초록 ▼

A novel system and method for treating ischemic neurologic tissue is disclosed wherein an oxygenated nutrient emulsion is circulated through at least a portion of the cerebospinal pathway. The nutrient emulsion contains an oxygenatable non-aqueous component, an aqueous nutrient component, an emulsif

A novel system and method for treating ischemic neurologic tissue is disclosed wherein an oxygenated nutrient emulsion is circulated through at least a portion of the cerebospinal pathway. The nutrient emulsion contains an oxygenatable non-aqueous component, an aqueous nutrient component, an emulsification component, and other components which render physiologic acceptability of the nutrient emulsion. Methods for producing the nutrient emulsion and a system for delivering that emulsion to the cerebrospinal pathway are also disclosed. Additionally, novel diagnostic methods for diagnosing the physiologic state of hypoxic-ischemic and other diseased neurologic tissue during treatment are provided.

대표청구항 ▼

A method of treating hypoxic-ischemic neurologic tissue, in mammals, comprising: (a) providing a physiologically acceptable synthetic oxygenatable fluid; (b) oxygenating said oxygenatable fluid to produce an oxygenated fluid; (c) injecting a substantially continuous stream of said oxygenated fluid i

A method of treating hypoxic-ischemic neurologic tissue, in mammals, comprising: (a) providing a physiologically acceptable synthetic oxygenatable fluid; (b) oxygenating said oxygenatable fluid to produce an oxygenated fluid; (c) injecting a substantially continuous stream of said oxygenated fluid into the cerebrospinal fluid pathway, at a first injection point; (d) substantially continuously withdrawing fluid from said cerebrospinal fluid pathway at a second point which is selected to create a circulation of said oxygenated fluid in the vicinity of said ischemic tissue; whereby ischemic neurologic tissue will be oxygenated and otherwise nourished by said fluid.