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특허 상세정보

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Electrophoretic method of detecting antigen-antibody reaction

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) G01N-027/26    G01N-033/16   
미국특허분류(USC) 424/12 ; 23/230B ; 23/253R ; 204/150R
출원번호 US-0631727 (1975-11-13)
발명자 / 주소
  • Uzgiris Egidijus E. (Schenectady NY)
출원인 / 주소
  • General Electric Company (Schenectady NY 02)
인용정보 피인용 횟수 : 244  인용 특허 : 0
초록
▼

A method of rapidly detecting presence of antibodies in a solution comprises depositing, on each of a plurality of microscopic particles, an antigen specific to the antibodies sought, and forming a dilute suspension of the particles in the solution to be examined. The suspension is stirred, and electrophoretic mobility of the particles is measured upon formation of the suspension and measured again at a subsequent time. Detection of a change in electrophoretic mobility of the particles between the two measurements indicates presence of the antibodies in ...

대표
청구항

The method of detecting an antigen-antibody reaction comprising the steps of: depositing an antigen on each of a plurality of microscopic particles; forming a dilute suspension of said particles in a solution to be tested for presence of antibodies specific to the antigens on said particles; stirring said suspension; and comparing electrophoretic mobilities of said particles aT two different times.

이 특허를 인용한 특허 (244)

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  153. Idelevich, Pavel; Elkeles, Adi; Terkieltaub, Dov; Eyal, Ami; Gelvan, Dan Jacob, Methods and kits for differential staining of abnormal urinary system cells.
  154. Altschuler, Yoram; Tarcic, Gabi, Methods and systems for identifying patient specific driver mutations.
  155. Chaparian, Michael G.; Azad, Abul, Methods and targets of antibiotic resistance.
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  164. Peled, Tony; Fibach, Eitan; Treves, Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
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  166. Peled, Tony; Steinhardt, Yair, Methods of culturing and expanding mesenchymal stem cells.
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  189. Hochberg, Avraham, Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer.
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  193. Fima, Udi Eyal; Hershkovitz, Oren, Pegylated OXM variants.
  194. Fima, Udi Eyal; Hershkovitz, Oren, Pegylated OXM variants.
  195. Richard Y. Liu ; Kenneth S. Zuckerman, Peptide antagonists of tumor necrosis factor alpha.
  196. Yemini, Miri; Reches, Meital; Rishpon, Judith; Gazit, Ehud, Peptide nanostructure-coated electrodes.
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  205. Gazit, Ehud, Peptides and methods using same for diagnosis and treatment of amyloid-associated disease.
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  210. Stein,Hanan; Zilberstein,Aviah; Miller,Gadi; Kapulnik,Yoram, Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby.
  211. Harats, Dror; Greenberger, Shoshana; Breitbart, Eyal, Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy.
  212. Sammons, Robert D; Ivashuta, Sergey; Liu, Hong; Wang, Dafu; Feng, Paul C. C.; Kouranov, Andrei Y; Andersen, Scott E, Polynucleotide molecules for gene regulation in plants.
  213. Ayal, Sharon; Karchi, Hagai; Gold, Evgenia; Bekerman, Laura, Polynucleotides and polypeptides involved in plant fiber development and methods of using same.
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  228. Kollet, Orit; Lapidot, Tsvee, Stem cells having increased sensitivity to SDF-1 and methods of generating and using same.
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