초록 ▼

A composite material of de-N-acetylated chitin and fibrous collagen, which may be prepared by bringing the de-N-acetylated chitin and the fibrous collagen into mutual contact in an aqueous acidic medium followed by deacidifying the obtained product, the fibrous collagen being able to be partially re

A composite material of de-N-acetylated chitin and fibrous collagen, which may be prepared by bringing the de-N-acetylated chitin and the fibrous collagen into mutual contact in an aqueous acidic medium followed by deacidifying the obtained product, the fibrous collagen being able to be partially replaced by gelatin and/or soluble collagen, and a shaped material derived from the composite material is excellent in mechanical strength, heat-resistance and biostability and advantageously employed in the field of medical materials, edibles such as edible casing and base materials for inmobilizing enzyme.

대표청구항 ▼

1. Composite thrombogenic, physiological saline solution-insoluble material of de-N-acetylated chitin and fibrous collagen. 2. Composite material of claim 1, wherein the fibrous collagen is partially replaced by gelatin and/or soluble collagen. 3. Composite material of claim 1 or 2, wherein the fibr

1. Composite thrombogenic, physiological saline solution-insoluble material of de-N-acetylated chitin and fibrous collagen. 2. Composite material of claim 1, wherein the fibrous collagen is partially replaced by gelatin and/or soluble collagen. 3. Composite material of claim 1 or 2, wherein the fibrous collagen is previously cross-linked or acylated. 4. Composite material of any one of claims 1 to 3, which is further cross-linked. 5. Edible material comprising the composite material of any one of claims 1 to 4. 6. Medical material comprising the composite material of any one of claims 1 to 4. 7. Base material for immobilizing enzyme, comprising the composite material of any one of claims 1 to 4. 8. A method for preparing a composite material of claim 1, comprising bringing de-N-acetylated chitin into contact with fibrous collagen in an acidic medium followed by deacidifying the obtained product. 9. A method of claim 8, wherein the contact of the de-N-acetylated chitin with the fibrous collagen is effected by mixing an aqueous acidic solution of the de-N-acetylated chitin and an aqueous dispersion of fibrous collagen. 10. A method of claim 8, wherein the contact of the de-N-acetylated chitin with the fibrous collagen is effected by immersing a previously shaped material of the fibrous collagen into an aqueous acidic solution of the de-N-acetylated chitin. 11. A method of any one of claims 8 to 10, wherein the fibrous collagen is partially replaced by gelatin and/or soluble collagen. 12. A method of claim 8, wherein the fibrous collagen is previously cross-linked or acylated before the contact with the de-N-acetylated chitin. 13. A method of claim 8, wherein the deacidifying is effected by the addition of an aqueous alkaline solution to said obtained product, by the removal of the acid in said acidic medium by evaporation, or by the electrodeposition of said obtained product wherein said acid is neutralized by OH - ions formed by said electrodeposition. 14. A method of claim 8, wherein the resultant composite material is further cross-linked.