초록

Present invention provides a unique drug delivery device for delivering drug by injection into a body. The drug delivery system comprises the drug and polymer which is a liquid at room temperature and a semi-solid or gel at the body temperature.

대표청구항 ▼

An aqueous pharmaceutical composition for injection into a body to treat a condition requiring pharmacological treatment comprising a. 10% to 50% by weight of a polymer of the formula [Figure] wherein w is an integer of from 2 to 6 containing approximately 40% to 80% poly(oxyethylene) and approximat

An aqueous pharmaceutical composition for injection into a body to treat a condition requiring pharmacological treatment comprising a. 10% to 50% by weight of a polymer of the formula [Figure] wherein w is an integer of from 2 to 6 containing approximately 40% to 80% poly(oxyethylene) and approximately 20 to 60% poly(oxypropylene) and having a molecular weight of 7,000 to 50,000; and x and y are any integer within the above constraints; and b. a pharmacologically effective amount of drug selected from the group consisting of antibacterial substances, antihistamines and decongestants, anti-inflammatories, antiparasitics, antiviral, local anesthetics, antifungal, amebecidal, or trichomonocidal agents, analgesics, antiarthritics, antiasthmatics, anticoagulants, anticonvulsants, antidepressants, antidiabetics, antineoplastics, antipsychotics, antihypertensives and muscle relaxants; and c. a pharmaceutically acceptable acid or base being in sufficient quantity to adjust the pH of the composition to range from 2 to 9 and wherein the composition is liquid at about room temperature or below.