초록 ▼

Divisible tablet having controlled and delayed release of the active substance and consisting of a compact that is optionally provided with a coating and is formed by at least one active substance in an adjunct composition that effects a delayed and controlled release of the active substance and opt

Divisible tablet having controlled and delayed release of the active substance and consisting of a compact that is optionally provided with a coating and is formed by at least one active substance in an adjunct composition that effects a delayed and controlled release of the active substance and optionally one or more additional adjunct compositions that optionally contain active substances and are arranged in longitudinal layers, the compact being of an oblong shape in which the ratio of length to width to depth is approximately 2.5 to 5: approximately 0.9 to 2:1 and the width constitutes at most ⅔of the length, and in which one or more relatively deep dividing grooves are present which run perpendicularly to the length and the depth and have a total depth constituting from approximately ⅓to approximately ½of the depth of the tablet, but are at least so deep that one fracture surface area multiplied by the number of possible fragments constitutes a maximum of 15% of the surface area of the undivided tablet, the base and top faces independently of one another are planar or are convexly curved about the longitudinal axis or about parallels to this axis, the side faces are planar, the end faces can be of any shape and edges are optionally bevelled or rounded.

대표청구항 ▼

A divisible tablet having controlled and delayed release of the active substance, characterised in that it consists of a compact, with or without a coating having no influence on the release of said active substance, said compact being formed by pressing a granulate of at least one active substance

A divisible tablet having controlled and delayed release of the active substance, characterised in that it consists of a compact, with or without a coating having no influence on the release of said active substance, said compact being formed by pressing a granulate of at least one active substance and an adjunct composition which effects the controlled and delayed release of the active substance to form a granulate-retard matrix, with or without one or more additional granulate adjunct compositions which contain an active substance or do not contain such active substance and are arranged in longitudinal layers, the compact being of an ablong shape in which the ratio of length to width to depth is approximately 2.5 to 5:approximately 0.9 to 2:1 and the width constitutes at most ⅔of the length, and in which one or more deep dividing groves are present which run perpendicularly to the length and depth and have a total depth of from approximately ⅓to approximately ½of the depth of the tablet, but are at least so deep that one fracture surface area multiplied by the number of possible fragments constitutes a maximum of 15% of the surface area of the undivided tablet, the base and top faces independently of one another are planar or are convexly curved about the longitudinal axis or about parallels to this axis, the side faces are planar, the end faces can be of any shape and with or without bevelled or rounded edges.