초록 ▼

A hemoperfusion adsorbent is provided comprising a woven or knitted fibrous carbon adsorbent material having at least one coating thereon of a hydrophilic polymer. The adsorbent carbon fabric is preferably derived from a novolak-type phenolic resin. The hydrophilic polymer will preferably comprise a

A hemoperfusion adsorbent is provided comprising a woven or knitted fibrous carbon adsorbent material having at least one coating thereon of a hydrophilic polymer. The adsorbent carbon fabric is preferably derived from a novolak-type phenolic resin. The hydrophilic polymer will preferably comprise a polymer prepared by the polymerization of at least one monomeric acrylate or methacrylate, preferably with a copolymerizable monomer containing an epoxy moiety.

대표청구항 ▼

An adsorbent for hemoperfusion which comprises a woven or knitted fibrous structure of activated carbon with a bulk density of at least 0.25 g/cc, said activated carbon having been derived from a fibrous precursor selected from the group consisting of regenerated cellulose, polyacrylonitrile and a t

An adsorbent for hemoperfusion which comprises a woven or knitted fibrous structure of activated carbon with a bulk density of at least 0.25 g/cc, said activated carbon having been derived from a fibrous precursor selected from the group consisting of regenerated cellulose, polyacrylonitrile and a thermosetting polymer, and having at least one coating thereon of a hydrophilic, blood-compatible, film-forming copolymer prepared by polymerization of at least one monomeric acrylate or methacrylate represented by the formula: [Figure] wherein R1 is hydrogen or methyl; and Y is a radical selected from the group consisting of －R2－OR3 and －R2－NR3R3′, wherein R2 is a divalent alkylene radical containing 2 to 3 carbon atoms or a poly (oxyalkylene) radical, and R3 and R3′, respectively, are hydrogen or an alkyl group containing 1 to 3 carbon atoms, with a copolymerizable monomer containing an epoxy radical therein represented by the formula: [Figure] wherein each of R1, R1′, and R1″independently is hydrogen or methyl; Z is a divalent radical selected from the group consisting of －COOR2 and －CH2－OCH2－, wherein R2 is a divalent alkylene radical containing 1 to 3 carbon atoms or a poly(oxyalkylene) radical; and n is 0 or 1; the copolymerizable monomer being present therein in the range of from 0.1 to 10% based on the weight of total monomers.