[특허]Coating composition and therapeutic preparation incorporating same

[미국특허] Coating composition and therapeutic preparation incorporating same 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-009/22
출원번호	US-0473289 (1974-05-24)
발명자 / 주소	Pescetti Anthony (999 E. Mission Road Fallbrook CA 92028)
인용정보	피인용 횟수 : 18 인용 특허 : 0

초록 ▼

A therapeutic preparation consisting of particles containing a therapeutically active material are coated with a disintegratable coating comprising zein and shellac. A first group of particles contains no coating or a coating subject to rapid disintegration upon ingestion to release an initial dose of therapeutic material and remaining groups of particles are coated with increasingly thicker coatings for delayed disintegration to release subsequent doses of therapeutic material. The coating composition may include disintegration modifiers so that thinner coatings of the zein-shellac coating material can be employed than would be required for zein shellac alone to obtain the delayed disintegration of the coating.

대표청구항 ▼

A therapeutic preparation comprising a pharmaceutical gelatin capsule containing a blend of three groups of particles containing a pharmaceutically active material, said first group containing a unit dose amount of said material for release thereof within a period of one hour after ingestion, a second group of said particles containing a unit dose amount of said material being provided with a coating comprising a major proportion of zein and shellac in a weight/weight ratio of between 1:7 and about 1:14 and minor proportions of ethyl cullulose, bees wax and a plasticizer, said coating having an effective thickness for disintegration and relase of said material in a period of about 4 hours after ingestion, and a third group of said particles containing a unit dose amount of said material being provided with a coating comprising a major proportion of zein and shellac in a weight/weight ratio of between about 1:7 and about 1:14 and minor proportions of ethyl cellulose, bees wax, polyvinylpyrrolidone and a plasticizer, said coating having an effective thickness for disintegration and relase of said material in about a period of about 8 hours after ingestion.

이 특허를 인용한 특허 (18) 인용/피인용 타임라인 분석

Beland, Rene Maurice; Helf, Thomas A.; Kimball, James F.; Paas, Edward L., Actuator cap for a spray device.
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Heim, Stefan; Schmid, Martina Birgit; Theurer, Christoph Walter, Composition.
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Venkatesh, Gopi; Kramer, Craig, Controlled release potassium chloride tablets.
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Powell Thomas Clark (West Alexandria OH), Controlled release potassium tablet.
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Potthoff, Klaus, Diagnostic method and diagnostic means used in delivering a medicament to a patient.
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Shaffer Richard D. (Lawrence KS) Windheuser John J. (Lawrence KS), Enteric coated digoxin and therapeutic use thereof.
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Beatty Morgan L. (Waterford CT) Boettner Wayne A. (Mystic CT), Long-acting matrix tablet formulations.
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Komorowski, James R., Methods and compositions for sustained release of chromium.
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Komorowski, James R., Methods and compositions for the sustained release of chromium.
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Komorowski, James R., Methods and compositions for the sustained release of chromium.
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George, Eapen; Given, Jr., Peter S; Grover, Julie Anne; Guardiola, Lia; Padua, Graciela Wild, Methods of flavor encapsulation and matrix-assisted concentration of aqueous foods and products produced therefrom.
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Komorowski, James R, Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement.
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Komorowski, James R., Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement.
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Komorowski, James R., Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement.
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Meyer Glenn A. (Waukegan IL) Mazer Terrence B. (Reynoldsburg OH), Prolamine coatings for taste masking.
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Bernstein Howard (Cambridge MA) Morrel Eric (Needham MA) Mathiowitz Edith (Brookline MA) Schwaller Kirsten (Duxbury MA) Beck Thomas R. (Concord MA), Protein microspheres and methods of using them.
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Moest Thomas (Moorrege DEX), Solid pharmaceutical sustained-release form.
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Block,Juergen; Heim,Stefan; Westerheide,Ralf, Sustained release vitamin composition.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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[미국특허] Coating composition and therapeutic preparation incorporating same 원문보기