초록 ▼

Pleasant-tasting, non-greasy, edible compositions, preferably in liquid form, comprising edible oil or oil-like materials, a high potency, lipid soluble sweetener, such as saccharin, and a lipid soluble flavorant, are disclosed. These compositions are particularly useful as an oral dosage form for v

Pleasant-tasting, non-greasy, edible compositions, preferably in liquid form, comprising edible oil or oil-like materials, a high potency, lipid soluble sweetener, such as saccharin, and a lipid soluble flavorant, are disclosed. These compositions are particularly useful as an oral dosage form for vitamins or pharmaceutical materials; in such embodiments the edible oil-like material may consist, in whole or in part, of an oily pharmaceutical agent, such as polyol fatty acid esters having at least four fatty acid ester groups, each fatty acid having from about 8 to about 22 carbon atoms.

대표청구항 ▼

1. A liquid pharmaceutical composition in oral dosage from comprising from about 25% to about 99.9% of an edible oil or oil-like pharmaceutical agent selected from polyol fatty acid esters having at least 4 fatty acid ester groups, such fatty acid having from about 8 to about 22 carbon atoms; made m

1. A liquid pharmaceutical composition in oral dosage from comprising from about 25% to about 99.9% of an edible oil or oil-like pharmaceutical agent selected from polyol fatty acid esters having at least 4 fatty acid ester groups, such fatty acid having from about 8 to about 22 carbon atoms; made more palatable by incorporating in said pharmaceutical composition from about 0.001% to about 5% of a highly potent, lipid soluble sweetener, and from about 0.1% to about 5% of a lipid soluble flavorant. 2. A composition according to claim 1 wherein the sweetener is selected from the group consisting of saccharin, alkoxy aromatics, oximes, sulfamic acids, dihydrochalcones, aspartyl malonates, succanilic acids, and mixtures thereof. 3. A composition according to claim 2 which comprises from about 0.01% to about 1% of said sweetener. 4. A composition according to claim 3 wherein the sweetener is saccharin. 5. A composition according to claim 3 which comprises from about 0.1% to about 1% of the flavorant. 6. A pharmaceutical composition according to claim 1 wherein the flavorant is a natural or artificial mint flavor. 7. A pharmaceutical composition according to claim 6 wherein said flavorant is a natural or artificial peppermint flavor. 8. A pharmaceutical composition according to claim 1 which comprises from about 0.25% to about 0.5% of the sweetener. 9. A pharmaceutical composition according to claim 8 which comprises from about 0.25% to about 0.75% of the flavorant. 10. A pharmaceutical composition according to claim 9 wherein the pharmaceutical agent is sucrose octaoleate. 11. A process for preparing an edible liquid composition according to claim 1 wherein the sweetener component is solubilized in the edible oil or oil-like material and the flavorant is subsequently added to this mixture in a manner so as not to lose the volatile components contained in said flavorant.