초록 ▼

A closed system for separately storing and selectively mixing two components, such as a drug and a diluent, under sterile conditions. The closed system can incorporate a drug vial of standard construction. A unique junction of the closed system permits a drug vial with a drug therein to be connected

A closed system for separately storing and selectively mixing two components, such as a drug and a diluent, under sterile conditions. The closed system can incorporate a drug vial of standard construction. A unique junction of the closed system permits a drug vial with a drug therein to be connected in a sterile manner with a compressible chamber having a diluent therein, after the drug and diluent have been separately sterilized. The junction encloses the end portions of access means to each of the receptacles, maintaining the end portions in sterile, spaced relation and providing for the selective establishment of a sterile pathway between the drug and diluent for mixing in a closed environment. The compressible chamber is of a unique design including gas-trapping and reservoir compartments in open communication. The compressible chamber is utilized with the junction to provide an efficient, sterile storage and mixing system.

대표청구항 ▼

A closed system for selectively mixing two separately stored components under sterile conditions, comprising: (a) a compressible chamber including a selectively gas-trapping compartment and a reservoir compartment in open communication with said gas-trapping compartment, said compressible chamber co

A closed system for selectively mixing two separately stored components under sterile conditions, comprising: (a) a compressible chamber including a selectively gas-trapping compartment and a reservoir compartment in open communication with said gas-trapping compartment, said compressible chamber containing the first component, which is a sterile liquid; (b) a container containing the second component, which is sterile, at least one of said container and said chamber also containing a sterile gas; (c) first means to access said chamber, adjacent said gas-trapping compartment; (d) second means to access said container; (e) junction means permanently affixed about at least the end portions of each of said access means, said junction means selectively maintaining said end portions in sterile relation; (f) at least one of said access means including an element capable of selectively piercing said junction means so as to connect said first and second access means and establish a sterile pathway between said container and said chamber, through said first and second access means; (g) whereupon after said sterile pathway is established, said gas-trapping and reservoir compartments may be selectively positioned to facilitate the proper mixing of the first and second components.