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Immobilization of Streptokinase 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61L-015/03
  • A61F-013/00
  • A61K-009/70
출원번호 US-0074983 (1979-09-13)
발명자 / 주소
  • Everse Johannes (2613 Newcomb St. Lubbock TX 79430) Everse Kathleen E. (2613 Newcomb St. Lubbock TX 79430) Mercer Leo C. (4800 Alberta El Paso TX 79912)
인용정보 피인용 횟수 : 38  인용 특허 : 8

초록 ▼

The invention comprises the construction of an implantable device consisting of a clot lysing inhibitor immobilized onto a biocompatible polymer, and the method of regulation of blood clotting time, the prevention of blood clot formation, and the hydrolysis of existing blood clots with the use of sa

대표청구항

The process of control of blood clotting in a living mammal comprising: providing a clot-lysing initiator immobilized on a solid water insoluble non-colloidal substrate; and implanting said initiator supporting substrate in the body of said living mammal in contact with its body fluid.

이 특허에 인용된 특허 (8)

  1. Hyden Viktor Holger (Prastgardsgaten 2 Goteborg SW) Hasselblad Fritz Victor (St. Eriks Torg 3 Goteborg SW), Apparatus and method for selectively separating amino acids and defined proteins in blood.
    상세보기
  2. Emery Alden H. (West Lafayette WV) Lim Henry C. (West Lafayette WV) Kolarik Michael J. (South Charleston WV), Enzyme entrappment with cellulose acetate formulations.
    상세보기
  3. Weaver Mary Ollidene (Peoria IL) Bagley Edward B. (Morton IL) Fanta George F. (Peoria IL) Doane William M. (Morton IL), Immobilization of enzymes with a starch-graft copolymer.
    상세보기
  4. Heimburger Norbert (Frankfurt am Main DEX) Ronneberger Hansjorg (Frankfurt am Main DEX) Schick Manfred (Frankfurt am Main DEX), Method for the treatment of thromboembolism.
    상세보기
  5. Goldberg Bruce S. (Clifton NJ), Method of immobilizing proteinaceous substances.
    상세보기
  6. Ginger Leonard George (Glenview IL) Mather Adaline Nicoles (Evanston IL), Methods of dissolving blood clots and the like with streptokinase chemically bonded to a carbohydrate matrix.
    상세보기
  7. Vairel Edmond G. (Paris FR) Goulay Jean (Oissel FR) Choay Jean (Paris FR), Pharmaceutical compositions of stable urokinase-heparin complexes and methods for use thereof.
    상세보기
  8. Avrameas Stratis (La Celle Saint Cloud FR) Broun Georges (Rouen FR) Selegny Eric (Rouen FR) Thomas Daniel (Rouen FR), Preparation of active proteins cross-linked to inactive proteins.
    상세보기

이 특허를 인용한 특허 (38)

  1. Jarrett Robert D. (Painesville OH) McCain G. Howard (Painesville OH), Activation of biocompatible polymers with biologicals whose binding complements are pathological effectors.
    상세보기
  2. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  3. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  4. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  5. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  6. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  7. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  8. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  9. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D.; Osborne, Thomas A., Coated implantable medical device.
    상세보기
  10. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Voorhees, III, William D.; Kozma, Thomas G., Coated implantable medical device.
    상세보기
  11. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Voorhees, III, William D.; Kozma, Thomas G., Coated implantable medical device.
    상세보기
  12. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Voorhees, III, William D.; Kozma, Thomas G., Coated implantable medical device.
    상세보기
  13. Ragheb, Anthony O.; Bates, Brian L.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Coated implantable medical device.
    상세보기
  14. Ragheb,Anthony O.; Bates,Brian L.; Fearnot,Neal E.; Kozma,Thomas G.; Voorhees, III,William D.; Gershlick,Anthony H., Coated implantable medical device.
    상세보기
  15. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Voorhees, III, William D.; Kozma, Thomas G., Coated implantable medical device method.
    상세보기
  16. Bates, Brian L.; Boatman, Scott E.; Burton, David G.; Hoffa, Michael C.; Schaeffer, Darin G.; Sturgeon, Jason S.; Ragheb, Anthony O., Coated medical device.
    상세보기
  17. Bates, Brian L.; Ragheb, Anthony O.; Bourdeau, William J.; Fearnot, Neal E., Coated medical device.
    상세보기
  18. Bates, Brian L.; Ragheb, Anthony O.; Stewart, IV, Joseph M.; Bourdeau, William J.; Choules, Brian D.; Purdy, James D.; Fearnot, Neal E., Coated medical device.
    상세보기
  19. Bates, Brian L.; Ragheb, Anthony O.; Stewart, IV, Joseph M.; Bourdeau, William J.; Choules, Brian D.; Purdy, James D.; Fearnot, Neal E., Coated medical device.
    상세보기
  20. Bates, Brian L.; Ragheb, Anthony O.; Stewart, IV, Joseph M.; Bourdeau, William J.; Choules, Brian D.; Purdy, James D.; Fearnot, Neal E., Coated medical device.
    상세보기
  21. Bates, Brian L.; Ragheb, Anthony O.; Stewart, IV, Joseph M.; Bourdeau, William J.; Choules, Brian D.; Purdy, James D.; Fearnot, Neal E., Coated medical device.
    상세보기
  22. Ragheb, Anthony O.; Bates, Brian L.; Boatman, Scott E.; Burton, David G.; Hoffa, Michael C.; Schaeffer, Darin G.; Sturgeon, Jason S., Coated medical device.
    상세보기
  23. Koepf, Edward; Zimmerman, Thomas, Composition, method, and kit for preparing plasmin.
    상세보기
  24. Koepf, Edward; Lindsay, Myles; Silverstein, Rebecca; Hunt, Jennifer; Rebbeor, James; Zimmerman, Thomas; Miller, Charles; Caronna, Anthony; Stokes, Kenya, Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom.
    상세보기
  25. Van Antwerp William P., Indwelling catheter with stable enzyme coating.
    상세보기
  26. Speck, Ulrich; Scheller, Bruno, Medical device for dispensing medicaments.
    상세보기
  27. Speck, Ulrich; Scheller, Bruno, Medical device for dispersing medicaments.
    상세보기
  28. Speck, Ulrich; Scheller, Bruno, Medical device for dispersing medicaments.
    상세보기
  29. Ragheb,Anthony O.; Fearnot,Neal E.; Voorhees, III,William D.; Kozma,Thomas G.; Bates,Brian L.; Osborne,Thomas A., Method of treating a patient with a coated implantable medical device.
    상세보기
  30. Bates, Brian L.; Ragheb, Anthony O.; Fearnot, Neal E.; Kozma, Thomas G.; Voorhees, III, William D., Methods for making implantable medical devices.
    상세보기
  31. Smith Richard A. G. (Reigate Surrey GB2), Novel enzyme derivatives.
    상세보기
  32. Ferres Harry (Epsom GB2) Smith Richard A. G. (Reigate GB2) Garman Andrew J. (Betchworth GB2), Novel fibrinolytic enzyme compounds.
    상세보기
  33. Speck, Ulrich; Scheller, Bruno, Preparation for restenosis prevention.
    상세보기
  34. Speck, Ulrich; Scheller, Bruno, Preparation for restenosis prevention.
    상세보기
  35. Speck, Ulrich; Scheller, Brunn, Preparation for the prophylaxis of restenosis.
    상세보기
  36. Gupta, Nisha, Stabilized enzyme compositions.
    상세보기
  37. Gupta, Nisha; Rosenblatt, Joel, Stabilized enzyme compositions.
    상세보기
  38. Dean ; Jr. Robert C. (Norwich VT) Silver Frederick H. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Phillips Philip G. (Norwich VT) Runstadler ; Jr. Peter W. (Hanover NH), Weighted collagen microsponge for immobilizing bioactive material.
    상세보기

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