초록 ▼

A light-sensitive and oxygen-sensitive liquid such as an adrenalin solution for ophthalmic use is sealed within a polymer vessel provided with a dropper spout, the closed vessel itself being sealed within a light-tight gas-impermeable envelope which is purged with a non-reactive gas or is under vacu

A light-sensitive and oxygen-sensitive liquid such as an adrenalin solution for ophthalmic use is sealed within a polymer vessel provided with a dropper spout, the closed vessel itself being sealed within a light-tight gas-impermeable envelope which is purged with a non-reactive gas or is under vacuum. The envelope is preferably a three-component laminate of nylon aluminum foil and polypropylene.

대표청구항 ▼

A packaged medicant comprising (1) an outer hermetically sealed envelope, (2) an inner dispenser bottle, and (3) an inert atmosphere within the envelope within which the dispenser bottle is immersed; said hermetically sealed envelope comprising a three-ply laminate wherein the outer ply is an abrasi

A packaged medicant comprising (1) an outer hermetically sealed envelope, (2) an inner dispenser bottle, and (3) an inert atmosphere within the envelope within which the dispenser bottle is immersed; said hermetically sealed envelope comprising a three-ply laminate wherein the outer ply is an abrasive-resistant polymer, an intermediate ply which is aluminum foil, and an inner ply which is a heat-sealable polymer, said three-ply laminate in combination excluding entry of oxygen and light and preventing escape of water vapor and the inert atmosphere; said inert atmosphere within the envelope being oxygen; free; and said dispensing bottle being a translucent polymer and containing a solution of light-sensitive, oxygensensitive medicAnt and an anti-oxident and comprising a receptacle for holding a predetermined quantity of the liquid medicant provided with a neck defining an opening to the interior of the receptacle, a discharge element comprising a cylindrical part press-fitted into the opening in the neck, a tapered nozzle through which the liquid medicant in the receptacle is adapted to be dispensed in predetermined doses, and an annular, externally-located collar in conjunction with the cylindrical part and the tapered nozzle for seating of the discharge element within the neck, said tapered nozzle terminating in an end opening of a diameter to dispense said predetermined dose and said receptacle having elastically flexible walls such as to enable squeezing the walls to displace a dose through the opening at the end of said tapered nozzle, a closure cap arranged to be releasably applied to the neck over the tapered nozzle and a sealing element interiorly of the cap arranged to become engaged with the opening at the end of the nozzle when the cap is applied to the neck to provide a leaktight barrier between the opening and the interior of the cap.