초록 ▼

Pressure sensitive adhesive having favorable adhesive, shear, liquid permeability, and release characteristics. The adhesive is a crosslinked polymerization product of a methyl/phenyl siloxane gum, dimethyl siloxane gum and a polysiloxane resin. The resulting product provides suitable adhesion to a

Pressure sensitive adhesive having favorable adhesive, shear, liquid permeability, and release characteristics. The adhesive is a crosslinked polymerization product of a methyl/phenyl siloxane gum, dimethyl siloxane gum and a polysiloxane resin. The resulting product provides suitable adhesion to a large number of surfaces and has particular utility as an adhesive between plastic film and human skin, especially for use with transdermal therapeutic devices. The adhesive characteristic mitigates damage to underlying surfaces such as human skin tissue during adhesive removal.

대표청구항 ▼

A combination of a medical device to be placed in adhesive contact with the skin and a pressure sensitive adhesive at least partially coated on said device, the adhesive permitting passage of medicinal liquids therethrough, said adhesive comprising: the polymerization product of a mixture of reactan

A combination of a medical device to be placed in adhesive contact with the skin and a pressure sensitive adhesive at least partially coated on said device, the adhesive permitting passage of medicinal liquids therethrough, said adhesive comprising: the polymerization product of a mixture of reactants comprised of a linear methyl/phenyl polysiloxane gum, comprising dimethyl diphenyl polysiloxane, a linear dimethyl polysiloxane gum, and an MQ organopolysiloxane comprising monofunctional and quadrifunctional siloxane units, the adhesive permitting passage of nitroglycerine therethrough at a substantially constant rate of at least 30 mg/hr./cm2 as measured over a 27-hour period with the adhesive having a thickness of about 1.0-3.5 mil and permitting at least 90 percent of the adhesive surface of the transdermal device in contact with the skin to remain adhesive after 24 hours.