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특허 상세정보

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Method and preparation for administration to the mucosa of the oral or nasal cavity

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-031/74    A61K-031/78   
미국특허분류(USC) 424/14 ; 106/35 ; 128/260 ; 424/16
출원번호 US-0103558 (1979-12-13)
발명자 / 주소
  • Nagai Tsuneji (Chofu JPX) Machida Yoshiharu (Kawasaki JPX) Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX)
출원인 / 주소
  • Teijin Limited (JPX 03)
인용정보 피인용 횟수 : 89  인용 특허 : 1
초록
▼

A method for administering a medicament which comprises adhering to the mucosa of the oral or nasal cavity a pharmaceutical preparation comprising (a) a water-swellable and mucosa-adhesive polymeric matrix comprising about 50 to about 95% by weight of a cellulose ether and about 50 to about 5% by weight of a homo- or copolymer of acrylic acid or a pharmaceutically acceptable salt thereof, and (b) dispersed therein, a pharmaceutically effective amount of the medicament, said preparation releasing continuously the medicament at a controlled rate; and causi...

대표
청구항
▼

In a method for administering a medicament which comprises adhering with a polyacrylate to the mucosa of the oral cavity a pharmaceutical preparation, the improvement comprising adhering said medicament with (a) a water-swellable and mucosa-adhesive polymeric matrix comprising about 50 to about 95% by weight of a cellulose ether and about 50 to about 5% by weight of a homo- or copolymer of acrylic acid or pharmaceutically acceptable salt thereof, and (b) dispersed therein, a pharmaceutically effective amount of the medicament to be adhered to the oral mu...

이 특허에 인용된 특허 (1)

  1. Tanaka Wataru (Hoya JA) Akito Eiichiro (Omiya JA) Yoshida Koichi (Soka JA) Terada Takashi (Yono JA) Ninomiya Hiroshi (Sayama JA), Pharmaceutical preparation for oral cavity administration.

이 특허를 인용한 특허 (89)

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  39. Bomberger,David C.; Catz,Paul G.; Smedley,Mark I.; Stearns,Paul C., ICAM-1 formulation having controlled-size microparticles.
  40. Jernberg Gary R. (99 Navaho Ave. Ste. 102 Mankato MN 56001), Local delivery of chemotherapeutic agents for the treatment of periodontal disease.
  41. Cummins Joseph M., Low-dose oral administration of interferons.
  42. Takagishi Yasushi (Nishinomiya JPX) Doi Yoshio (Ibaraki JPX) Aita Kanji (Minoo JPX) Hoshi Noboru (Higashi-Kurume JPX), Medicament capsules for rectal application.
  43. Bomberger David C. ; Catz Paul G. ; Smedley Mark I. ; Stearns Paul C., Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced.
  44. Barr Arthur (2942 Shore Dr. Merrick NY 11566), Method for the oral treatment of dogs and other animals.
  45. Lin Matthew M. ; Lin Audrey H., Method of treating allergic rhinitis by delivering medication via the nasal vestibules.
  46. Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX) Yamashita Gentaro (Tachikawa JPX) Nagai Tsuneji (Taito JPX), Method of treating an injured part on the oral mucosa and the covering material for use thereof.
  47. Kovarik, Joseph E., Method of treating snoring and obstructive sleep apnea.
  48. Sackler, Richard S.; Goldenheim, Paul D.; Chasin, Mark; Burch, Ronald M.; Reder, Robert F.; Tigner, Joseph, Methods for providing safe local anesthesia.
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  50. Masters, David B.; Berg, Eric P., Mucoadhesive drug delivery devices and methods of making and using thereof.
  51. Moro, Daniel G.; Callahan, Howard; Nowotnik, David, Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds.
  52. Hussain Anwar A. (Lexington KY) Hirai Shinichiro (Lexington KY) Bawarshi Rima (Lexington KY), Nasal dosage forms of propranol.
  53. Kovarik, Joseph E., Non-surgical method and system for reducing snoring.
  54. Hussain Anwar A. (Lexington KY), Novel method of administering b
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  57. Tonetti Maurizio, Pharmaceutical composition to enhance tissue healing and regeneration and application kit comprising it.
  58. Cho Young W. (Chester NJ), Pharmaceutical compositions.
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  61. Tapolsky Gilles H. ; Osborne David W., Pharmaceutical preparation applicable to mucosal surfaces and body tissues.
  62. Tapolsky Gilles H. ; Osborne David W., Pharmaceutical preparation applicable to mucosal surfaces and body tissues.
  63. Uda Yoshiaki (Takarazuka JPX) Yashiki Takatsuka (Takarazuka JPX), Pharmaceutical preparations containing TRH or its analogue.
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  65. Dickerson, Jay; Mark, William; Trimmer, Annabelle; Jaeger, David; Alley, Amanda, Pharmaceutical suspension composition.
  66. Bremecker Klaus-Dieter (Marburg DEX) Hungerer Klaus-Dieter (Marburg DEX) Ronneberger Hansjrg (Marburg DEX), Pharmaceutical which can be administered nasally, a process for its preparation, and its use.
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  68. Goldenheim, Paul; Donigi-Gale, Donna; Sackler, Richard; Lacouture, Peter; Chasin, Mark, Prolonged anesthesia in joints and body spaces.
  69. Durrani Manzer J., Prolonged release bioadhesive vaginal gel dosage form.
  70. Masters, David B., Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof.
  71. Masters, David B.; Berg, Eric P., Protein biomaterials and biocoacervates and methods of making and using thereof.
  72. Masters, David B.; Berg, Eric P., Protein biomaterials and biocoacervates and methods of making and using thereof.
  73. Masters, David B., Protein matrix materials, devices and methods of making and using thereof.
  74. Masters, David B., Protein matrix materials, devices and methods of making and using thereof.
  75. Kawata Terushige (Tokushima JPX) Yamashita Shinsuke (Tokushima JPX), Sheet-shape adhesive preparation.
  76. Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX) Yamashita Gentaro (Koganei JPX), Slow-releasing medical preparation to be administered by adhering to a wet mucous surface.
  77. Kigasawa Kazuo (Tokyo JPX) Shimizu Hiroaki (Tokyo JPX) Hayashi Toshihiro (Chiba JPX) Watabe Kazuo (Kanagawa JPX) Tanizaki Akira (Tokyo JPX) Koyama Osamu (Tokyo JPX) Wakisaka Kikuo (Tokyo JPX) Ogawa Y, Soft buccal.
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  79. Deihl, Joseph A., Sprayable analgesic composition and method of use.
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  81. Gallopo Andrew R. (Garfield NJ) Dills Steven S. (Wharton NJ), Tablets having improved bioadhesion to mucous membranes.
  82. Randen Neil A. (Stillwater MN), Topical application of medicament in a binder.
  83. Song Suk-Zu (Flanders NJ) Mehta Surendra C. (Randolph NJ) Rashidbaigi Zahra A. (Nutley NJ) Nesbitt Russell U. (Somerville NJ) Fawzi Mahdi B. (Flanders NJ), Transdermal matrix system.
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  88. Cummins Joseph M., Treatment of viral disease with oral interferon-.alpha..
  89. Masters, David B.; Berg, Eric P., Wound treatments with crosslinked protein amorphous biomaterials.

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