α-lipoic acid in an amount of from about 50 mg to about 600 mg per unit dose. 4. The formulation of claim 1, further comprising carnitine in an amount of from about 200 mg to about 3000 mg per unit dose. 5. The formulation of claim 1, further comprising an omega-6 fatty acid. 6. The formulation of claim 5, wherein the omega-6 fatty acid is γ-linolenic acid. 7. The formulation of claim 1, further comprising an omega-9 fatty acid. 8. The formulation of claim 7, wherein the omega-9 fatty acid is oleic acid. 9. The formulation of claim 1, further comprising vitamin C in an amount of from about 200 mg to about 500 mg. 10. The formulation of claim 1, further comprising vitamin K. 11. The formulation of claim 1, further comprising phosphocholine. 12. The formulation of claim 1, further comprising zinc. 13. The formulation of claim 1, further comprising one or more additional components selected from coenzyme Q, selenium, vitamin A, vitamin B1, riboflavin, vitamin B6, vitamin B12, vitamin D, arginine, calcium, magnesium, vitamin B7, vitamin B9, vitamin B5, tetrahydrobiopterin, and vitamin B3. 14. The formulation of claim 1, further comprising a pancreatic enzyme. 15. The formulation of claim 1, further comprising a leukotriene inhibitor. 16. The formulation of claim 1, wherein the formulation is in a dosage form selected from a tablet, a capsule, a powder, a gel, and a liquid. 17. The formulation of claim 1, further comprising one or more food-grade components. 18. A method of treating apraxia and/or autism spectrum disorder, the method comprising orally administering to an individual in need thereof an effective amount of the formulation of claim 1. 19. The method of claim 18, wherein the formulation is administered three times daily. 20. The method of claim 18, wherein the formulation is administered twice daily. 21. The method of claim 18, wherein the formulation is administered once daily. 22. The method of claim 18, wherein said administration is effective to increase the percentile score of at least one of oral movement score, simple phonemic/syllabic score, complex phonemic/syllabic score, and spontaneous length and complexity score, by at least about 10 percentile points. 23. A method of treating an allergic disorder, the method comprising orally administering to an individual in need thereof an effective amount of the formulation of claim 1. 24. The method of claim 23, wherein the disorder is selected from celiac disease, sprue, gluten sensitivity, a malabsorption syndrome, asthma, food allergy, leaky gut syndrome, and/or eczema. 25. A method of treating an inflammatory condition, the method comprising orally administering to an individual in need thereof an effective amount of the formulation of claim 1, wherein the inflammatory condition is rheumatic arthritis, diabetes, or cardiovascular disease.