초록 ▼

A method and composition for a film forming antimicrobial material for animal skin wherein said film is resistant to body fluids and provides long term protection against microorganisms. The composition comprises an alcohol soluble carboxylated polycrylate wherein is added an antimicrobial agent, a

A method and composition for a film forming antimicrobial material for animal skin wherein said film is resistant to body fluids and provides long term protection against microorganisms. The composition comprises an alcohol soluble carboxylated polycrylate wherein is added an antimicrobial agent, a topical adhesion promoter, and a difunctional amide which crosslinks said polymer as said solvent evaporates. The topical film so formed does not interfere with respiratory processes and is inert to blood, urine, gastric acids, perspiration, saline solutions and the like. Once formed, said film will not resolubilize in alcohol or other common sterilants. Said topical film adheres to tissue and is resistant to physical removal and to abrasion. Film longevity is in excess of 2 days. Substantial protection is provided against pathogenic bacteria and fungi often implicated in hospital infections and thus can serve as a presurgical dressing, preparation agent, as well as in post-surgical prophylaxis.

대표청구항 ▼

An alcohol insoluble, antimicrobial topical coating composition comprising: A. from about 6% to about 13% by weight of said composition of a lower acrylate interpolymer which has the formula: [Figure] wherein R and R1 each represents hydrogen and methyl, R2 represents either methyl, ethyl, propyl or

An alcohol insoluble, antimicrobial topical coating composition comprising: A. from about 6% to about 13% by weight of said composition of a lower acrylate interpolymer which has the formula: [Figure] wherein R and R1 each represents hydrogen and methyl, R2 represents either methyl, ethyl, propyl or butyl; R3 represents methyl or ethyl; n represents from 3 to 12 weight percent based on combined weight of x, y and z; x represents from 8 to 25 weight percent based on the combined weight of n and z; y represents from 45 to 89 weight percent based on combined weight of n, x and z; z represents from 0 to 44 weight percent based on the combined weights of n, x and y, the sum of the numerical values of n+x+y+z s always 100 and the groups n, x, y and z are present in the polymer in a heterogeneous relative order; B. from about 1% to about 3% by weight of said composition of urea as a cross linking agent; and C. the remainder comprising an adhesion-promoting material selected from the group consisting of a secondary solvent, an emollient, and mixtures thereof, and at least one antimicrobial agent.