초록 ▼

A method for preparing a 195mAu-containing liquid is provided. In the method, 195mHg is adsorbed on an adsorption agent and then the daughter radioisotope 195mAu is eluted from the adsorption agent with an eluant containing a gold-complexing agent. The adsorption agent comprises a mercury ion-bindin

A method for preparing a 195mAu-containing liquid is provided. In the method, 195mHg is adsorbed on an adsorption agent and then the daughter radioisotope 195mAu is eluted from the adsorption agent with an eluant containing a gold-complexing agent. The adsorption agent comprises a mercury ion-binding material having a substantially stronger adsorption affinity for mercury ions than for gold ions. Also disclosed are a radioisotope generator capable of producing a 195mAu-containing liquid and a process for conducting a radiodiagnostic examination on a warm-blooded animal using a 195mAu-containing liquid.

대표청구항 ▼

A method of preparing a non-toxic, pharmaceutically acceptable, 195mAu-containing liquid capable of direct administration in a living being and substantially devoid of 195mHg ions, wherein the 195mAu is a daughter radioisotope of the 195mHg ion, comprising: (a) adsorbing 195mHg on a chemically and r

A method of preparing a non-toxic, pharmaceutically acceptable, 195mAu-containing liquid capable of direct administration in a living being and substantially devoid of 195mHg ions, wherein the 195mAu is a daughter radioisotope of the 195mHg ion, comprising: (a) adsorbing 195mHg on a chemically and radiolytically stable adsorption agent comprising a mercury ion-binding material having a significantly higher affinity for mercury ions than for gold ions, and (b) eluting the daughter 195mAu radioisotope with an eluant which selectively converts 195mAu ions to an elutable form in the presence of the adsorbed parent 195mHg radioisotope, and which is non-toxic and pharmaceutically acceptable.