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Magnetic particles for immunoassay 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/00
출원번호 US-0813422 (1977-07-06)
우선권정보 GB-0031839 (1976-07-30)
발명자 / 주소
  • Davies George E. (Macclesfield UT GB2) Janata Jiri (Salt Lake City UT)
출원인 / 주소
  • Imperial Chemical Industries Limited (GBX 03)
인용정보 피인용 횟수 : 74  인용 특허 : 2

초록

This invention relates to magnetic particles and to the use thereof. Each particle comprises a low density core and a component therewith, at least a portion of the surface of the core being coated with magnetic material.

대표청구항

Composite magnetic particles each particle comprising a core having a density of less than 1.5 gm/cc, at least a proportion of the surface of the core being coated with a coating of magnetic material and a biologically active component on the surface of the core and/or the said coating.

이 특허에 인용된 특허 (2)

  1. Roberts Roy (Lindfield AU), Chemically reactive resin beads and to methods of their manufacture.
  2. Gable Howard S. (Kansas City KS) Kerr Glenn W. (Mission KS), Magnetic organo-iron compounds.

이 특허를 인용한 특허 (74)

  1. Elings, Virgil B.; Nicoli, David F., Apparatus and method for homogeneous immunoassay.
  2. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; Adamson, Douglas H., Apparatus having polymer surfaces having a siloxane functional group.
  3. Gribnau Thomas C. J. (Haren NLX) Roeles Frits (Dreumel NLX) Leuvering Johannes H. W. (Heesch NLX), Application of water-dispersible hydrophobic dyes or pigments as labels in immunoassays.
  4. Chandler Howard M.,CAX, Assay device.
  5. Kamada Satoru (Yamato JPX) Iwasaki Shuji (Machida JPX), Assay method and apparatus of immune reaction.
  6. Nova Michael P. ; Lillig John E. ; Karunaratne Kanchana Sanjaya Gunesekera ; Ewing William ; Satoda Yozo ; Potash Hanan, Automated sorting system for matrices with memory.
  7. Chagnon Mark S. (Lowell MA) Groman Ernest V. (Brookline MA) Josephson Lee (Arlington MA) Whitehead Roy A. (Hingham MA), Binding assays employing magnetic particles.
  8. Browne, Douglas; Straus, Don; Mace, Chad, Cassette containing growth medium.
  9. Aviles, Robert C.; Michaud, Devin T.; Browne, Douglas J., Cassette for sterility testing.
  10. Mirkin, Chad A.; Chen, Xiaodong; Xue, Can; Hurst, Sarah J., Coated colloidal materials.
  11. Czerlinski George H. (9111 Forest View Rd. Evanston IL 60203), Coated magnetizable microparticles, reversible suspensions thereof, and processes relating thereto.
  12. Mitani Katsuo (Fujisawa JPX) Une Hiroshi (Fujisawa JPX), Dyed inorganic composite particles and process for production thereof.
  13. Mandecki, Wlodek, Electronically-indexed solid-phase assay for biomolecules.
  14. Wlodek Mandecki, Electronically-indexed solid-phase assay for biomolecules.
  15. Andres,Ronald P.; Ng,Alicia T., Fe/Au nanoparticles and methods.
  16. Henderson Timothy M. (Ann Arbor MI), Glass-surface microcarrier for growth of cell cultures.
  17. Adams, Thomas; Jablonski, Edward, Homogeneous analyte detection.
  18. Adams, Thomas; Jablonski, Edward, Homogeneous analyte detection.
  19. Okada, Masahisa; Ashihara, Yoshihiro; Yano, Akira; Oishi, Masao; Yoshioka, Katsuaki; Nakamura, Toshiomi, Immunoassay using magnetic particle.
  20. Chandler Howard M. ; Piasio Roger N. ; Prouty Karen, Immunochromatographic assay device.
  21. Yamauchi Syoichi,JPX ; Kasai Kiyoshi,JPX, Magnetic carrier, preparation thereof, and method of extraction of nucleic acid.
  22. Yamauchi, Syoichi; Kasai, Kiyoshi, Magnetic carrier, preparation thereof, and method of extraction of nucleic acid.
  23. Molday Robert S. (Vancouver CAX), Magnetic iron-dextran microspheres.
  24. Sasaki Motohiro,JPX ; Matsukawa Masahiko,JPX ; Yoshioka Katsuaki,JPX ; Anan Makoto,JPX ; Isomura Mitsuo,JPX ; Ashihara Yoshihiro,JPX ; Okada Masahisa,JPX, Magnetic particle and immunoassay using the same.
  25. Benner Steven A. (Cambridge MA), Magnetic particles as supports for organic synthesis.
  26. Chagnon Mark S. (Lowell MA) Groman Ernest V. (Brookline MA) Josephson Lee (Arlington MA) Whitehead Roy A. (Hingham MA), Magnetic particles for use in separations.
  27. Josephson Lee (Arlington MA), Magnetic particles for use in separations.
  28. Whitehead Roy A. (Hingham MA) Chagnon Mark S. (Lowell MA) Groman Ernest V. (Brookline MA) Josephson Lee (Arlington MA), Magnetic particles for use in separations.
  29. DeFilippi Louis J. (Mount Prospect IL), Magnetic support matrix for enzyme immobilization.
  30. Winstead, J; Grimm, William L., Magnetically-responsive microparticles with improved response times.
  31. Nova Michael P. ; Parandoosh Zahra ; Senyei Andrew E. ; Xiao Xiao-Yi ; David Gary S. ; Satoda Yozo ; Zhao Chanfeng ; Potash Hanan, Matrices with memories and uses thereof.
  32. Nova Michael P. ; Lillig John E. ; Karunaratne Kanchana Sanjaya Gunesekera ; O'Neil Donald ; Ewing William ; Satoda Yozo, Matrices with memories in automated drug discovery and units therefor.
  33. Leuvering Johannes H. W. (Heesch NLX), Metal sol particle immunoassay.
  34. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; O'keefe, Christian V.; Adamson, Douglas H., Method and system for releasing mineral from synthetic bubbles and beads.
  35. Abrams, Ezra; Gite, Sadanand; Shinefeld, Lisa; Straus, Don; Siek, Gordon; Yantz, Greg, Method for detecting analytes.
  36. Arnquist David C. ; Barnes ; III Grady ; Button Richard D. ; Dunn Chadwick M. ; East ; Jr. Richard C. ; Fritchie Patrick P. ; Galitz Charles M. ; Gardner Gregory E. ; Grandone Cass J. ; Gray Robert C, Method for determination of item of interest in a sample.
  37. Mandecki Wlodek, Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders.
  38. Mandecki Wlodek, Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders.
  39. Arnquist David C. ; Barnes ; III Grady ; Dunn Chadwick M. ; East ; Jr. Richard C. ; Fritchie Patrick P. ; Gardner Gregory E. ; Grandone Cass J. ; Gray Robert C. ; Holen James T. ; McCoy Jimmy D. ; Mi, Method of performing a process for determining an item of interest in a sample.
  40. Wang Chia-Gee (Millwood NY), Method of tagged immunoassay.
  41. Dong, Xing; Paris, Henry, Method to remove agent from liquid phase.
  42. Wang Chaeo-Huej J. ; Shah Dinesh O., Method to use fluorescent magnetic polymer particles as markers in an immunoassay.
  43. Jablonski, Edward; Adams, Thomas, Microbubbles for affinity separation.
  44. Jablonski, Edward; Adams, Thomas, Microbubbles for affinity separation.
  45. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; O'Keefe, Christian V.; Kersey, Alan D.; Adamson, Douglas H., Mineral recovery in tailings using functionalized polymers.
  46. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; Adamson, Douglas H., Mineral separation using functionalized filters and membranes.
  47. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; O'Keefe, Christian V.; Kersey, Alan D.; Adamson, Douglas H., Mineral separation using sized-, weight- or magnetic-based polymer bubbles or beads.
  48. Chandler Howard M.,CAX, Multiple component chromatographic assay device.
  49. Mandecki Wlodek, Multiplex assay for nucleic acids employing transponders.
  50. Mandecki Wlodek, Multiplex assay for nucleic acids employing transponders.
  51. Wlodek Mandecki, Multiplex assay for nucleic acids employing transponders.
  52. Chandler, Van S.; Fulton, R. Jerrold; Chandler, Mark B., Multiplexed analysis of clinical specimens apparatus and method.
  53. Chandler, Van S.; Fulton, R. Jerrold; Chandler, Mark B., Multiplexed analysis of clinical specimens apparatus and method.
  54. Van S. Chandler ; Jerrold R. Fulton ; Mark B. Chandler, Multiplexed analysis of clinical specimens apparatus and method.
  55. Chandler, Don J.; Chandler, Van S., Multiplexed analysis of clinical specimens apparatus and methods.
  56. Kakimi Fujio (Minami-ashigara JPX) Hiratsuka Nobuo (Tokyo JPX) Matsukawa Hiroharu (Shizuokashi JPX), Novel material for immunological assay of biochemical components and a process for the determination of said components.
  57. Chandler Howard M.,CAX, Opposable-element assay devices, kits, and methods employing them.
  58. Hudson Derek (52 El Cerrito Ave. San Anselmo CA 94960) Cook Ronald M. (7 Meadow La. Novato CA 94947), Oxidized polyethylene or polypropylene particulate supports.
  59. Straus, Don, Rapid and sensitive detection of cells and viruses.
  60. Straus, Don, Rapid and sensitive detection of molecules.
  61. Straus, Don, Rapid detection of replicating cells.
  62. Straus, Don, Rapid detection of replicating cells.
  63. Nova Michael P. ; Senyei Andrew E. ; David Gary S., Remotely programmable matrices with memories.
  64. Wlodek Mandecki, Screening of drugs from chemical combinatorial libraries employing transponders.
  65. Mandecki Wlodek, Screening of soluble chemical compounds for their pharmacological properties utilizing transponders.
  66. Mansfield Gerald R. (Painted Post NY) Travis Karen L. (Corning NY) Vann William P. (Beaver Dams NY), Solid-phase immunoassays using magnetic glass.
  67. Arnquist, David C.; Barnes, III, Grady; Button, Richard D.; Dunn, Chadwick M.; East, Jr., Richard C.; Fritchie, Patrick P.; Galitz, Charles M.; Gardner, Gregory E.; Grandone, Cass J.; Gray, Robert C., Structure for determination of item of interest in a sample.
  68. Elaissari Abdelhamid,FRX ; Pichot Christian,FRX ; Mandrand Bernard,FRX ; Sauzedde Florence,FRX, Superparamagnetic monodisperse particles.
  69. Pilgrimm Herbert,DEX, Superparamagnetic particles, process for producing the same and their use.
  70. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; O'Keefe, Christian V.; Kersey, Alan D.; Adamson, Douglas H., Synthetic beads/bubbles functionalized with molecules for attracting and attaching to mineral particles of interest.
  71. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; O'Keefe, Christian V.; Kersey, Alan D.; Adamson, Douglas H., Synthetic bubbles or beads having hydrophobic surface.
  72. Wang Chia-Gee (Millwood NY), Tagged immunoassay.
  73. Rothman, Paul J.; Fernald, Mark R.; Didden, Francis K.; Adamson, Douglas H., Techniques for transporting synthetic beads or bubbles in a flotation cell or column.
  74. Dean ; Jr. Robert C. (Norwich VT) Silver Frederick H. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Phillips Philip G. (Norwich VT) Runstadler ; Jr. Peter W. (Hanover NH), Weighted collagen microsponge for immobilizing bioactive material.
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