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Fluorometric analyzer including shutter means for simultaneously shielding sample and photodetector during sample change 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-021/38
  • G01J-001/58
  • G01N-021/01
출원번호 US-0018152 (1979-03-07)
발명자 / 주소
  • Heiss Louis R. (Annapolis MD)
출원인 / 주소
  • Baxter Travenol Laboratories, Inc. (Deerfield IL 02)
인용정보 피인용 횟수 : 56  인용 특허 : 2

초록

A fluorometric analyzer includes a head assembly wherein the photomultiplier tube and excitation lamp of the analyzer are received in respective cavities and a transparent test cell is provided to receive a liquid sample. A first optical passage is provided between the lamp cavity and the test cell,

대표청구항

A head assembly for a fluorometric analyzer for measuring fluorescence in a liquid sample element contained within a test cell, wherein the analyzer includes, an excitation lamp element for applying radiation to the sample, and a photodetector element for detecting light produced as a result of fluo

이 특허에 인용된 특허 (2)

  1. Haunold Otto (Carlsbad CA) Greene Malbone W. (Vista CA), Photometer with stationary sample holder and rotatable shutter.
  2. Heiss ; Louis Robert, Temperature control and stirring apparatus for luminescence measuring photometer.

이 특허를 인용한 특허 (56)

  1. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated analyzer for performing a nucleic acid-based assay.
  2. Van Cleve, Mark David; Reid, Taylor Addison; Trondle, Linda Marie; Hung, Victoria; Luo, Yi; Rieger, Dennis Edwin; McMenamy, Evan Phillip; Raghavan, Nanditha; Reliford, Morkoah Blay; Canfield, Douglas John; Taine, Elaine Grace; Sinson, Edsel Lawrence Noche; Vande Wetering, Scott William; Taylor, Teri; Knox, Travis; Cuaresma Jacalne, Fran Zylo; Weston, James; Bao-Guey Chan, Jennifer; Ortega, Stephanie TuVi; Schell, Rachel Sarah; Diamond, Ronald Norman; Gann, Steve Michael; Hall, Eric Darnell; Hwang, Tae Ho; Morton, John Lewis; Moskalev, Anatoly; Stack, Marinela Gombosev; Sargeant, Bruce Alan; Forshager, Michelle Fredrika; Chua, Vanessa Camille; Wilson, Kylie, Automated immunoanalyzer system for performing diagnostic assays for allergies and autoimmune diseases.
  3. Van Cleve, Mark David; Taine, Elaine Grace; Canfield, Douglas John; Ortega, Stephanie TuVi; Reid, Taylor Addison, Automated immunoanalyzer system for performing diagnostic assays for autoimmune and infectious diseases.
  4. Van Cleve, Mark David; Taine, Elaine Grace; Canfield, Douglas John; Ortega, Stephanie TuVi; Reid, Taylor Addison, Automated immunoanalyzer system for performing diagnostic assays for autoimmune and infectious diseases.
  5. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  6. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  7. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  8. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  9. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated process for preparing and amplifying a target nucleic acid sequence.
  10. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated system for isolating and amplifying a target nucleic acid sequence.
  11. Ferber Alan C. (Hillside IL) Chamran ; deceased Morteza M. (late of Elmhurst IL by Delories M. Chamran ; legal representative), Automatic shutter system.
  12. Cohen, Beri, Clam-shell luminometer.
  13. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., Continuous process for performing multiple nucleic acid amplification assays.
  14. Vehra, Imran Sharif, Dark current correction in scinitillator detectors for downhole nuclear applications.
  15. Smith Roger E. (Bountiful UT) Smith Randall W. (Sandy UT), Detector assembly for analyzer instrument.
  16. Diamond, Ronald Norman; Gann, Steve Michael; Hall, Eric Darnell; Hwang, Tae Ho; Morton, John Lewis; Moskalev, Anatoly; Sargeant, Bruce Alan; Rieger, Dennis Edwin; Gombosev, Marinela; Van Cleve, Mark David, Device and associated methods for performing luminescence and fluorescence measurements of a sample.
  17. Diamond, Ronald Norman; Gann, Steve Michael; Hall, Eric Darnell; Hwang, Tae Ho; Morton, John Lewis; Moskalev, Anatoly; Sargeant, Bruce Alan; Rieger, Dennis Edwin; Gombosev, Marinela; Van Cleve, Mark David, Device and associated methods for performing luminescence and fluorescence measurements of a sample.
  18. Ammann,Kelly G.; Hansberry,Ernest V., Device for agitating the fluid contents of a container.
  19. Nishino, Norikazu; Fukamachi, Mitsuhiro; Obayashi, Fumio, Fluorescence measurement method and fluorescence measurement device.
  20. Ammann,Kelly G.; Schneider,Robert E.; Smith,Robert J., Incubator for use in an automated diagnostic analyzer.
  21. Burns,Ralph E., Instrument for detecting light emitted by the contents of a reaction receptacle.
  22. Gielisse Peter J. (Brewster MN), Method and apparatus for analyzing gems.
  23. Kolehmainen Seppo (P.O. Box 2805 Titusville FL 32780) Tarkkanen Veikko (Krijgersberglaan 25 6371 CA Schaesberg NLX 4), Method and apparatus for measurement of samples by luminescence.
  24. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for agitating the contents of a reaction receptacle within a temperature-controlled environment.
  25. Ammann, Kelly G.; Hansberry, Ernest V., Method for agitating the fluid contents of a container.
  26. Ammann, Kelly G.; Hansberry, Ernest V., Method for agitating the fluid contents of a container.
  27. Macioszek, Jerzy A.; Davis, Christopher B.; Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Scalese, Robert F.; Heinz, Robert E., Method for continuous mode processing of the contents of multiple reaction receptacles in a real-time amplification assay.
  28. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  29. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  30. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  31. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  32. Light, II, James P.; Carrick, James M., Method for determining the amount of an analyte in a sample.
  33. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for incubating the contents of a receptacle.
  34. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for introducing a fluid into a reaction receptacle contained within a temperature-controlled environment.
  35. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for performing an assay with a nucleic acid present in a specimen.
  36. Macioszek, Jerzy A.; Davis, Christopher B.; Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Scalese, Robert F.; Heinz, Robert E., Method for performing multi-formatted assays.
  37. Light, II, James P., Method for reducing the presence of amplification inhibitors in a reaction receptacle.
  38. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for simultaneously performing multiple amplification reactions.
  39. Knight, Byron J.; Opalsky, David; Schroeter, Brian, Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure.
  40. Burns,Ralph E.; Hansberry,Ernest V., Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer.
  41. Popelka Susan R. (Gurnee IL), Optical apparatus for fluorescence polarization instrument.
  42. Priarone Paolo (Hyattsville MD) St. John Peter A. (Adelphi MD), Photomultiplier protector for a fluorometer.
  43. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., Signal measuring system having a movable signal measuring device.
  44. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., System and method for incubating the contents of a reaction receptacle.
  45. Ammann, Kelly G.; Hansberry, Ernest V., System for agitating the fluid contents of a container.
  46. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., System for incubating the contents of a reaction receptacle.
  47. Knight, Byron J.; Li, Haitao, System for performing multi-formatted assays.
  48. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., System for performing multi-formatted assays.
  49. Knight, Byron J., System for processing contents of a receptacle to detect an optical signal emitted by the contents.
  50. Hayes, Matthew J.; Knight, Byron J.; Li, Haitao; Scalese, Robert F., Systems and methods for detecting multiple optical signals.
  51. Hayes, Matthew J.; Knight, Byron J.; Li, Haitao; Scalese, Robert F., Systems and methods for detecting multiple optical signals.
  52. Heinz, Robert E.; Newell, Dennis; Opalsky, David; Rhubottom, Jason, Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector.
  53. Heinz, Robert E.; Newell, Dennis; Opalsky, David; Rhubottom, Jason, Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector.
  54. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having a receptacle mixing mechanism.
  55. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having an arcuate closure panel.
  56. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having rotatable door.
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