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Collagen-thrombin compositions 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C08L-089/06
  • A61K-035/14
  • C08H-001/06
출원번호 US-0552110 (1983-11-16)
발명자 / 주소
  • Cioca Gheorghe (Coatesville PA)
출원인 / 주소
  • Seton Company (Newark NJ 02)
인용정보 피인용 횟수 : 121  인용 특허 : 4

초록 ▼

A method of forming a collagen-thrombin hemostatic composition is comprised of forming a homogeneous aqueous admixture of collagen and thrombin at a basic pH and lyophilizing the collagen-thrombin admixture to form a stable collagen sponge having thrombin therein. The collagen utilized in the proces

대표청구항 ▼

A method of forming a collagen-thrombin hemostatic composition consisting essentially of: forming a homogeneous aqueous admixture of collagen and thrombin at a basic pH, wherein the ratio of collagen to thrombin is about 0.1 gram of collagen to about 300 units or greater of thrombin; and lyophilizin

이 특허에 인용된 특허 (4)

  1. Miyata Teruo (Tokyo NJ JPX) Rubin Albert L. (Englewood NJ) Stenzel Kurt H. (Englewood NJ), Chemically-modified fiber collagen hemostatic agents.
    상세보기
  2. Cioca Gheorghe (Coatesville PA), Collagen sponge.
    상세보기
  3. Stroetmann Michael (Mnster DEX), Fibrinogen-containing dry preparation, manufacture and use thereof.
    상세보기
  4. Schwarz Otto (Vienna ATX) Linnau Yendra (Vienna ATX) Lblich Franz (Vienna ATX) Seelich Thomas (Vienna ATX), Tissue adhesive.
    상세보기

이 특허를 인용한 특허 (121)

  1. Chi Sing, Eduardo; Ashby, Mark, Absorbable sponge with contrasting agent.
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  2. Sing Eduardo Chi ; Ashby Mark, Absorbable sponge with contrasting agent.
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  3. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Adhesive tissue repair patch.
    상세보기
  4. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Adhesive tissue repair patch and collagen sheets.
    상세보기
  5. Brenneman,Rodney; Cragg,Andrew H., Apparatus and method for percutaneous sealing of blood vessel punctures.
    상세보기
  6. Rhee,Woonza M.; DeLustro,Frank A.; Berg,Richard A., Biocompatible crosslinked composition.
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  7. Ashby, Mark; Bertolet, Roy D.; Tran, Tin T.; Cragg, Andrew H., Cinching loop.
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  11. Chu George H. (Sunnyvale CA) Ogawa Yasushi (Pacifica CA) McPherson John M. (Hopkinton MA) Ksander George (Redwood City CA) Pratt Bruce (Union City CA) Hendricks Diana (Brea CA) McMullin Hugh (San Bru, Collagen wound healing matrices and process for their production.
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  12. Ksander George (Redwood City CA) Ogawa Yasushi (Pacifica CA), Collagen wound healing matrices and process for their production.
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  19. Prior Jeffrey J. ; Wallace Donald G. ; Sierra David H. ; DeLustro Frank A., Compositions containing thrombin and microfibrillar collagen and methods for preparation and use thereof.
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  54. Møller, Lene; Devantier, Kristina; Wulff, Trine; Sabra, Mads Christian, Haemostatic composition comprising hyaluronic acid.
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  58. Pendharkar, Sanyog M.; Gorman, Anne J., Hemostatic compositions containing sterile thrombin.
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