초록 ▼

An ocular drug dispensing device for administering a drug at a controlled and continuous dosage unit rate to the eye to produce a local or systemic physiological or pharmacological effect is comprised of a shaped body insoluble in tear fluid and comprised of a first wall, a third wall distant from t

An ocular drug dispensing device for administering a drug at a controlled and continuous dosage unit rate to the eye to produce a local or systemic physiological or pharmacological effect is comprised of a shaped body insoluble in tear fluid and comprised of a first wall, a third wall distant from the first wall, a second wall interposed between the first and third wall and extending around their peripheries for sealingly engaging the first and third wall, a reservoir defined by the inner surfaces of the walls and containing the drug or a mixture of the drug in a carrier and wherein at least one of the first and third walls is formed of an imperforate drug release rate controlling material permeable to the passage of drug or a microporous material containing in the micropores a drug release rate controlling medium permeable to the passage of drug for administering a therapeutically effective amount of drug over a prolonged period of time.

대표청구항 ▼

An ocular device for the administration of drug comprising a three layered laminate having a pair of separate and discrete first and third walls formed of a material insoluble in tear fluid with one of the walls formed of a drug release rate controlling material permeable to the passage of drug and

An ocular device for the administration of drug comprising a three layered laminate having a pair of separate and discrete first and third walls formed of a material insoluble in tear fluid with one of the walls formed of a drug release rate controlling material permeable to the passage of drug and the other wall formed of a material impermeable to the passage of drug, a second wall interposed between the first and third walls and formed with an inwardly disposed hole with the second wall sealingly engaging the first and third walls to form a reservoir Containing a drug selected from the group consisting of antibiotic, antibacterial, antiviral, antiallergenic, anti-inflammatory, miotic, anticholinesterase, mydriatic and sympathomimetic drugs, and wherein drug is administered from the device at a controlled and continuous rate by passage through the rate controlling wall over a prolonged period of time.