초록 ▼

An apparatus for the continuous flow fractionation of whole blood incorporates motor driven whole blood, anticoagulant and replacement pumps, negative and positive pressure monitors, and a dual bubble detector which function in conjunction with a disposable single-use flow system and a hollow fiber

An apparatus for the continuous flow fractionation of whole blood incorporates motor driven whole blood, anticoagulant and replacement pumps, negative and positive pressure monitors, and a dual bubble detector which function in conjunction with a disposable single-use flow system and a hollow fiber filter to separate and collect plasma from whole blood. Operation of the pump motors, pressure monitors and bubble detector is controlled by a control circuit within the apparatus to provide one of several operator-selected operating modes, including run, prime and reinfuse modes. The control circuit provides an alarm which can be cancelled by the operator when certain system parameters fall outside of normal operating limits, and interrupts operation of the pumps when the parameters exceed maximum limits. A failsafe circuit independent of the control circuits interrupts power to the pump motors in the event the motors do not stop upon detection of a bubble or fluid absence in the flow system.

대표청구항 ▼

In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a moni

In a blood fractionation apparatus operable in conjunction with a disposable fluid flow system for separating and collecting a blood fraction from whole blood, and including at least one motor-driven pump for conveying blood through the flow system, a tachometer associated with the motor, and a monitoring device providing an alarm signal in the presence of a fluid absence in the system, a failsafe control circuit comprising, in combination: a flip-flop responsive to applied tachometer pulses from the pump motor for producing an alarm control signal; a series-parallel counter having a reset input, a clock input and a series/parallel enable input, said counter requiring a predetermined number of applied clock pulses following application of a serial enabling signal for producing an output; means for applying said flip-flop output signal to said parallel-serial enable input to enable said counter to a serial mode upon occurrence of said tach pulses; means for applying said fluid absence alarm signal to said reset input to enable operation of said counter upon the occurrence of a fluid absence in the system; means for applying clock pulses to said counter whereby said counter counts to zero over a predetermined time interval upon being conditioned to a serial mode at said serial-enable input and upon being enabled at said reset input; and means responsive to the output of said counter for terminating operation of the pump.